Shengze Zhang
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View article: DISC1 Protects Against Zika Virus Infection and Long-Term Neurological Damage Through AMPK-mTOR-Mediated Autophagy
DISC1 Protects Against Zika Virus Infection and Long-Term Neurological Damage Through AMPK-mTOR-Mediated Autophagy Open
View article: Association between DDT or its byproducts and T2DM: a systematic review and meta-analysis
Association between DDT or its byproducts and T2DM: a systematic review and meta-analysis Open
Background Currently, type 2 diabetes mellitus (T2DM) is among the fastest-growing global health emergencies of the century. Emerging evidence from epidemiological studies suggests a potential positive association between exposure to dichl…
View article: Association between DDT or its byproducts and T2DM: a systematic review and meta-analysis
Association between DDT or its byproducts and T2DM: a systematic review and meta-analysis Open
View article: Glucosidase alpha neutral C promotes influenza virus replication by inhibiting proteosome-dependent degradation of hemagglutinin
Glucosidase alpha neutral C promotes influenza virus replication by inhibiting proteosome-dependent degradation of hemagglutinin Open
The H7N9 influenza virus poses a significant threat to human health, and the mechanism by which it infects humans remains incompletely understood. Our investigation has unveiled significant insights into the role of glucosidase alpha, neut…
View article: Year-round infectome profiling of acute febrile respiratory illness unveiled complex epidemiological dynamics postlifting of COVID-19 restrictions
Year-round infectome profiling of acute febrile respiratory illness unveiled complex epidemiological dynamics postlifting of COVID-19 restrictions Open
View article: RNA-Seq Reveals Transcriptome Changes Following Zika Virus Infection in Fetal Brains in c-Flip Knockdown Mice
RNA-Seq Reveals Transcriptome Changes Following Zika Virus Infection in Fetal Brains in c-Flip Knockdown Mice Open
The FADD-like interleukin-1β converting enzyme (FLICE)-inhibitory protein (c-FLIP) plays a crucial role in various biological processes, including apoptosis and inflammation. However, the complete transcriptional profile altered by the c-F…
View article: ZIKV induces P62-mediated autophagic degradation of TRAF6 through TRAF6-NS1 interaction
ZIKV induces P62-mediated autophagic degradation of TRAF6 through TRAF6-NS1 interaction Open
View article: A broad-spectrum multiepitope vaccine against seasonal influenza A and B viruses in mice
A broad-spectrum multiepitope vaccine against seasonal influenza A and B viruses in mice Open
View article: c-FLIP facilitates ZIKV infection by mediating caspase-8/3-dependent apoptosis
c-FLIP facilitates ZIKV infection by mediating caspase-8/3-dependent apoptosis Open
c-FLIP functions as a dual regulator of apoptosis and inflammation, yet its implications in Zika virus (ZIKV) infection remain partially understood, especially in the context of ZIKV-induced congenital Zika syndrome (CZS) where both apopto…
View article: Year-Round Infectome Profiling of Acute Febrile Respiratory Illness Unveiled Multi-Pathogen Dynamics Post-Lifting of COVID-19 Restrictions
Year-Round Infectome Profiling of Acute Febrile Respiratory Illness Unveiled Multi-Pathogen Dynamics Post-Lifting of COVID-19 Restrictions Open
View article: Rna-Seq Reveals Transcriptome Changes in Fetal Head Following C-Flip Knockdown
Rna-Seq Reveals Transcriptome Changes in Fetal Head Following C-Flip Knockdown Open
View article: ZIKV infection differentially affects the transcriptional profiles in HTR8 and U251 cells
ZIKV infection differentially affects the transcriptional profiles in HTR8 and U251 cells Open
The mechanism by which Zika virus (ZIKV) causes severe birth defects in pregnant women remains unclear. Cell tropisms in placenta and brain play a crucial role in ZIKV pathogenesis, leading to congenital Zika syndrome (CZS). To identify th…
View article: Dysbiosis of oropharyngeal microbiome and antibiotic resistance in hospitalized COVID‐19 patients
Dysbiosis of oropharyngeal microbiome and antibiotic resistance in hospitalized COVID‐19 patients Open
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic is ongoing and multiple studies have elucidated its pathogenesis, however, the related‐ microbiome imbalance caused by SARS‐CoV‐2 is still not clear. In this study, …
View article: Pre-existing humoral immunity to low pathogenic human coronaviruses exhibits limited cross-reactive antibodies response against SARS-CoV-2 in children
Pre-existing humoral immunity to low pathogenic human coronaviruses exhibits limited cross-reactive antibodies response against SARS-CoV-2 in children Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes asymptomatic or mild symptoms, even rare hospitalization in children. A major concern is whether the pre-existing antibodies induced by low pathogenic human coro…