Sheryl Lynch
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View article: Frailty Snapshot in the Emergency Department: Surveying the Needs of Older Adults
Frailty Snapshot in the Emergency Department: Surveying the Needs of Older Adults Open
Background Older adults presenting to Emergency Departments (EDs) with frailty often have complex needs not fully addressed by ED care models. Evidence shows these patients frequently experience gaps in basic care, including support for da…
View article: Evaluation of <i>CYP2C19</i> Clinical Decision Support Alerts to Guide P2Y<sub>12</sub> Inhibitor Prescribing
Evaluation of <i>CYP2C19</i> Clinical Decision Support Alerts to Guide P2Y<sub>12</sub> Inhibitor Prescribing Open
P2Y 12 inhibitor selection involves numerous factors, including CYP2C19 genetics, since evidence demonstrates reduced clopidogrel efficacy in patients with decreased or no function CYP2C19 variants. In 2020, Indiana University health embed…
View article: Development of a Multifaceted Program for Pharmacogenetics Adoption at an Academic Medical Center: Practical Considerations and Lessons Learned
Development of a Multifaceted Program for Pharmacogenetics Adoption at an Academic Medical Center: Practical Considerations and Lessons Learned Open
In 2019, Indiana University launched the Precision Health Initiative to enhance the institutional adoption of precision medicine, including pharmacogenetics (PGx) implementation, at university‐affiliated practice sites across Indiana. The …
View article: Implementing a pragmatic clinical trial to tailor opioids for chronic pain on behalf of the <scp>IGNITE ADOPT PGx</scp> investigators
Implementing a pragmatic clinical trial to tailor opioids for chronic pain on behalf of the <span>IGNITE ADOPT PGx</span> investigators Open
Chronic pain is a prevalent condition with enormous economic burden. Opioids such as tramadol, codeine, and hydrocodone are commonly used to treat chronic pain; these drugs are activated to more potent opioid receptor agonists by the hepat…
View article: Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the <scp>IGNITE ADOPT PGx</scp> investigators
Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the <span>IGNITE ADOPT PGx</span> investigators Open
Opioid prescribing for postoperative pain management is challenging because of inter‐patient variability in opioid response and concern about opioid addiction. Tramadol, hydrocodone, and codeine depend on the cytochrome P450 2D6 (CYP2D6) e…
View article: White Paper on Resilience Management Guidelines for Critical Infrastructures. From theory to practice by engaging end-users: concepts, interventions, tools and methods
White Paper on Resilience Management Guidelines for Critical Infrastructures. From theory to practice by engaging end-users: concepts, interventions, tools and methods Open
Introduction: This White Paper outlines a pathway towards the integration of the European Resilience Management Guidelines (ERMG) developed as part of the work performed by five Horizon 2020 DRS-07-2014 Projects. Resilience management addr…
View article: Effect of Covered Metallic Stents Compared With Plastic Stents on Benign Biliary Stricture Resolution
Effect of Covered Metallic Stents Compared With Plastic Stents on Benign Biliary Stricture Resolution Open
clinicaltrials.gov Identifier: NCT01221311.