Shigeru Imamura
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View article: Remarkable Response to Adjunctive Use of Methadone 5 mg Once Daily in a Patient with Refractory Cancer Pain
Remarkable Response to Adjunctive Use of Methadone 5 mg Once Daily in a Patient with Refractory Cancer Pain Open
【緒言】メサドン導入の際は本邦のガイドラインではstop and go法が推奨されているが，一時的な疼痛コントロール不良や重篤な副作用が出現する可能性がある．難治性がん疼痛の患者に対して，先行オピオイドに上乗せして早期に少量のメサドンを導入することで，症状緩和を得た症例を経験した．【症例】70歳男性．直腸吻合部の直腸がん再発による旧肛門部痛に対してタペンタドール，鎮痛補助薬を導入したが疼痛コントロール不良であったため，メサドン5 mg分1を併用した．メサドン開始後は著明な疼…
View article: Progressive brain atrophy and cognitive decline along with multiple episodes of delirium
Progressive brain atrophy and cognitive decline along with multiple episodes of delirium Open
Delirium induces various problems, including prolonged cognitive impairment of which the pathophysiology is unknown.1 We report progressive brain atrophy and cognitive decline along with multiple episodes of delirium within 2 years of admi…