Explanipedia

Gut microbe-derived aromatic trace amines mediate individual variability in response to herbal medicine CDD-2101 for functional constipation Open

Shi-Fa Ruan, Yaqi Li, Ziwan Ning, Yunlyu Li, Qin Liu , et al. · 2025

Explore the Anti-Acne Mechanism of Licorice Flavonoids Based on Metabonomics and Microbiome Open

Shi-Fa Ruan, Yi Hu, Wenfeng Wu, Qunqun Du, Zhuxian Wang , et al. · 2022

Acne vulgaris is one of the most common inflammatory dermatoses in dermatological practice and can affect any gender or ethnic group. Although in previous studies, we had found that licorice flavonoids (LCF) play an anti-acne role by inhib…

Potential role of mTORC1 and the PI3K-Akt pathway in anti-acne properties of licorice flavonoids Open

Shi-Fa Ruan, Shijian Xiang, Wenfeng Wu, Siwei Cao, Qunqun Du , et al. · 2020

Altered metabolites in guinea pigs with allergic asthma after acupoint sticking therapy: New insights from a metabolomics approach Open

Shijian Xiang, Meng-Heng Li, Chi-On Chan, Qun Shen, Sibao Chen , et al. · 2018

Isoliquiritigenin suppresses human melanoma growth by targeting miR-301b/LRIG1 signaling Open

Shijian Xiang, Huoji Chen, Xiaojun Luo, Baichao An, Wenfeng Wu , et al. · 2018

Glycyrrhiza flavonoids and its major component, licochalcone A, inhibit melanogenesis through MAPK/ERK pathway by activating ERK phosphorylation Open

Jun-Hui Hong, Siwei Cao, Shijian Xiang, Shi-Fa Ruan, Baichao An , et al. · 2018

Capsaicin reverses the inhibitory effect of licochalcone A/β-Arbutin on tyrosinase expression in b16 mouse melanoma cells Open

Jun-Hui Hong, Huoji Chen, Shijian Xiang, Siwei Cao, Baichao An , et al. · 2018

B16 mouse melanoma cells were treated with the tyrosinase inhibitors licochalcone A and β-arbutin, alone or in combination with capsaicin, an alkaloid found in peppers. Cytotoxicity, melanin content, and tyrosinase activity and expression …

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