Shengwen Long
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View article: KCTD10 inhibits lung cancer metastasis and angiogenesis via ubiquitin-mediated β-catenin degradation
KCTD10 inhibits lung cancer metastasis and angiogenesis via ubiquitin-mediated β-catenin degradation Open
Lung cancer remains a critical global health concern, characterized by the highest incidence and mortality rates among all cancers. Due to its heterogeneity and complexity, the molecular mechanism underlying lung cancer occurrence and prog…
View article: AP-2α decreases TMZ resistance of recurrent GBM by downregulating MGMT expression and improving DNA damage
AP-2α decreases TMZ resistance of recurrent GBM by downregulating MGMT expression and improving DNA damage Open
AP-2α activation by gene overexpression or RA treatment reveals the suppressive effects on glioma relapse, providing a novel therapeutic strategy against malignant refractory gliomas.
View article: Epigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression
Epigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression Open
View article: Corrigendum: Purification and Identification of miRNA Target Sites in Genome Using DNA Affinity Precipitation
Corrigendum: Purification and Identification of miRNA Target Sites in Genome Using DNA Affinity Precipitation Open
[This corrects the article DOI: 10.3389/fgene.2019.00778.].
View article: Tumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma
Tumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma Open
View article: Purification and Identification of miRNA Target Sites in Genome Using DNA Affinity Precipitation
Purification and Identification of miRNA Target Sites in Genome Using DNA Affinity Precipitation Open
Combination with genomic DNA is one of the important ways for microRNAs (miRNAs) to perform biological processes. However, because of lack of an experimental method, the identified genomic sites targeted by microRNA were only located in th…
View article: Tumor Necrosis Factor α-Induced Protein 1 as a Novel Tumor Suppressor Through Selectively Downregulation of CSNK2B Blocks Nuclear Factor-κB Activation in Hepatocellular Carcinoma
Tumor Necrosis Factor α-Induced Protein 1 as a Novel Tumor Suppressor Through Selectively Downregulation of CSNK2B Blocks Nuclear Factor-κB Activation in Hepatocellular Carcinoma Open
View article: Neuroglobin Regulates Wnt/β-Catenin and NFκB Signaling Pathway through Dvl1
Neuroglobin Regulates Wnt/β-Catenin and NFκB Signaling Pathway through Dvl1 Open
Neuroglobin is an endogenous neuroprotective protein, but the underlying neuroprotective mechanisms remain to be elucidated. Our previous yeast two-hybrid screening study identified that Dishevelled-1, a key hub protein of Wnt/β-Catenin si…