Sheila Patrick
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View article: List of Recommended Names for bacteria of medical importance: report of the Ad Hoc Committee on Mitigating Changes in Prokaryotic Nomenclature
List of Recommended Names for bacteria of medical importance: report of the Ad Hoc Committee on Mitigating Changes in Prokaryotic Nomenclature Open
The Ad Hoc Committee on Mitigating Changes in Prokaryotic Nomenclature was recently established under the auspices of the International Committee on Systematics of Prokaryotes to address the impact of name changes of prokaryotic taxa in da…
View article: Repeated oral exposure to H5N1 influenza virus in pasteurized milk does not cause adverse responses to subsequent influenza infection
Repeated oral exposure to H5N1 influenza virus in pasteurized milk does not cause adverse responses to subsequent influenza infection Open
In March 2024, a highly pathogenic avian influenza H5N1 (HPAI) clade 2.3.4.4b virus was identified in US dairy cows, with spillover to cats, poultry, and humans. Up to 30% of commercial pasteurized milk tested contained viral genome copies…
View article: ‘What’s in a name? Fit-for-purpose bacterial nomenclature’: meeting report
‘What’s in a name? Fit-for-purpose bacterial nomenclature’: meeting report Open
Rapid and economical DNA sequencing has resulted in a revolution in phylogenomics. The impact of changes in nomenclature can be perceived as an absolute necessity of scientific rigour, coupled with the slight inconvenience of needing to re…
View article: 979 Enhancing Surgical Training Through Augmented Reality: A Pilot Study on the Use of the Microsoft HoloLens for Live-Streaming from Theatre
979 Enhancing Surgical Training Through Augmented Reality: A Pilot Study on the Use of the Microsoft HoloLens for Live-Streaming from Theatre Open
Aim Reduced theatre exposure for trainees and students is increasingly detrimental to the surgical workforce. One potential solution is live-streaming from the operating theatre - the Microsoft HoloLens, a mixed-reality headset, facilitate…
View article: Genomic analyses of Bacteroides fragilis: subdivisions I and II represent distinct species
Genomic analyses of Bacteroides fragilis: subdivisions I and II represent distinct species Open
Introduction. Bacteroides fragilis is a Gram-negative anaerobe that is a member of the human gastrointestinal microbiota and is frequently found as an extra-intestinal opportunistic pathogen. B. fragilis comprises two distinct groups – div…
View article: The potential role of molecular mimicry by the anaerobic microbiota in the aetiology of autoimmune disease
The potential role of molecular mimicry by the anaerobic microbiota in the aetiology of autoimmune disease Open
Autoimmune diseases are thought to develop as a consequence of various environmental and genetic factors, each of which contributes to dysfunctional immune responses and/or a breakdown in immunological tolerance towards native structures. …
View article: Point-Counterpoint: What’s in a Name? Clinical Microbiology Laboratories Should Use Nomenclature Based on Current Taxonomy
Point-Counterpoint: What’s in a Name? Clinical Microbiology Laboratories Should Use Nomenclature Based on Current Taxonomy Open
The mnemonic SPICE ( Serratia , Pseudomonas , indole-positive Proteus , Citrobacter , and Enterobacter ) has served as a reminder to consider when a Gram-negative organism may carry a chromosomal copy of bla ampC , with the associated risk…
View article: Bacteroides fragilis Panaroo output and gff files
Bacteroides fragilis Panaroo output and gff files Open
Gff files of all Bacteroides fragilis used and Panaroo output
View article: A tale of two habitats: Bacteroides fragilis, a lethal pathogen and resident in the human gastrointestinal microbiome
A tale of two habitats: Bacteroides fragilis, a lethal pathogen and resident in the human gastrointestinal microbiome Open
Bacteroides fragilis is an obligately anaerobic Gram-negative bacterium and a major colonizer of the human large colon where Bacteroides is a predominant genus. During the growth of an individual clonal population, an astonishing number of…
View article: Peptoids with Antibiofilm Activity against the Gram Negative Obligate Anaerobe, Fusobacterium nucleatum
Peptoids with Antibiofilm Activity against the Gram Negative Obligate Anaerobe, Fusobacterium nucleatum Open
Peptoids (oligo N-substituted glycines) are peptide analogues, which can be designed to mimic host antimicrobial peptides, with the advantage that they are resistant to proteolytic degradation. Few studies on the antimicrobial efficacy of …
View article: Longitudinal time-lapse in vivo micro-CT reveals differential patterns of peri-implant bone changes after subclinical bacterial infection in a rat model
Longitudinal time-lapse in vivo micro-CT reveals differential patterns of peri-implant bone changes after subclinical bacterial infection in a rat model Open
Subclinical infection associated with orthopedic devices can be challenging to diagnose. The goal of this study was to evaluate longitudinal, microcomputed tomography (microCT) imaging in a rat model of subclinical orthopedic device-relate…
View article: Antigenic mimicry of ubiquitin by the gut bacterium<i>Bacteroides fragilis</i>: a potential link with autoimmune disease
Antigenic mimicry of ubiquitin by the gut bacterium<i>Bacteroides fragilis</i>: a potential link with autoimmune disease Open
Summary Ubiquitin is highly conserved across eukaryotes and is essential for normal eukaryotic cell function. The bacterium Bacteroides fragilis is a member of the normal human gut microbiota, and the only bacterium known to encode a homol…
View article: Draft Genome Sequence of Propionibacterium acnes subsp. elongatum Strain Asn12
Draft Genome Sequence of Propionibacterium acnes subsp. elongatum Strain Asn12 Open
Propionibacterium acnes , a non-spore-forming anaerobic Gram-positive bacterium, has been linked to a wide range of opportunistic human infections and conditions, most notably acne vulgaris. Here, we present the draft genome sequence of P.…
View article: Novel large-scale chromosomal transfer in Bacteroides fragilis contributes to its pan-genome and rapid environmental adaptation
Novel large-scale chromosomal transfer in Bacteroides fragilis contributes to its pan-genome and rapid environmental adaptation Open
Bacteroides fragilis , an important component of the human gastrointestinal microbiota, can cause lethal extra-intestinal infection upon escape from the gastrointestinal tract. We demonstrated transfer and recombination of large chromosoma…
View article: Corrigendum: Proposal to reclassify Propionibacterium acnes type I as Propionibacterium acnes subsp. acnes subsp. nov. and Propionibacterium acnes type II as Propionibacterium acnes subsp. defendens subsp. nov.
Corrigendum: Proposal to reclassify Propionibacterium acnes type I as Propionibacterium acnes subsp. acnes subsp. nov. and Propionibacterium acnes type II as Propionibacterium acnes subsp. defendens subsp. nov. Open
Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our princi…
View article: Antisepsis of the skin before spinal surgery with povidone iodine-alcohol followed by chlorhexidine gluconate-alcohol <i>versus</i> povidone iodine-alcohol applied twice for the prevention of contamination of the wound by bacteria
Antisepsis of the skin before spinal surgery with povidone iodine-alcohol followed by chlorhexidine gluconate-alcohol <i>versus</i> povidone iodine-alcohol applied twice for the prevention of contamination of the wound by bacteria Open
Aims The aim of this study was to determine whether the sequential application of povidone iodine-alcohol (PVI) followed by chlorhexidine gluconate-alcohol (CHG) would reduce surgical wound contamination to a greater extent than PVI applie…
View article: Proposal to reclassify Propionibacterium acnes type I as Propionibacterium acnes subsp. acnes subsp. nov. and Propionibacterium acnes type II as Propionibacterium acnes subsp. defendens subsp. nov.
Proposal to reclassify Propionibacterium acnes type I as Propionibacterium acnes subsp. acnes subsp. nov. and Propionibacterium acnes type II as Propionibacterium acnes subsp. defendens subsp. nov. Open
Recently, it has been proposed that strains of Propionibacterium acnes from the type III genetic division should be classified as P. acnessubsp. elongatum subsp. nov., with strains from the type I and II divisions collectively classified a…
View article: Emergence and evolution of an international cluster of MDR<i>Bacteroides fragilis</i>isolates
Emergence and evolution of an international cluster of MDR<i>Bacteroides fragilis</i>isolates Open
An international cluster of MDR B. fragilis strains has been identified and characterized. This 'clone' may have emerged early in the evolution of division II B. fragilis strains, which was suggested by the low-complexity ERIC profiles and…
View article: Collagen Far Western blot of <i>B. fragilis</i> GSH18 wild-type and <i>cbp1</i><sup>−</sup> mutant.
Collagen Far Western blot of <i>B. fragilis</i> GSH18 wild-type and <i>cbp1</i><sup>−</sup> mutant. Open
(A) Coomassie stained gel, (B) Far Western. Lanes: (M): PageRuler™ #SM0671; (1) wild-type OMP; (2) cbp1-mutant OMP.
View article: A single chromosome assembly of <i>Bacteroides fragilis</i> strain BE1 from Illumina and MinION nanopore sequencing data
A single chromosome assembly of <i>Bacteroides fragilis</i> strain BE1 from Illumina and MinION nanopore sequencing data Open
Background Second and third generation sequencing technologies have revolutionised bacterial genomics. Short-read Illumina reads result in cheap but fragmented assemblies, whereas longer reads are more expensive but result in more complete…
View article: Multiplex Touchdown PCR for Rapid Typing of the Opportunistic Pathogen Propionibacterium acnes
Multiplex Touchdown PCR for Rapid Typing of the Opportunistic Pathogen Propionibacterium acnes Open
The opportunistic human pathogen Propionibacterium acnes is composed of a number of distinct phylogroups, designated types IA 1 , IA 2 , IB, IC, II, and III, which vary in their production of putative virulence factors, their inflammatory …