Shih‐Wei Chiang
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View article: Discogenic pain in lumbar vertebra
Discogenic pain in lumbar vertebra Open
Aims Discogenic pain due to intervertebral disc (IVD) degeneration contributes substantially towards low back pain (LBP). This study aims to develop novel and non-invasive diagnostic tools by directly comparing the quantitative results of …
View article: Clinical impact of first-line therapeutic strategies in BRAF V600E-mutant metastatic colorectal cancer: real-world evidence and prognostic insight
Clinical impact of first-line therapeutic strategies in BRAF V600E-mutant metastatic colorectal cancer: real-world evidence and prognostic insight Open
Background BRAF V600E-mutant metastatic colorectal cancer (mCRC) is associated with poor prognosis and limited response to standard therapies. Recent clinical trials have explored the benefit of targeted therapies, but real-world data rema…
View article: Tumor suppression through the interaction between CNTN4 and PTPRG attenuates EGFR signaling in colorectal cancer
Tumor suppression through the interaction between CNTN4 and PTPRG attenuates EGFR signaling in colorectal cancer Open
Chromosome 3 harbors numerous tumor suppressor genes (TSGs) linked to cancer development and progression. We conducted fine deletion mapping on 179 colorectal cancer (CRC) tumors, and herewith revealed a 3.1 Mb minimal deletion region (MDR…
View article: Assessment of Vertebral Bone Marrow Perfusion, Fat/Water Content, and Trabecular Bone Changes Using Multimodal <scp>MRI</scp> and Micro‐<scp>CT</scp> in a Rat Model of Chronic Kidney Disease
Assessment of Vertebral Bone Marrow Perfusion, Fat/Water Content, and Trabecular Bone Changes Using Multimodal <span>MRI</span> and Micro‐<span>CT</span> in a Rat Model of Chronic Kidney Disease Open
Background Disturbances in calcium and phosphorus homeostasis resulting from chronic kidney disease (CKD) may lead to atherosclerotic changes in blood vessels, potentially altering bone marrow perfusion. Our study aimed to investigate vert…
View article: Robotic-Assisted Colon Cancer Surgery: Faster Recovery and Less Pain Compared to Laparoscopy in a Retrospective Propensity-Matched Study
Robotic-Assisted Colon Cancer Surgery: Faster Recovery and Less Pain Compared to Laparoscopy in a Retrospective Propensity-Matched Study Open
Background and Objective: Colorectal cancer (CRC) is the third most common cancer worldwide, with colon cancer accounting for approximately 60% of all CRC cases. Surgery remains the primary and most effective treatment. Robotic-assisted su…
View article: Efficacy of First-line Therapy With Anti-EGFR Versus Anti-VEGF Therapy for WT RAS Metastatic Colorectal Cancer: Real-world Experience from a Single Institute
Efficacy of First-line Therapy With Anti-EGFR Versus Anti-VEGF Therapy for WT RAS Metastatic Colorectal Cancer: Real-world Experience from a Single Institute Open
Background/Aim: Top prospective clinical trials comparing anti-epidermal growth factor receptor (EGFR) therapy and anti-vascular endothelial growth factor (VEGF) therapy plus chemotherapy for wild-type Ras proto-oncogene, GTPase (WT RAS) m…
View article: Rare Complication of Sigmoid Colon Perforation by Migrated Plastic Biliary Stent: Two Case Reports and Literature Review
Rare Complication of Sigmoid Colon Perforation by Migrated Plastic Biliary Stent: Two Case Reports and Literature Review Open
Objective and Introduction:The endoscopic insertion of biliary stents is an alternative solution for biliary tree obstruction in benign or malignant diseases.Despite the availability of a safe and convenient method that has been used for m…
View article: Colo-enteric fistula associated with diffuse large B cell lymphoma that resulted in gastrointestinal bleeding: A case report and literature review
Colo-enteric fistula associated with diffuse large B cell lymphoma that resulted in gastrointestinal bleeding: A case report and literature review Open
View article: Utility of magnetic resonance spectroscopy and diffusion-weighted imaging for detecting changes in the femoral head in divers with hip pain at risk for dysbaric osteonecrosis
Utility of magnetic resonance spectroscopy and diffusion-weighted imaging for detecting changes in the femoral head in divers with hip pain at risk for dysbaric osteonecrosis Open
Dysbaric change in the femoral heads of divers with hip pain can be detected using quantitative MRS, which reveals increases in water content and UI of lipids, and a decrease in TLF.
View article: Hypoperfusion of the infrapatellar fat pad and its relationship to MRI T2* relaxation time changes in a 5/6 nephrectomy model
Hypoperfusion of the infrapatellar fat pad and its relationship to MRI T2* relaxation time changes in a 5/6 nephrectomy model Open
View article: Knee subchondral bone perfusion and its relationship to marrow fat and trabeculation on multi-parametric MRI and micro-CT in experimental CKD
Knee subchondral bone perfusion and its relationship to marrow fat and trabeculation on multi-parametric MRI and micro-CT in experimental CKD Open
View article: Cartilage MRI T2∗ relaxation time and perfusion changes of the knee in a 5/6 nephrectomy rat model of chronic kidney disease
Cartilage MRI T2∗ relaxation time and perfusion changes of the knee in a 5/6 nephrectomy rat model of chronic kidney disease Open
View article: Middle Cerebral Artery Calcification
Middle Cerebral Artery Calcification Open
Calcification of the middle cerebral artery (MCA) is uncommon in the healthy elderly. Whether calcification of the MCA is associated with cerebral ischemic stroke remains undetermined. We intended to investigate the association using Agats…
View article: High Agatston Calcium Score of Intracranial Carotid Artery
High Agatston Calcium Score of Intracranial Carotid Artery Open
The effect of intracranial internal carotid artery (ICA) calcification on cognitive impairment is uncertain. Our objective was to investigate whether intracranial ICA calcification is a significant cognitive predictor for cognitive impairm…
View article: Change in T2* relaxation time of Hoffa fat pad correlates with histologic change in a rat anterior cruciate ligament transection model
Change in T2* relaxation time of Hoffa fat pad correlates with histologic change in a rat anterior cruciate ligament transection model Open
The Hoffa fat pad (infrapatellar fat pad) is a source of post‐traumatic anterior knee pain, and Hoffa disease is a syndrome leading to chronic inflammation of the fat pad. Herein, change in T2 * relaxation time of the fat pad was measured …