Sun‐Wei Guo
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View article: Letter to the Editor: commentary on “Transanal opening of intersphincteric space (TROPIS) treatment for high complex anal fistula: a systematic review and meta-analysis”
Letter to the Editor: commentary on “Transanal opening of intersphincteric space (TROPIS) treatment for high complex anal fistula: a systematic review and meta-analysis” Open
View article: Availability of region-specific endometriosis care guidance: a global scoping review
Availability of region-specific endometriosis care guidance: a global scoping review Open
View article: An Economic Analysis of Labor Market Structural Changes in the Context of Rapid Artificial Intelligence Development
An Economic Analysis of Labor Market Structural Changes in the Context of Rapid Artificial Intelligence Development Open
With the continuous development and innovation of artificial intelligence (AI), the traditional labor market has been significantly affected. This paper, from an economic perspective, explores how AI influences different types of occupatio…
View article: A radix dipsaci-loaded gelatin methacryloyl nanocomposite hydrogel with slow release and osteogenic effects
A radix dipsaci-loaded gelatin methacryloyl nanocomposite hydrogel with slow release and osteogenic effects Open
Periodontitis induce alveolar bone destruction, which may result in tooth loosening, exfoliation, or oral functional impairment in severe cases. The development of novel therapeutic agents with sustained efficacy and robust mechanical prop…
View article: Reduced vagal tone in women with adenomyosis
Reduced vagal tone in women with adenomyosis Open
Adenomyosis is an estrogen-dependent disease featuring chronic inflammation. This study was undertaken to investigate whether vagal tone is reduced in patients with adenomyosis compared with healthy women. We recruited 75 patients with ade…
View article: Brain-computer interface training for multimodal functional recovery in patients with brain injury: a case series
Brain-computer interface training for multimodal functional recovery in patients with brain injury: a case series Open
Motor imagery-based BCI training may facilitate recovery across motor, language, and cognitive domains in patients with subacute brain injury. Functional gains were supported by neurophysiological and connectomics evidence of cross-network…
View article: Imaging detection of Endometriosis in high-risk young women: The Endometriosis Awareness Promotion Project
Imaging detection of Endometriosis in high-risk young women: The Endometriosis Awareness Promotion Project Open
View article: Bioinformatics-based screening and validation of PANoptosis-related biomarkers in periodontitis
Bioinformatics-based screening and validation of PANoptosis-related biomarkers in periodontitis Open
Background Periodontitis is the most prevalent chronic inflammatory disease affecting the periodontal tissues. PANoptosis, a recently characterized form of programmed cell death, has been implicated in various pathological processes; howev…
View article: How to bridge the gap between evidence-based and clinical management of endometriosis
How to bridge the gap between evidence-based and clinical management of endometriosis Open
View article: Causal relationship between skin microbiota and Hidradenitis suppurativa: a two-sample Mendelian randomization study
Causal relationship between skin microbiota and Hidradenitis suppurativa: a two-sample Mendelian randomization study Open
Our analysis suggests a possible causal relationship between specific skin microbiota and HS. These findings shed light on the potential pathogenesis and therapeutic interventions.
View article: WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Organoids): endometrial organoids as an emerging technology for endometriosis research
WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Organoids): endometrial organoids as an emerging technology for endometriosis research Open
The aetiology of endometriosis remains poorly understood. In vitro model systems provide the opportunity to identify the mechanisms driving disease pathogenesis using human cells. Three-dimensional models, particularly organoid systems, ha…
View article: WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Heterologous): heterologous rodent models
WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Heterologous): heterologous rodent models Open
Endometriosis, defined as the growth of endometrial-like tissues outside the uterus, is a common disease among women. Numerous in vivo rodent models of endometriosis have been developed to explore multiple aspects of this poorly understood…
View article: WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Homologous): homologous rodent models
WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Homologous): homologous rodent models Open
In vivo models of endometriosis enable the discovery and preclinical testing of new therapies. Several rodent models of endometriosis exist, but a lack of harmonization impedes reproducibility and comparability of results among investigato…
View article: WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Pain): methods to assess pain behaviour in rodent models of endometriosis
WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Pain): methods to assess pain behaviour in rodent models of endometriosis Open
Pain is a debilitating symptom of endometriosis, and its mechanisms are often explored using rodent models. However, a lack of harmonization amongst models and behavioural measures, in addition to inconsistent reporting, might limit the ov…
View article: Progressively diminished estrogen signaling concordant with increased fibrosis in ectopic endometrium
Progressively diminished estrogen signaling concordant with increased fibrosis in ectopic endometrium Open
STUDY QUESTION Do all ectopic endometrial lesions (endometriosis and adenomyosis) universally have activated estrogen signaling? SUMMARY ANSWER Estrogen signaling diminishes concordantly with increased fibrosis in ectopic endometrium, with…
View article: Comment on: Toward an optimal contraception dosing strategy
Comment on: Toward an optimal contraception dosing strategy Open
The optimal contraception dosing strategy proposed by Gavina et al. recently is a commendable attempt to model a complex physiological process with potenial to apply to real-life data. However, there is a need to take into account the real…
View article: Dienogest Treatment of Symptomatic Adenomyosis: An In-Depth Meta-Analysis
Dienogest Treatment of Symptomatic Adenomyosis: An In-Depth Meta-Analysis Open
eview question / Objective PICOS Framework: Population: Women with symptomatic adenomyosis, particularly those experiencing dysmenorrhea.Intervention: Treatment with dienogest
View article: Why do oestrogens matter: systematic review and meta-analysis assessing GnRH antagonists, considering add-back therapy, for endometriosis-associated pain
Why do oestrogens matter: systematic review and meta-analysis assessing GnRH antagonists, considering add-back therapy, for endometriosis-associated pain Open
Gonadotrophin-releasing hormone (GnRH) antagonists have been demonstrated to reduce endometriosis-associated pain. Because of the hypo-oestrogenic state they induce, however, higher dosages of GnRH antagonists are not recommended for used …
View article: Adenomyosis and Abnormal Uterine Bleeding: Review of the Evidence
Adenomyosis and Abnormal Uterine Bleeding: Review of the Evidence Open
Background: Thomas Cullen described bleeding abnormalities and dysmenorrhea as the “expected” presentations of adenomyomas. Adenomyosis is included within the FIGO classification of structural causes of abnormal uterine bleeding (AUB). Nev…
View article: Is Neonatal Uterine Bleeding Involved in Early-Onset Endometriosis?
Is Neonatal Uterine Bleeding Involved in Early-Onset Endometriosis? Open
Background: There has been considerable progress in our understanding of endometriosis, but its pathophysiology remains uncertain. Uncovering the underlying mechanism of the rare instances of endometriosis reported in early postmenarcheal …
View article: Reproductive outcomes in women with uterine fibroids: High-intensity focused ultrasound vs. myomectomy
Reproductive outcomes in women with uterine fibroids: High-intensity focused ultrasound vs. myomectomy Open
keywords, and their combinations were used to search for all possible publications: high-intensity focused ultrasound ablation, HIFU, laparoscopy, l a p a ro s c o p e s , l a p a ro s c o p i c , l a p a ro t o m y, laparotomies, abdomina…
View article: The glass ceiling of endometriosis surgeons is research
The glass ceiling of endometriosis surgeons is research Open
View article: Corrigendum to “Neonatal uterine bleeding: Risk factors and its association with endometriosis-related symptoms later in life” [Eur. J. Obstet. Gynecol. Reprod. Biol. 293 (2024) 146–155]
Corrigendum to “Neonatal uterine bleeding: Risk factors and its association with endometriosis-related symptoms later in life” [Eur. J. Obstet. Gynecol. Reprod. Biol. 293 (2024) 146–155] Open
The authors regret “We are very sorry for the careless printing mistake in the proper alignment of case numbers in Table 2, Table 3 of the mentioned article. These case numbers [(n = 25) and (n = 782)] should be read above the line and bel…
View article: Are Adenomyosis and Endometriosis Phenotypes of the Same Disease Process?
Are Adenomyosis and Endometriosis Phenotypes of the Same Disease Process? Open
In recent literature reviews, we concluded that the possibility that endometrial molecular aberrations are the sole or a necessary determinant of endometriosis and the Tissue Injury and Repair (TIAR) theory are yet to be convincingly prove…
View article: Neonatal uterine bleeding: Risk factors and its association with endometriosis-related symptoms later in life
Neonatal uterine bleeding: Risk factors and its association with endometriosis-related symptoms later in life Open
We confirmed the validity of the reported prevalence and risk factors of NUB. NUB indeed occurs with a prevalence of 3-10% during the historical and contemporary period. Longer gestational age and younger maternal age may be considered as …
View article: Events Leading to the Establishment of Pregnancy and Placental Formation: The Need to Fine-Tune the Nomenclature on Pregnancy and Gestation
Events Leading to the Establishment of Pregnancy and Placental Formation: The Need to Fine-Tune the Nomenclature on Pregnancy and Gestation Open
Today, there is strong and diversified evidence that in humans at least 50% of early embryos do not proceed beyond the pre-implantation period. This evidence comes from clinical investigations, demography, epidemiology, embryology, immunol…
View article: HIFU babies: Dose the high-intensity focused ultrasound (HIFU) treatment of adenomyosis improve pregnancy?
HIFU babies: Dose the high-intensity focused ultrasound (HIFU) treatment of adenomyosis improve pregnancy? Open
View article: Shorter Anogenital Distance in Women with Ovarian Endometriomas and Adenomyosis, but Not Uterine Leiomyomas
Shorter Anogenital Distance in Women with Ovarian Endometriomas and Adenomyosis, but Not Uterine Leiomyomas Open
We investigated whether anogenital distance (AGD) is associated with adenomyosis, endometriosis and uterine leiomyomas (UL, also called uterine fibroids). We recruited 81 women with UL, 105 with ovarian endometrioma (OE), 116 with adenomyo…
View article: Is neonatal uterine bleeding responsible for early-onset endometriosis?
Is neonatal uterine bleeding responsible for early-onset endometriosis? Open
View article: An Appraisal of the Tissue Injury and Repair (TIAR) Theory on the Pathogenesis of Endometriosis and Adenomyosis
An Appraisal of the Tissue Injury and Repair (TIAR) Theory on the Pathogenesis of Endometriosis and Adenomyosis Open
As understanding their pathogenesis remains elusive, both endometriosis and adenomyosis are often referred to as “enigmatic diseases”. The uncertainty and heightened interest are reflected in the range of expressed views and opinions. Ther…