Explanipedia

Electrocatalytic Multicomponent Cascade Cross-Coupling for Synthesis of Chalcogenosulfonates Open

Zhiheng Zhao, Hongyan Yan, Yaqin Zhou, Wei Xue, Lijun Gu , et al. · 2024

An method for the electrochemical synthesis of chalcogenosulfonates via a tandem multi-component reaction has been developed. This method is performed in an undivided cell without the requirement of external oxidants, acids, and transition…

Application of chiral recyclable catalysts in asymmetric catalysis Open

GuiPing Han, WenQi Ren, Shengyong Zhang, Zhenyu Zuo, Wei He · 2024

Chiral drugs hold a significant position within the contemporary pharmaceutical market, and the chiral catalysts play a crucial role in their synthesis.

CCDC 2222101: Experimental Crystal Structure Determination Open

Yu‐Jun Bai, Xueying Wang, Si-Kai Zhu, Xiaohui Zheng, Shengyong Zhang , et al. · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

DBU-catalyzed Michael additions of bulky glycine imine to β-arylfuryl substituted α,β-unsaturated esters Open

Mei-Ling Cheng, Xueying Wang, Yu‐Jun Bai, Si-Kai Zhu, Shengyong Zhang , et al. · 2023

DBU-catalyzed Michael reactions between tert-butyl 2-((diphenylmethylene) amino)acetate and simple β-substituted α,β-unsaturated esters have been achieved in high yields (up to 95% yield) and diastereoselectivties (up to 99:1 dr) in…

CCDC 2133196: Experimental Crystal Structure Determination Open

Yu‐Jun Bai, Mei‐Ling Cheng, Xiaohui Zheng, Shengyong Zhang, Pingan Wang · 2022

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2089780: Experimental Crystal Structure Determination Open

Zhuang Nie, Song Liu, Tonglin Wang, Zhanhong Shen, Huifang Nie , et al. · 2022

CCDC 2122207: Experimental Crystal Structure Determination Open

Zhuang Nie, Song Liu, Tonglin Wang, Zhanhong Shen, Huifang Nie , et al. · 2022

CCDC 1921899: Experimental Crystal Structure Determination Open

Qi Xue, Fuqiang Bi, Lianjie Zhai, Tao Guo, Jiarong Zhang , et al. · 2021

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1921898: Experimental Crystal Structure Determination Open

Qi Xue, Fuqiang Bi, Lianjie Zhai, Tao Guo, Jiarong Zhang , et al. · 2021

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1921897: Experimental Crystal Structure Determination Open

Qi Xue, Fuqiang Bi, Lianjie Zhai, Tao Guo, Jiarong Zhang , et al. · 2021

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2114009: Experimental Crystal Structure Determination Open

Yu‐Jun Bai, Xiaomu Hu, Yajun Bai, Xiaohui Zheng, Shengyong Zhang , et al. · 2021

CCDC 2057100: Experimental Crystal Structure Determination Open

Yu‐Jun Bai, Xiaomu Hu, Yajun Bai, Xiaohui Zheng, Shengyong Zhang , et al. · 2021

CCDC 2035935: Experimental Crystal Structure Determination Open

Aiyun Liu, Tiantian Guo, Shuangshuang Zhang, Yang Han, Qi Zhang , et al. · 2021

CCDC 2035936: Experimental Crystal Structure Determination Open

Aiyun Liu, Tiantian Guo, Shuangshuang Zhang, Han Yang, Qi Zhang , et al. · 2021

CCDC 2035937: Experimental Crystal Structure Determination Open

Aiyun Liu, Tiantian Guo, Shuangshuang Zhang, Yang Han, Qi Zhang , et al. · 2021

DBU-catalyzed Michael addition of bulky glycine imine to α,β-unsaturated isoxazoles and pyrazolamides Open

Yu‐Jun Bai, Mei-Ling Cheng, Xiaomu Hu, Yajun Bai, Xiaohui Zheng , et al. · 2021

A DBU-catalyzed Michael additions of several pronucleophiles with high p K a values including bulky glycine imines, α-tetra-lone, 1-methyl-2-indolone and nitroalkanes to α,β-unsaturated isoxazoles and pyrazolamides have been realized in TH…

CCDC 2034258: Experimental Crystal Structure Determination Open

Lin Yao, Haixia Ma, Zhuang Nie, Huifang Nie, Dongxu Zhang , et al. · 2020

CCDC 1958390: Experimental Crystal Structure Determination Open

Qi Xue, Fuqiang Bi, Jun-Lin Zhang, Zijun Wang, Lianjie Zhai , et al. · 2020

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1958391: Experimental Crystal Structure Determination Open

Qi Xue, Fuqiang Bi, Jun-Lin Zhang, Zijun Wang, Lianjie Zhai , et al. · 2020

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

A Family of Energetic Materials Based on 1,2,4-Oxadiazole and 1,2,5-Oxadiazole Backbones With Low Insensitivity and Good Detonation Performance Open

Qi Xue, Fuqiang Bi, Jun-Lin Zhang, Zijun Wang, Lianjie Zhai , et al. · 2020

Design and synthesis of new compounds with both high detonation performances and good safety properties have always been a formidable task in the field of energetic materials. By introducing -ONO₂ and -NHNO₂ moieties …

Advances in the Synthesis and Properties of the Isofurazan Energetic Compounds Open

Qi Xue, Fuqiang Bi, Jiarong Zhang, Junlin Zhang, Bozhou Wang , et al. · 2019

Isofurazan is composed of 1,3,4-oxadiazole and 1,2,4-oxadiazole, and the isofurazan compounds have gained considerable prominence as energetic compounds.This review focues on the two major classes of isofurazan energetic compounds and thei…

A bio-inspired synthesis of hybrid flavonoids from 2-hydroxychalcone driven by visible light Open

Yu-Qi Gao, Yi Hou, Li Zhu, Guzhou Chen, Dongyang Xu , et al. · 2019

An efficient protocol for the synthesis of hybrid flavonoids was achieved via a bio-inspired tandem reaction of 2-hydroxychalcone with various nucleophiles.

Drug–Drug Interactions Between PA-824 and Darunavir Based on Pharmacokinetics in Rats by LC–MS-MS Open

Libin Wang, Jun Zhao, Ruitao Zhang, Le Mi, Xin Shen , et al. · 2018

Currently, patients with co-infection with HIV and tuberculosis are treated with more than one drug. PA-824 a new chemical entity and a member of a class of compounds known as nitroimidazo-oxazines, has significant antituberculosis activit…

CCDC 1424455: Experimental Crystal Structure Determination Open

Lin Yao, Huifang Nie, Dongxu Zhang, Libin Wang, Yuhao Zhang , et al. · 2018

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1424454: Experimental Crystal Structure Determination Open

Lin Yao, Huifang Nie, Dongxu Zhang, Libin Wang, Yuhao Zhang , et al. · 2018

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1438410: Experimental Crystal Structure Determination Open

Lin Yao, Huifang Nie, Dongxu Zhang, Libin Wang, Yuhao Zhang , et al. · 2018

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Fluorescent probes guided by a new practical performance regulation strategy to monitor glutathione in living systems Open

Mengyao She, Zhaohui Wang, Tianyou Luo, Bing Yin, Ping Liu , et al. · 2018

A practical regulation strategy for the design of glutathione specific probes and their application in living systems.

Salidroside, a scavenger of ROS, enhances the radioprotective effect of Ex-RAD® via a p53-dependent apoptotic pathway Open

Feng Tian, Libin Wang, Nan Zhou, Chang Liu, Jiahui Cui , et al. · 2017

Salidroside (Sal), the predominant component of a Chinese medicinal herb, Rhodiola rosea L., has become an attractive bioagent due to its significant anti-radiation, antioxidant and immune adjustment effects. We explored the radioprotectiv…

Design strategies and progress on xanthene-based fluorescent probe for metal ions Open

Siyue Ma, Yaqi Wang, Mengyao She, Shen Wang, Zheng Yang , et al. · 2017

Metal ions play critical roles in numerous fundamental life processes. Hence, there is a great need to effectively monitor and image metal ions. Fluorescent probes are one of the most effective methods for measuring metal ions. In general,…

Targeting the apoptotic Mcl-1-PUMA interface with a dual-acting compound Open

Jiyuan Liu, Zhen Tian, Nan Zhou, Xueying Liu, Chenyi Liao , et al. · 2017

Despite intensive efforts in the search for small molecules with anti-cancer activity, it remains challenging to achieve both high effectiveness and safety, since many agents lack the selectivity to only act on cancer cells. The interface …

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