Sheila Nevermann
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View article: The multiple functions of miR-574-5p in the neuroblastoma tumor microenvironment
The multiple functions of miR-574-5p in the neuroblastoma tumor microenvironment Open
Neuroblastoma is the most common extracranial solid tumor in childhood and arises from neural crest cells of the developing sympathetic nervous system. Prostaglandin E 2 (PGE 2 ) has been identified as a key pro-inflammatory mediator of th…
View article: Small extracellular vesicle‐derived miR‐574‐5p regulates PGE2‐biosynthesis via TLR7/8 in lung cancer
Small extracellular vesicle‐derived miR‐574‐5p regulates PGE2‐biosynthesis via TLR7/8 in lung cancer Open
Intercellular communication plays an essential role in lung cancer (LC). One of the major players in cell‐cell‐communication is small extracellular vesicles (sEV). SEV trigger various biological responses by transporting cellular cargo to …
View article: Extracellular Vesicle-Based Detection of Pancreatic Cancer
Extracellular Vesicle-Based Detection of Pancreatic Cancer Open
Due to a grim prognosis, there is an urgent need to detect pancreatic ductal adenocarcinoma (PDAC) prior to metastasis. However, reliable diagnostic imaging methods or biomarkers for PDAC or its precursor lesions are still scarce. ADAM8, a…