Yanxia Shi
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View article: Psilocybin induces sex- and context-specific recruitment of the stress axis
Psilocybin induces sex- and context-specific recruitment of the stress axis Open
Following decades of prohibition, psychedelic drugs have reemerged as promising therapeutics for stress-related conditions, including depression and post-traumatic stress disorder. Still, their impact on stress-related brain regions and th…
View article: Online food delivery under extreme heat: a case study of Beijing
Online food delivery under extreme heat: a case study of Beijing Open
The environmental changes, such as global warming, are expected to impact people’s health in various ways, including their diet. Quantifying these effects is challenging due to the high cost and limited scalability of traditional survey me…
View article: Impact of the Mean Radiant Temperature (Tmrt) on Outdoor Thermal Comfort Based on Urban Renewal: A Case Study of the Panjiayuan Antique Market in Beijing, China
Impact of the Mean Radiant Temperature (Tmrt) on Outdoor Thermal Comfort Based on Urban Renewal: A Case Study of the Panjiayuan Antique Market in Beijing, China Open
Like other mega cities in China, Beijing is undergoing a large-scale urban renewal process. However, in the context of global warming and the goal of promoting human health and well-being, urban renewal should follow the principle of minim…
View article: Diurnal Release of Airborne Pathogen Spores in Greenhouses via the Synergistic Effects of Relative Humidity and Wind
Diurnal Release of Airborne Pathogen Spores in Greenhouses via the Synergistic Effects of Relative Humidity and Wind Open
The occurrence of diseases during greenhouse vegetable cultivation is becoming increasingly severe. Humidity and wind are important factors affecting the spread of many pathogenic fungal spores, but it remains difficult to explain the phen…
View article: Coating Seeds with Paenibacillus polymyxa ZF129 Microcapsule Suspension Enhanced Control Effect on Fusarium Root Rot and Promoted Seedling Growth in Cucumber
Coating Seeds with Paenibacillus polymyxa ZF129 Microcapsule Suspension Enhanced Control Effect on Fusarium Root Rot and Promoted Seedling Growth in Cucumber Open
Fusarium root rot, a destructive soil-borne fungal disease, necessitates eco-friendly biocontrol strategies. This study developed a microbial seed-coating approach using the antagonistic strain Paenibacillus polymyxa ZF129, formulated into…
View article: Antidepressants reactivate developmental plasticity through remodeling of extracellular matrix
Antidepressants reactivate developmental plasticity through remodeling of extracellular matrix Open
Selective serotonin reuptake inhibitors (SSRIs) are widely used to treat mood and anxiety disorders, yet their molecular mechanisms of action remain poorly understood. Here, we show that chronic treatment with the SSRI fluoxetine reinstate…
View article: A critical role of protein damage response in mediating cancer drug resistance
A critical role of protein damage response in mediating cancer drug resistance Open
Multidrug resistance (MDR) frequently occurs during cancer therapy and remains a major obstacle for the cure of most cancers( 1, 2 ). Drug resistance could exist intrinsically or be acquired by drug treatment( 3–5 ), yet factors that regul…
View article: Deciphering Differences in Microbial Community Diversity between Clubroot-Diseased and Healthy Soils
Deciphering Differences in Microbial Community Diversity between Clubroot-Diseased and Healthy Soils Open
Clubroot (Plasmodiophora brassicae) is an important soilborne disease that causes severe damage to cruciferous crops in China. This study aims to compare the differences in chemical properties and microbiomes between healthy and clubroot-d…
View article: The occurrence of clubroot in cruciferous crops correlates with the chemical and microbial characteristics of soils
The occurrence of clubroot in cruciferous crops correlates with the chemical and microbial characteristics of soils Open
Clubroot disease, caused by Plasmodiophora brassicae , is a serious soil-borne disease in Brassica crops worldwide. It seriously occurs in conducive soils of southern China, while never happens in some areas of northern China with suppress…
View article: Transcriptome Analysis Reveals the Involvement of Mitophagy and Peroxisome in the Resistance to QoIs in Corynespora cassiicola
Transcriptome Analysis Reveals the Involvement of Mitophagy and Peroxisome in the Resistance to QoIs in Corynespora cassiicola Open
Quinone outside inhibitor fungicides (QoIs) are crucial fungicides for controlling plant diseases, but resistance, mainly caused by G143A, has been widely reported with the high and widespread use of QoIs. However, two phenotypes of Coryne…
View article: Rapid Detection and Quantification of Viable Cells of Pectobacterium brasiliense Using Propidium Monoazide Combined with Real-Time PCR
Rapid Detection and Quantification of Viable Cells of Pectobacterium brasiliense Using Propidium Monoazide Combined with Real-Time PCR Open
Pectobacterium brasiliense (Pbr) has caused significant economic losses in major vegetable production areas in Northern China by causing bacterial soft rot in cash crops such as potatoes and cucumbers. This study aimed to establish a PMA-q…
View article: Seed Pelleting with Gum Arabic-Encapsulated Biocontrol Bacteria for Effective Control of Clubroot Disease in Pak Choi
Seed Pelleting with Gum Arabic-Encapsulated Biocontrol Bacteria for Effective Control of Clubroot Disease in Pak Choi Open
Clubroot is one of the most serious soil-borne diseases on crucifer crops worldwide. Seed treatment with biocontrol agents is an effective and eco-friendly way to control clubroot disease. However, there is a big challenge to inoculating t…
View article: Asiatic acid ameliorates rifampicin‐ and isoniazid‐induced liver injury in vivo by regulating sphingolipid metabolism and mitogen‐activated protein kinase signalling pathways
Asiatic acid ameliorates rifampicin‐ and isoniazid‐induced liver injury in vivo by regulating sphingolipid metabolism and mitogen‐activated protein kinase signalling pathways Open
In this study, we aimed to determine whether asiatic acid (AA) exerts any therapeutic effects on rifampicin (RFP)‐ and isoniazid (INH)‐induced liver injury and elucidate the underlying mechanisms. Briefly, liver injury in mice was induced …
View article: Effect of temperature and humidity on dynamics and transmission of Pseudomonas amygdali pv. lachrymans aerosols
Effect of temperature and humidity on dynamics and transmission of Pseudomonas amygdali pv. lachrymans aerosols Open
Cucumber angular leaf spot (ALS) disease, caused by Pseudomonas amygdali pv. lachrymans (Pal) , is an emerging disease with a high incidence that causes severe damage to cucumber worldwide. Bacterial aerosols play a crucial role in the epi…
View article: Loss of monoacylglycerol O-acyltransferase 2 can be compensated for by diacylglycerol O-acyltransferases 1 and 2 resulting in a negligible influence on mammary cancer development found in a mouse model and verified in human tissues
Loss of monoacylglycerol O-acyltransferase 2 can be compensated for by diacylglycerol O-acyltransferases 1 and 2 resulting in a negligible influence on mammary cancer development found in a mouse model and verified in human tissues Open
Background : Dietary fat absorption involves the re-esterification of digested triacylglycerol in the enterocytes, it is a biological process catalyzed by monoacylglycerol O-acyltransferase 2 (MOGAT2, aka MGAT2), which is highly expressed …
View article: The calcium cyanamide and polyethylene blocks the secondary transmission and infection of vegetable leaf diseases
The calcium cyanamide and polyethylene blocks the secondary transmission and infection of vegetable leaf diseases Open
Continuous cropping obstacles, especially soil-borne diseases can cause serious harm to agricultural production and limit the sustainable development of modern agriculture. However, Corynespora blight is an important air-borne disease on c…
View article: Temperature and Humidity Regulate Sporulation of Corynespora cassiicola That Is Associated with Pathogenicity in Cucumber (Cucumis sativus L.)
Temperature and Humidity Regulate Sporulation of Corynespora cassiicola That Is Associated with Pathogenicity in Cucumber (Cucumis sativus L.) Open
Cucumber target leaf spot, caused by Corynespora cassiicola, is an emerging disease with a high incidence that causes severe damage to cucumbers on a global scale. Therefore, efforts need to be undertaken to limit the spread and infection …
View article: Rapid Quantification of Infectious Cucumber green mottle mosaic virus in Watermelon Tissues by PMA Coupled with RT-qPCR
Rapid Quantification of Infectious Cucumber green mottle mosaic virus in Watermelon Tissues by PMA Coupled with RT-qPCR Open
Cucumber green mottle mosaic virus (CGMMV) belongs to the Tobamovirus genus and is an important quarantine virus of cucurbit crops. Seedborne transmission is one of the principal modes for CGMMV spread, and effective early detection is hel…
View article: Comparative genomics provides insights into the potential biocontrol mechanism of two Lysobacter enzymogenes strains with distinct antagonistic activities
Comparative genomics provides insights into the potential biocontrol mechanism of two Lysobacter enzymogenes strains with distinct antagonistic activities Open
Lysobacter enzymogenes has been applied as an abundant beneficial microorganism to control plant disease; however, most L. enzymogenes strains have been mainly reported to control fungal diseases, not bacterial diseases. In this study, two…
View article: Comparative Genomics Insights into a Novel Biocontrol Agent Paenibacillus peoriae Strain ZF390 against Bacterial Soft Rot
Comparative Genomics Insights into a Novel Biocontrol Agent Paenibacillus peoriae Strain ZF390 against Bacterial Soft Rot Open
Bacterial soft rot, caused by Pectobacterium brasiliense, can infect several economically important horticultural crops. However, the management strategies available to control this disease are limited. Plant-growth-promoting rhizobacteria…
View article: Development of a Real-Time Quantitative PCR Assay for the Specific Detection of Bacillus velezensis and Its Application in the Study of Colonization Ability
Development of a Real-Time Quantitative PCR Assay for the Specific Detection of Bacillus velezensis and Its Application in the Study of Colonization Ability Open
Bacillus velezensis is a widely used biocontrol agent closely related to B. amyloliquefaciens, and the two species cannot be distinguished by universal primers that are currently available. The study aimed to establish a rapid, specific de…
View article: An Improved Method for Quantification of Viable Fusarium Cells in Infected Soil Products by Propidium Monoazide Coupled with Real-Time PCR
An Improved Method for Quantification of Viable Fusarium Cells in Infected Soil Products by Propidium Monoazide Coupled with Real-Time PCR Open
Fusarium is a soil-borne pathogen that causes root rot disease in cucumber. To date, quantitative real-time PCR (qPCR) is a common tool to detect the content of Fusarium in soil. However, qPCR cannot distinguish between viable and nonviabl…
View article: Association of a Novel DOCK2 Mutation-Related Gene Signature With Immune in Hepatocellular Carcinoma
Association of a Novel DOCK2 Mutation-Related Gene Signature With Immune in Hepatocellular Carcinoma Open
Hepatocellular carcinoma (HCC) is a malignant tumor with high morbidity and mortality worldwide. Many studies have shown that dedicator of cytokinesis 2 (DOCK2) has a crucial role as a prognostic factor in various cancers. However, the pot…
View article: Fine mapping and candidate gene analysis of gummy stem blight resistance in cucumber stem
Fine mapping and candidate gene analysis of gummy stem blight resistance in cucumber stem Open
Gummy stem blight (GSB) is a serious fungal disease caused by Didymella bryoniae , that affects cucumber yield and quality worldwide. However, no GSB resistant genes have been identified in cucumber cultivars. In this study, the wild cucum…
View article: Comparative Genomics Assisted Functional Characterization of Rahnella aceris ZF458 as a Novel Plant Growth Promoting Rhizobacterium
Comparative Genomics Assisted Functional Characterization of Rahnella aceris ZF458 as a Novel Plant Growth Promoting Rhizobacterium Open
Many Rahnella strains have been widely described as plant growth-promoting rhizobacteria with the potential to benefit plant growth and protect plants from pathogens. R. aceris ZF458 is a beneficial plant bacterium isolated from swamp soil…
View article: Double Mutations in Succinate Dehydrogenase Are Involved in SDHI Resistance in Corynespora cassiicola
Double Mutations in Succinate Dehydrogenase Are Involved in SDHI Resistance in Corynespora cassiicola Open
With the further application of succinate dehydrogenase inhibitors (SDHI), the resistance caused by double mutations in target gene is gradually becoming a serious problem, leading to a decrease of control efficacy. It is important to asse…