Shihe Shao
YOU?
Author Swipe
View article: Circular RNA circDDX17 suppression to gastric cancer progression via the sponging miR-1208/miR-1279/FKBP5 axis encodes a novel circDDX17-63aa protein
Circular RNA circDDX17 suppression to gastric cancer progression via the sponging miR-1208/miR-1279/FKBP5 axis encodes a novel circDDX17-63aa protein Open
Mounting evidence indicates that circular RNAs (circRNAs) are dysregulated in human gastric cancer (GC). The downregulation of circDDX17 is linked to GC progression. However, the role and specific mechanism of circDDX17-mediated GC progres…
View article: Communication molecules (ncRNAs) mediate tumor-associated macrophage polarization and tumor progression
Communication molecules (ncRNAs) mediate tumor-associated macrophage polarization and tumor progression Open
Non-coding RNAs play important roles in tumor cells and macrophages and participate in their communication as messengers. Non-coding RNAs have an impact in tumor cell proliferation, migration, and apoptosis, and they also regulate the diff…
View article: Helicobacter pylori upregulates circPGD and promotes development of gastric cancer
Helicobacter pylori upregulates circPGD and promotes development of gastric cancer Open
Purpose Helicobacter pylori ( H. pylori ) has unique biochemical traits and pathogenic mechanisms, which make it a substantial cause of gastrointestinal cancers. Circular RNAs (circRNAs) have concurrently been identified as an important pa…
View article: Tumor-derived CircRNA_102191 promotes gastric cancer and facilitates M2 macrophage polarization
Tumor-derived CircRNA_102191 promotes gastric cancer and facilitates M2 macrophage polarization Open
CircRNA_102191 promotes the biological function of gastric cancer cells by regulating the miR-493-3p/XPR1 axis and M2 macrophage polarization.
View article: Circular RNA circDDX17 suppression to gastric cancer progression via the sponging miR-1208/miR-1279/FKBP5 axis and encodes a novel circDDX17-63aa protein
Circular RNA circDDX17 suppression to gastric cancer progression via the sponging miR-1208/miR-1279/FKBP5 axis and encodes a novel circDDX17-63aa protein Open
Circular RNAs (circRNAs) have an important role in the development and progression of gastric cancer (GC). Hsa_circ_0063331 (circDDX17), a new circRNA shown to be considerably down-regulated in GC, was chosen for further study. The locatio…
View article: CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p/ZCCHC14 axis
CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p/ZCCHC14 axis Open
Background Helicobacter pylori ( H.pylori, HP ) is one of the main causes of gastric cancer (GC). CircRNAs have been reported to play a crucial role in developing many types of cancer. However, the role of circRNAs in the development and p…
View article: Helicobacter pylori regulates stomach diseases by activating cell pathways and DNA methylation of host cells
Helicobacter pylori regulates stomach diseases by activating cell pathways and DNA methylation of host cells Open
One of the most prevalent malignant tumors of the digestive tract is gastric cancer (GC). Age, high salt intake, Helicobacter pylori ( H. pylori ) infection, and a diet deficient in fruits and vegetables are risk factors for the illness. A…
View article: CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p/ZCCHC14 axis
CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p/ZCCHC14 axis Open
Background Helicobacter pylori ( H.pylori, HP ) is one of the main causes of gastric cancer (GC). CircRNAs have been reported to play a crucial role in developing many types of cancer. However, the role of circRNAs in the development and p…
View article: Additional file 1 of CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p/ZCCHC14 axis
Additional file 1 of CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p/ZCCHC14 axis Open
Additional file 1: Table S1: The sequences of the primers
View article: Low Expression of GIGYF1 Inhibits Metastasis, Proliferation, and Promotes Apoptosis and Autophagy of Gastric Cancer Cells
Low Expression of GIGYF1 Inhibits Metastasis, Proliferation, and Promotes Apoptosis and Autophagy of Gastric Cancer Cells Open
GRB10 interacting GYF protein 1 (GIGYF1) binds to the N-terminal region of Grb10, regulates multiple signaling pathways. However, it is not clear what happens to cell proliferation, metastasis, apoptosis, and autophagy when the expression …
View article: Additional file 2 of CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p/ZCCHC14 axis
Additional file 2 of CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p/ZCCHC14 axis Open
Additional file 2: Table S2: Antibodies used in the article
View article: Tumor-derived CircRNA_102191 promotes gastric cancer and facilitates M2 macrophage polarization
Tumor-derived CircRNA_102191 promotes gastric cancer and facilitates M2 macrophage polarization Open
Background: Gastric cancer is a common malignant tumor of the digestive tract and the fourth leading cause of death from cancer-related diseases. In recent years, many studies have found that circular RNAs play an important role in cancer.…
View article: CircDDX17 enhances coxsackievirus B3 replication through regulating miR-1248/NOTCH receptor 2 axis
CircDDX17 enhances coxsackievirus B3 replication through regulating miR-1248/NOTCH receptor 2 axis Open
Coxsackievirus B3 (CVB3) was one of the most common pathogens to cause viral myocarditis. Circular RNAs as novel non-coding RNAs with a closed loop molecular structure have been confirmed to be involved in virus infectious diseases, but th…
View article: Circular RNA circPGD contributes to gastric cancer progression via the sponging miR-16-5p/ABL2 axis and encodes a novel PGD-219aa protein
Circular RNA circPGD contributes to gastric cancer progression via the sponging miR-16-5p/ABL2 axis and encodes a novel PGD-219aa protein Open
CircRNAs have critical effects on tumor development and progression. However, circPGD effect on gastric cancer (GC) is still elusive. Nuclear and cytoplasmic RNA fractionation, and RNA-FISH assay examined the localization of circPGD in MGC…
View article: 干扰CTPS基因促进川楝素诱导的人胃癌MKN-45细胞凋亡
干扰CTPS基因促进川楝素诱导的人胃癌MKN-45细胞凋亡 Open
OBJECTIVE: To investigate the effect of interference of CTPS gene on toosendanin-induced apoptosis of gastric cancer MKN-45 cells. METHODS: Bioinformatic analysis was used to analyze CTPS gene expression in human gastric cancer tissues and…
View article: Effects of vitamin D treatment on thyroid function and autoimmunity markers in patients with Hashimoto's thyroiditis—A meta‐analysis of randomized controlled trials
Effects of vitamin D treatment on thyroid function and autoimmunity markers in patients with Hashimoto's thyroiditis—A meta‐analysis of randomized controlled trials Open
Our study demonstrated that vitamin D treatment might significantly increase the serum 25(OH)D levels and produce changes in TPO-Ab titres. No significant association was found between serum vitamin D treatment and the levels of TG-Ab, TSH…
View article: Additional file 3 of Deregulation of lncRNA HIST1H2AG-6 and AIM1-3 in peripheral blood mononuclear cells is associated with newly diagnosed type 2 diabetes
Additional file 3 of Deregulation of lncRNA HIST1H2AG-6 and AIM1-3 in peripheral blood mononuclear cells is associated with newly diagnosed type 2 diabetes Open
Additional file 3. Detailed information of enriched GO terms of lnc-HIST1H2AG-6 and lnc-AIM1-3 correlated mRNAs.
View article: microRNA-29a-3p, Up-Regulated in Human Gastric Cells and Tissues with H.Pylori Infection, Promotes the Migration of GES-1 Cells via A20-Mediated EMT Pathway
microRNA-29a-3p, Up-Regulated in Human Gastric Cells and Tissues with H.Pylori Infection, Promotes the Migration of GES-1 Cells via A20-Mediated EMT Pathway Open
Background/Aims: Helicobacter pylori (H. pylori) infection is closely related to human gastric mucosa-associated diseases. Several recent studies on miRNAs have expanded our insights on H.pylori pathogenesis. This study aimed to investigat…
View article: Role of Low-Molecular-Mass Penicillin-Binding Proteins, NagZ and AmpR in AmpC β-lactamase Regulation of Yersinia enterocolitica
Role of Low-Molecular-Mass Penicillin-Binding Proteins, NagZ and AmpR in AmpC β-lactamase Regulation of Yersinia enterocolitica Open
Yersinia enterocolitica encodes a chromosomal AmpC β-lactamase under the regulation of the classical ampR-ampC system. To obtain a further understanding to the role of low-molecular-mass penicillin-binding proteins (LMM PBPs) including PBP…
View article: The role of Notch signaling in gastric carcinoma: molecular pathogenesis and novel therapeutic targets
The role of Notch signaling in gastric carcinoma: molecular pathogenesis and novel therapeutic targets Open
Notch signaling, an evolutionarily conserved signaling cascade system, is involved in promoting the progression of different types of cancers. Within the past decades, the Notch signaling pathway has increasingly been shown to have a prima…
View article: Three Yersinia enterocolitica AmpD Homologs Participate in the Multi-Step Regulation of Chromosomal Cephalosporinase, AmpC
Three Yersinia enterocolitica AmpD Homologs Participate in the Multi-Step Regulation of Chromosomal Cephalosporinase, AmpC Open
In many gram negative bacilli, AmpD plays a key role in both cell well-recycling pathway and β-lactamase regulation, inactivation of the ampD causes the accumulation of 1,6-anhydromuropeptides, and results in the ampC overproduction. In Ye…
View article: An enterovirus from a captive primate in China
An enterovirus from a captive primate in China Open
According to the genetic distance-based criteria, Sev-nj1 belonged to a new type within the species EV-J. This is the first study detecting EV-J from a NHP in China, which will be helpful for the future epidemiology study of EVs in NHPs.