Sheila Laverty
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View article: Ultrasonographic assessment of equine metacarpal cartilage thickness is more accurate than computed tomographic arthrography
Ultrasonographic assessment of equine metacarpal cartilage thickness is more accurate than computed tomographic arthrography Open
Articular cartilage can be directly imaged using ultrasonography. The fetlock is a common site of osteochondrosis, with the sagittal ridge of the third metacarpal bone most commonly affected. In osteochondrosis, cartilage thickening may be…
View article: Degradation of Proteoglycans and Collagen in Equine Meniscal Tissues
Degradation of Proteoglycans and Collagen in Equine Meniscal Tissues Open
Investigate meniscal extracellular matrix degradation. Equine menisci (n = 34 from 17 horses) were studied. Site-matched sections were cut and scored from three regions (ROIs; n = 102) and stained for histology, proteoglycan (safranin O an…
View article: Screening ultrasonographic findings of Thoroughbred weanling horses show agreement with concurrent radiographic examination and with subsequent yearling sales radiographs
Screening ultrasonographic findings of Thoroughbred weanling horses show agreement with concurrent radiographic examination and with subsequent yearling sales radiographs Open
Summary Background A screening ultrasonographic examination of yearling Thoroughbred horses has been described which can be performed on farm, as an adjunct to pre‐sale yearling radiography. Objectives To compare ultrasonographic and radio…
View article: Vascularity evaluation of the equine tarsocrural and proximal intertarsal joint septum, and comparative analysis of two arthroscopic transection techniques
Vascularity evaluation of the equine tarsocrural and proximal intertarsal joint septum, and comparative analysis of two arthroscopic transection techniques Open
Objective To evaluate vascularity of the synovial membrane covered septum (SMS) separating the tarsocrural (TC) and proximal intertarsal (PIT) joints (Part 1) and compare two methods of transection, electrosurgical or Ferris Smith rongeur …
View article: Radiographic analysis in Thoroughbreds reveals morphological changes in healthy maturing stifle joints and possible association between subchondral lesions and femoral condyle width
Radiographic analysis in Thoroughbreds reveals morphological changes in healthy maturing stifle joints and possible association between subchondral lesions and femoral condyle width Open
OBJECTIVE Assess femorotibial features in foals with and without medial femoral condyle (MFC) subchondral radiolucencies (SR+ and SR–). METHODS 3 independent, sequential radiographic studies were performed. Study 1 retrospectively measured…
View article: <scp>Micro‐computed tomography</scp> reveals high‐density mineralised protrusions and microstructural lesions in equine stifle joint articular cartilage
<span>Micro‐computed tomography</span> reveals high‐density mineralised protrusions and microstructural lesions in equine stifle joint articular cartilage Open
Background Stifle osteoarthritis (OA) lesions are most common in the medial femorotibial (MFT) compartment. Their characterisation and mapping will inform equine veterinarians towards an accurate diagnosis of OA. Objectives Investigate and…
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View article: Author response for "Osteoclast density is not increased in bone adjacent to radiolucencies (cysts) in juvenile equine medial femoral condyles"
Author response for "Osteoclast density is not increased in bone adjacent to radiolucencies (cysts) in juvenile equine medial femoral condyles" Open
View article: Microstructural changes at the osteochondral junction in naturally occurring osteoarthritis of the equine medial femorotibial joint
Microstructural changes at the osteochondral junction in naturally occurring osteoarthritis of the equine medial femorotibial joint Open
View article: Development of a computer-based quantification method for immunohistochemically-stained tissues and its application to study mast cells in equine wound healing (proof of concept)
Development of a computer-based quantification method for immunohistochemically-stained tissues and its application to study mast cells in equine wound healing (proof of concept) Open
View article: Development of a computer-based quantification method for immunohistochemically-stained tissues and its application to study mast cells in equine wound healing (proof of concept)
Development of a computer-based quantification method for immunohistochemically-stained tissues and its application to study mast cells in equine wound healing (proof of concept) Open
Background : There is a growing interest in the scientific community to use computer-based software programs for the quantification of cells during physiological and pathophysiological processes. Drawbacks of computer-based methods current…
View article: Maturation of the equine medial femoral condyle osteochondral unit
Maturation of the equine medial femoral condyle osteochondral unit Open
View article: Maturation of the Meniscal Collagen Structure Revealed by Polarization-Resolved and Directional Second Harmonic Generation Microscopy
Maturation of the Meniscal Collagen Structure Revealed by Polarization-Resolved and Directional Second Harmonic Generation Microscopy Open
View article: Development of a computer-based quantification method for immunohistochemically-stained tissues and its application to study mast cells in equine wound healing (proof of concept)
Development of a computer-based quantification method for immunohistochemically-stained tissues and its application to study mast cells in equine wound healing (proof of concept) Open
Background: There is a growing interest in the scientific community to use computer-based software programs for the quantification of cells during physiological and pathophysiological processes. Drawbacks of current computer-based methods …
View article: Development of a computer-based quantification method for immunohistochemically-stained tissues and its application to study mast cells in equine wound healing (proof of concept)
Development of a computer-based quantification method for immunohistochemically-stained tissues and its application to study mast cells in equine wound healing (proof of concept) Open
Background There is a growing interest in the scientific community to use computer-based software programs for the quantification of cells during physiological and pathophysiological processes. Drawbacks of current computer-based methods u…
View article: Short link N acts as a disease modifying osteoarthritis drug
Short link N acts as a disease modifying osteoarthritis drug Open
Osteoarthritis (OA) is a degenerative joint disease characterised by a progressive degradation of articular cartilage and underlaying bone and is associated with pain and disability. Currently, there is no medical treatment to reverse or e…
View article: BSE-SEM studies of articular cartilage and subchondral bone in naturally occurring post-traumatic equine carpal osteoarthritis
BSE-SEM studies of articular cartilage and subchondral bone in naturally occurring post-traumatic equine carpal osteoarthritis Open
View article: Medial femoral condyle cystic lesions in juvenile horses arise from focal trauma to the osteochondral junction in first 2 months of life
Medial femoral condyle cystic lesions in juvenile horses arise from focal trauma to the osteochondral junction in first 2 months of life Open
View article: Maturation of the medial femoral condyle epiphyseal growth plate and osteochondral junction
Maturation of the medial femoral condyle epiphyseal growth plate and osteochondral junction Open
View article: Synovial nerve fiber density decreases with naturally-occurring osteoarthritis in horses
Synovial nerve fiber density decreases with naturally-occurring osteoarthritis in horses Open
View article: Biomarkers for equine joint injury and osteoarthritis
Biomarkers for equine joint injury and osteoarthritis Open
We report the results of a symposium aimed at identifying validated biomarkers that can be used to complement clinical observations for diagnosis and prognosis of joint injury leading to equine osteoarthritis (OA). Biomarkers might also pr…
View article: Equine meniscal degeneration is associated with medial femorotibial osteoarthritis
Equine meniscal degeneration is associated with medial femorotibial osteoarthritis Open
Summary Background There is limited information available concerning normal equine meniscal morphology, its degeneration and role in osteoarthritis ( OA ). Objectives To characterise normal equine meniscal morphology and lesions and to exp…
View article: Clinical indications, complications, and long-term outcome of esophageal surgeries in 27 horses.
Clinical indications, complications, and long-term outcome of esophageal surgeries in 27 horses. Open
The main objective of this retrospective study was to describe clinical findings, management, and short- and long-term outcome in 27 horses that underwent various surgical techniques for esophageal disease. Surgical techniques (sometimes c…
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From Le Roux AB, et al.Transverse ultrasonographic (A) and histopathologic (B, C) images of the jejunum from a
View article: Comparison of an alcohol-based hand rub and water-based chlorhexidine gluconate scrub technique for hand antisepsis prior to elective surgery in horses.
Comparison of an alcohol-based hand rub and water-based chlorhexidine gluconate scrub technique for hand antisepsis prior to elective surgery in horses. Open
This prospective clinical study evaluates the effectiveness of an alcohol-based hand rub (Avagard™) for pre-surgical hand antisepsis in an equine hospital and compares it with traditional scrubbing technique using 4% chlorhexidine gluconat…
View article: Femoral epiphyseal cartilage matrix changes at predilection sites of equine osteochondrosis: Quantitative MRI, second‐harmonic microscopy, and histological findings
Femoral epiphyseal cartilage matrix changes at predilection sites of equine osteochondrosis: Quantitative MRI, second‐harmonic microscopy, and histological findings Open
Osteochondrosis is an ischemic chondronecrosis of epiphyseal growth cartilage that results in focal failure of endochondral ossification and osteochondritis dissecans at specific sites in the epiphyses of humans and animals, including hors…
View article: Differences in the vascular tree of the femoral trochlear growth cartilage at osteochondrosis‐susceptible sites in foals revealed by SWI 3T MRI
Differences in the vascular tree of the femoral trochlear growth cartilage at osteochondrosis‐susceptible sites in foals revealed by SWI 3T MRI Open
Focal ischemic chondronecrosis of epiphyseal growth cartilage (EGC) during endochondral ossification is believed to be a key early event on the pathway to osteochondrosis (OC) in both animals and humans. The lateral ridge of the equine tro…
View article: The Impact of Collagen Fibril Polarity on Second Harmonic Generation Microscopy
The Impact of Collagen Fibril Polarity on Second Harmonic Generation Microscopy Open
View article: Osteoclasts are recruited to the subchondral bone in naturally occurring post-traumatic equine carpal osteoarthritis and may contribute to cartilage degradation
Osteoclasts are recruited to the subchondral bone in naturally occurring post-traumatic equine carpal osteoarthritis and may contribute to cartilage degradation Open