Jing Yuan
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Author Swipe
View article: Chinese expert consensus on the combined use of antiviral drugs for influenza
Chinese expert consensus on the combined use of antiviral drugs for influenza Open
Influenza is an acute respiratory infectious disease caused by influenza viruses, and it poses a serious threat to global public health. High-risk groups include the elderly, infants and young children, pregnant women, and patients with ch…
View article: The efficacy and safety of doravirine/lamivudine/tenofovir disoproxil fumarate in treatment-naïve and treatment-experienced patients with HIV
The efficacy and safety of doravirine/lamivudine/tenofovir disoproxil fumarate in treatment-naïve and treatment-experienced patients with HIV Open
We provide a short-term observational report of the efficacy and safety of DOR/3TC/TDF in routine clinical practice, further supporting its use in PWH.
View article: Effectiveness of an AI-enhanced management system for coronary heart disease (AIM-CHD): rationale and design of a single-centre, open-label, randomised, parallel-controlled trial
Effectiveness of an AI-enhanced management system for coronary heart disease (AIM-CHD): rationale and design of a single-centre, open-label, randomised, parallel-controlled trial Open
Introduction Effective secondary prevention of coronary heart disease (CHD) is often hindered by limited healthcare resources and poor patient adherence. We therefore developed an artificial intelligence (AI)-enhanced CHD management platfo…
View article: HIV-positive and HHV-8-negative primary effusion lymphoma complicated with coronary heart disease: a Case Report and literature review
HIV-positive and HHV-8-negative primary effusion lymphoma complicated with coronary heart disease: a Case Report and literature review Open
Objective This case report describes a rare instance of human immunodeficiency virus (HIV)-positive, human herpesvirus-8 (HHV-8)-negative, and Epstein-Barr virus (EBV)-negative primary effusion lymphoma (PEL) associated with pulmonary effu…
View article: Platelet dynamics and thrombocytopenia in dengue fever: A prospective cohort study from Shenzhen, China
Platelet dynamics and thrombocytopenia in dengue fever: A prospective cohort study from Shenzhen, China Open
View article: Pluronic P123/L64 Mixed Micelles as Immediate Release Systems to Enhance the Bioavailability of Praziquantel in Rats
Pluronic P123/L64 Mixed Micelles as Immediate Release Systems to Enhance the Bioavailability of Praziquantel in Rats Open
The findings of this study confirm that Pluronic P123/L64 PMMs represent a novel and promising approach for enhancing solubility and bioavailability of PZQ, both in vitro and in vivo. The development of immediate release formulations is an…
View article: Efficacy and safety of narlumosbart, an anti-RANKL monoclonal antibody, in postmenopausal women with osteoporosis: a multi-center, randomized, double-blind, placebo- and active-controlled, phased II study
Efficacy and safety of narlumosbart, an anti-RANKL monoclonal antibody, in postmenopausal women with osteoporosis: a multi-center, randomized, double-blind, placebo- and active-controlled, phased II study Open
This study was supported by Shanghai JMT-Bio Technology Co., Ltd.; National Key R&D Program of China [2021YFC2501700]; CAMS Innovation Fund for Medical Sciences (CIFMS) [2021-I2M-1-002]; National High Level Hospital Clinical Research Fundi…
View article: Iron tailing powder in cement-based composites: Evaluating filling effect from particle-size distribution
Iron tailing powder in cement-based composites: Evaluating filling effect from particle-size distribution Open
View article: Deciphering the Sequence Basis and Application of Transcriptional Initiation Regulation in Plant Genomes Through Deep Learning
Deciphering the Sequence Basis and Application of Transcriptional Initiation Regulation in Plant Genomes Through Deep Learning Open
Transcription initiation is a critical regulatory step in plant gene expression, yet its sequence determinants remain largely elusive. Here we introduce GenoRetriever , an interpretable deep learning model that deciphers the sequence basis…
View article: Efficacy and safety of <scp>JMT103</scp> in patients with bone metastases from solid tumors: A randomized Phase Ib clinical trial
Efficacy and safety of <span>JMT103</span> in patients with bone metastases from solid tumors: A randomized Phase Ib clinical trial Open
This study aimed to assess the efficacy and safety of three dosing regimens of JMT103 in patients with bone metastases from solid tumors. Eligible patients were randomly assigned to receive JMT103 subcutaneously, 120 mg every 4 weeks (Coho…
View article: Liposomal mitoxantrone monotherapy in patients with relapsed or refractory mature T‐cell and natural killer‐cell neoplasms: A phase 2, multicenter, open‐label, single‐arm trial
Liposomal mitoxantrone monotherapy in patients with relapsed or refractory mature T‐cell and natural killer‐cell neoplasms: A phase 2, multicenter, open‐label, single‐arm trial Open
Introduction The prognosis of relapsed or refractory mature T‐ and natural killer (NK)‐cell lymphoma remains dismal. Novel agents are urgently needed to improve the outcomes for this population. Methods In this phase 2, multicenter, open‐l…
View article: Platelet Dynamics Revealed the Typical Characteristics of Thrombopenia in Dengue Fever Epidemic in Shenzhen, China: A Prospective Cohort Study
Platelet Dynamics Revealed the Typical Characteristics of Thrombopenia in Dengue Fever Epidemic in Shenzhen, China: A Prospective Cohort Study Open
View article: Amphotericin B Colloidal Dispersion is Efficacious and Safe for the Management of Talaromycosis in HIV-Infected Patients: Results of a Retrospective Cohort Study in China
Amphotericin B Colloidal Dispersion is Efficacious and Safe for the Management of Talaromycosis in HIV-Infected Patients: Results of a Retrospective Cohort Study in China Open
ABCD has a clinical efficacy comparable to AmB-D, with higher symptom remission rate, lower nephrotoxicity, and lower bone marrow suppression, indicating that ABCD may be an appropriate alternative option for the clinical management of tal…
View article: Afferent loop syndrome of a patient with recurrent fever: A case report
Afferent loop syndrome of a patient with recurrent fever: A case report Open
BACKGROUND Afferent loop syndrome (ALS) is a rare complication, Aoki et al reported that the incidence of distal gastrectomy in Billroth-II is 0.3%-1.0%. The clinical manifestations of ALS are atypical, which can manifest as severe abdomin…
View article: Human immunodeficiency virus/acquired immune deficiency syndrome antiretroviral therapy initiated on the same day in treatment-naïve people with human immunodeficiency virus: A comparative study of efficacy and regimen
Human immunodeficiency virus/acquired immune deficiency syndrome antiretroviral therapy initiated on the same day in treatment-naïve people with human immunodeficiency virus: A comparative study of efficacy and regimen Open
Background: Rapid initiation of antiretroviral therapy (ART) is recommended by guidelines, however, real-world studies of same-day initiation of ART in China are limited, and an optimal treatment regimen has yet to be identified. The study…
View article: Epidemiological characteristics, complications of haemodialysis patients with end-stage diabetic nephropathy in a tertiary hospital in Guizhou, China: a cross-sectional survey
Epidemiological characteristics, complications of haemodialysis patients with end-stage diabetic nephropathy in a tertiary hospital in Guizhou, China: a cross-sectional survey Open
Introduction In China, diabetes mellitus (DM) significantly contributes to end-stage renal disease (ESRD), necessitating treatments like hemodialysis. This study investigates hemodialysis outcomes in diabetic nephropathy patients in Guizho…
View article: [Characteristics of intestinal microbiota in the acute phase of Kawasaki disease in infants and children].
[Characteristics of intestinal microbiota in the acute phase of Kawasaki disease in infants and children]. Open
There are significant differences in the structure and diversity of intestinal microbiota between children aged 0-3 years with acute KD and healthy children, suggesting that disturbances in intestinal microbiota occur during the acute phas…
View article: Evolutionary trajectory and characteristics of Mpox virus in 2023 based on a large-scale genomic surveillance in Shenzhen, China
Evolutionary trajectory and characteristics of Mpox virus in 2023 based on a large-scale genomic surveillance in Shenzhen, China Open
The global epidemic of Mpox virus (MPXV) continues, and a local outbreak has occurred in Shenzhen city since June 2023. Herein, the evolutionary trajectory and characteristics of MPXV in 2023 were analyzed using 92 MPXV sequences from the …
View article: The Myopia Prevalence and Association With Physical Activity Among Primary School Students Aged 6–12 Years: A Cross-Sectional Study in Tianjin, China
The Myopia Prevalence and Association With Physical Activity Among Primary School Students Aged 6–12 Years: A Cross-Sectional Study in Tianjin, China Open
Taking part in physical activities may be an effective way to reduce the prevalence of myopia.
View article: Design and rationale of the Comprehensive intelligent Hypertension managEment SyStem (CHESS) evaluation study: A cluster randomized controlled trial for hypertension management in primary care
Design and rationale of the Comprehensive intelligent Hypertension managEment SyStem (CHESS) evaluation study: A cluster randomized controlled trial for hypertension management in primary care Open
gov, NCT05605418.
View article: Dysregulated STAT1 gain-of-function: Pathogen-free autoimmunity and fungal infection
Dysregulated STAT1 gain-of-function: Pathogen-free autoimmunity and fungal infection Open
Inborn errors of the signal transducer and activator of transcription 1 (STAT1) result in four types of immunodeficiency disease with varying degrees of impaired STAT1 function: autosomal recessive (AR) complete STAT1 deficiency, AR partia…
View article: Effect of whole body vibration training on proprioception ：a meta-analysis
Effect of whole body vibration training on proprioception ：a meta-analysis Open
View article: Acute and persistent symptoms of COVID-19 infection in school-aged children: a retrospective study from China
Acute and persistent symptoms of COVID-19 infection in school-aged children: a retrospective study from China Open
View article: Prusogliptin ( <scp>DBPR108</scp> ) monotherapy in treatment‐naïve patients with type 2 diabetes: A randomized, double‐blind, active and placebo‐controlled, phase 3 study
Prusogliptin ( <span>DBPR108</span> ) monotherapy in treatment‐naïve patients with type 2 diabetes: A randomized, double‐blind, active and placebo‐controlled, phase 3 study Open
Aim This study aimed to assess the efficacy and safety of prusogliptin (DBPR108), a novel and highly selective dipeptidyl peptidase‐4 inhibitor, in individuals with type 2 diabetes who had not been using glucose‐lowering agents regularly f…
View article: The Intra-Host Evolution of SARS-CoV-2 After Neutralizing Antibody Therapy, Revealed by Nanopore Sequencing
The Intra-Host Evolution of SARS-CoV-2 After Neutralizing Antibody Therapy, Revealed by Nanopore Sequencing Open
Objective: In the context of two Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outbreaks involving local transmission and an international flight, we used meta-transcriptome and multi-amplicon sequencing to successfully acqu…
View article: G9a-Mediated Cholesterol Metabolism Triggers Cuproptosis to Promote Alcohol-Related Liver Disease
G9a-Mediated Cholesterol Metabolism Triggers Cuproptosis to Promote Alcohol-Related Liver Disease Open
View article: 515P A MRI-based radiomics model for predicting the response to anlotinb combined with temozolomide in recurrent malignant glioma patients
515P A MRI-based radiomics model for predicting the response to anlotinb combined with temozolomide in recurrent malignant glioma patients Open
View article: Multiplexed discrimination of SARS-CoV-2 variants via plasmonic-enhanced fluorescence in a portable and automated device
Multiplexed discrimination of SARS-CoV-2 variants via plasmonic-enhanced fluorescence in a portable and automated device Open
View article: Clinical characteristics of abruptly increased paediatric patients with Omicron BF.7 or BA.5.2 in Beijing
Clinical characteristics of abruptly increased paediatric patients with Omicron BF.7 or BA.5.2 in Beijing Open
View article: Changes in global online public interest in multiple other infectious diseases due to the COVID-19 pandemic (Preprint)
Changes in global online public interest in multiple other infectious diseases due to the COVID-19 pandemic (Preprint) Open
UNSTRUCTURED In this study, we examined the changes in global online public interest in various infectious diseases during the COVID-19 epidemic using Google Trends. To ensure research accuracy, we categorized infectious diseases into two…