Shiyu Wei
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View article: Enhancing multiple genome editing efficiency by employing CRISPR/Cas9 nickases in Erwinia billingiae QL-Z3
Enhancing multiple genome editing efficiency by employing CRISPR/Cas9 nickases in Erwinia billingiae QL-Z3 Open
Microbial genome editing is crucial for studying and optimizing enzyme functions, yet multiplex chromosomal editing remains challenging. In this study, we employed two Cas9 nickase (Cas9n) mutants, carrying D10A or H840A mutations, and sys…
View article: Karyotyping with amniotic fluid in 6,572 pregnant women and pregnancy outcomes——A single-center retrospective study
Karyotyping with amniotic fluid in 6,572 pregnant women and pregnancy outcomes——A single-center retrospective study Open
Aims To detect abnormal chromosome karyotypes in amniotic fluid cells and to explore the relationship among various prenatal diagnostic indications, karyotypes, and pregnancy outcomes. Methods The data used in this study were obtained from…
View article: An Experiment in Wayfinding in a Subway Station Based on Eye Tracker Analytical Techniques for Universal and Age-Friendly Design
An Experiment in Wayfinding in a Subway Station Based on Eye Tracker Analytical Techniques for Universal and Age-Friendly Design Open
The complexity of subway station space can impact the efficiency of passenger navigation. The subway spatial environment is a key factor affecting indoor wayfinding for pedestrians; however, the research framework that examines how various…
View article: Research on the Development Path of Rural Adolescents’ Leadership Based on the Orientation of Psychological Resilience Training: From the Perspective of Human Resource Management
Research on the Development Path of Rural Adolescents’ Leadership Based on the Orientation of Psychological Resilience Training: From the Perspective of Human Resource Management Open
This study focuses on rural youth and explores the impact mechanism of psychological resilience on leadership development from the perspective of human resource management. By analyzing the current status and challenges of leadership devel…
View article: The Evolution of Media in Image Creation from the Perspective of the Creator
The Evolution of Media in Image Creation from the Perspective of the Creator Open
This paper explores the evolution process of image creation image creation in the context of media technology changes from the perspective of a visual image creator. It reviews the transition from cel animation to computer animation and, u…
View article: Genomic characterization and antifungal properties of Paenibacillus polymyxa YF, a promising biocontrol agent against Fusarium oxysporum pathogen of codonopsis root rot
Genomic characterization and antifungal properties of Paenibacillus polymyxa YF, a promising biocontrol agent against Fusarium oxysporum pathogen of codonopsis root rot Open
Root rot, a destructive soil-borne disease, poses a significant threat to a wide range of economically important crops. Codonopsis, a high-value medicine plant, is particularly susceptible to substantial production losses caused by Fusariu…
View article: Optimization and Metabolite Profiling of Mycotoxin Enniatin B Biodegradation by Bacillus tequilensis
Optimization and Metabolite Profiling of Mycotoxin Enniatin B Biodegradation by Bacillus tequilensis Open
Fusarium avenaceum is the predominant fungal pathogen responsible for root rot in Angelica crops and poses a serious threat to their commercial quality and yield in China. This fungus produces enniatin B (ENN B), a toxin that could be a pa…
View article: Whole-genome sequencing and secondary metabolite exploration of the novel Bacillus velezensis BN with broad-spectrum antagonistic activity against fungal plant pathogens
Whole-genome sequencing and secondary metabolite exploration of the novel Bacillus velezensis BN with broad-spectrum antagonistic activity against fungal plant pathogens Open
The utilization of chemical pesticides recovers 30%−40% of food losses. However, their application has also triggered a series of problems, including food safety, environmental pollution, pesticide resistance, and incidents of poisoning. C…
View article: A Novel and Thermostable Β-Glucuronidase from Thermobacillus Composti Precisely Hydrolyzes Glycyrrhizin into Glycyrrhetinic Acid
A Novel and Thermostable Β-Glucuronidase from Thermobacillus Composti Precisely Hydrolyzes Glycyrrhizin into Glycyrrhetinic Acid Open
View article: Light-Driven Release of 6ppd and Formation of 6ppd-Q from Tire Rubber Particles: Mechanisms and Cytotoxicity
Light-Driven Release of 6ppd and Formation of 6ppd-Q from Tire Rubber Particles: Mechanisms and Cytotoxicity Open
View article: Research on the application of big data technology in China’s tax administration
Research on the application of big data technology in China’s tax administration Open
With the advent of the big data era, the amount of various types of data is growing exponentially. Technologies such as big data, cloud computing, and artificial intelligence have achieved unprecedented development speed, and countries, re…
View article: LncRNA FAISL Inhibits Calpain 2‐Mediated Proteolysis of FAK to Promote Progression and Metastasis of Triple Negative Breast Cancer
LncRNA FAISL Inhibits Calpain 2‐Mediated Proteolysis of FAK to Promote Progression and Metastasis of Triple Negative Breast Cancer Open
Triple negative breast cancer (TNBC) is the most aggressive subtype in breast tumors. When re‐analyzing TCGA breast cancer dataset, we found cell adhesion molecules are highly enriched in differentially expressed genes in TNBC samples, amo…
View article: Engineering Cu-Mofs with Tailored Dimensions and Enhanced Proton Conductivity Via Ph-Controlled Synthesis
Engineering Cu-Mofs with Tailored Dimensions and Enhanced Proton Conductivity Via Ph-Controlled Synthesis Open
View article: Introducing Sulfonic Acid Polymers into Mof Nanochannels for Ultra-High Ba2+ Adsorption Capacity and Proton Conductivity
Introducing Sulfonic Acid Polymers into Mof Nanochannels for Ultra-High Ba2+ Adsorption Capacity and Proton Conductivity Open
View article: Strengthening of Plasma Sprayed Alcocrfeni High-Entropy Alloy Coatings by Laser Remelting
Strengthening of Plasma Sprayed Alcocrfeni High-Entropy Alloy Coatings by Laser Remelting Open
View article: High performance of membrane capacitive deionization with ZnS/g-C3N4 composite electrodes
High performance of membrane capacitive deionization with ZnS/g-C3N4 composite electrodes Open
Capacitive deionization (CDI) is considered a promising technology for desalination of sea or brackish water. In this study, a ZnS/g-C3N4 composite was synthesized through a one-step high-temperature method and used as the main material to…
View article: To Marry or To Write?—Sheng Qinxian and Her (Screen) Writing in 1940s Shanghai
To Marry or To Write?—Sheng Qinxian and Her (Screen) Writing in 1940s Shanghai Open
During the Japanese occupation of Shanghai, writer-translator Sheng Qinxian (1921–2017) joined the script division of the Incorporated Film Studio of China and wrote the screenplays of three successful films: The Honourable Beggar (义丐 1944…
View article: Recent Developments on the Removal of Zinc from Electric Arc Furnace Dust by Using Microwave Heating
Recent Developments on the Removal of Zinc from Electric Arc Furnace Dust by Using Microwave Heating Open
Electric arc furnace dust (EAFD) is a hazardous by-product of steel production. As global steel output increases, substantial amounts of EAFD are produced, which causes significant environmental issues. EAFD contains amounts of Fe and Zn, …
View article: An Encounter in Hong Kong Streets, 60 Years Apart
An Encounter in Hong Kong Streets, 60 Years Apart Open
Hong Kong has a history punctuated by waves of immigrants and influxes of expats, especially during years of wars, famine, and drastic social changes. The wide wealth gap among different classes contributes to the diverse cityscapes within…
View article: A Novel Method of Si and Si3N4 Powder Resources Recycling: Cold Bonding Briquettes
A Novel Method of Si and Si3N4 Powder Resources Recycling: Cold Bonding Briquettes Open
Silicon nitride (Si3N4) and silicon powder (Si) are two kinds of harmful solid waste in industrial production. As an environmental and low-consumption method, the cold-bonding technique is a novel method to utilize the problem of powder re…
View article: Efficacy of the WINROP algorithm for retinopathy of prematurity screening in Southern China
Efficacy of the WINROP algorithm for retinopathy of prematurity screening in Southern China Open
AIM: To evaluate the predicting efficacy of severe retinopathy of prematurity (ROP) by the WINROP algorithm (http://winrop.com) in Southern China. METHODS: All preterm infants with the gestational age (GA) less than 32wk were included. The…
View article: The Memory of Colour: Havana Divas, Cantonese Opera
The Memory of Colour: Havana Divas, Cantonese Opera Open