Shikui Chen
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View article: Tuning of ILADRC for CFB Boiler Combustion System Based on LF-DCSSA Algorithm
Tuning of ILADRC for CFB Boiler Combustion System Based on LF-DCSSA Algorithm Open
Aiming at the problem that it is difficult to adjust the parameters of the controller in the circulating fluidized bed (CFB) boiler combustion system due to its multivariable and strong coupling, an improved linear active disturbance rejec…
View article: 536 Topology optimization for personalized intracranial aneurysm implant design
536 Topology optimization for personalized intracranial aneurysm implant design Open
Objectives/Goals: To develop a personalized computational framework integrating computational fluid dynamics (CFD) and topology optimization for designing intracranial aneurysm implants. The primary objective is to reduce intra-aneurysmal …
View article: Phase I study, and dosing regimen selection for a pivotal COVID-19 trial of GST-HG171
Phase I study, and dosing regimen selection for a pivotal COVID-19 trial of GST-HG171 Open
This study is aimed to evaluate the safety, tolerability, and pharmacokinetics (PK), as well as to select an appropriate dosing regimen for the pivotal clinical trial of GST-HG171, an orally bioavailable, potent, and selective 3CL protease…
View article: Designing Programmable Ferromagnetic Soft Metastructures for Minimally Invasive Endovascular Therapy
Designing Programmable Ferromagnetic Soft Metastructures for Minimally Invasive Endovascular Therapy Open
Minimally invasive endovascular therapy (MIET) is an innovative technique that utilizes percutaneous access and transcatheter implantation of medical devices to treat vascular diseases. However, conventional devices often face limitations …
View article: Designing Conformal Ferromagnetic Soft Actuators Using Extended Level Set Methods (X-LSM)
Designing Conformal Ferromagnetic Soft Actuators Using Extended Level Set Methods (X-LSM) Open
Ferromagnetic soft materials (FSM) can generate flexible movement and shift morphology in response to an external magnetic field. They have been engineered to design products in a variety of promising applications, such as soft robots, com…
View article: Self-powered Wireless Dual-mode Langasite Sensor for Pressure/Temperature Monitoring of Nuclear Reactors
Self-powered Wireless Dual-mode Langasite Sensor for Pressure/Temperature Monitoring of Nuclear Reactors Open
Safety issues in nuclear power plants are of extreme importance. Numerous sensors are used within nuclear power plants for sensing and monitoring of its critical operation parameters. As currently implemented, during massive losses of powe…
View article: Concurrent optimization of structural topology and infill properties with a CBF-based level set method
Concurrent optimization of structural topology and infill properties with a CBF-based level set method Open
In this paper, a parametric level-set-based topology optimization framework is proposed to concurrently optimize the structural topology at the macroscale and the effective infill properties at the micro/meso scale. The concurrent optimiza…
View article: An Open Source Framework for Integrated Additive Manufacturing and Level-Set-Based Topology Optimization
An Open Source Framework for Integrated Additive Manufacturing and Level-Set-Based Topology Optimization Open
Topology optimization has been considered as a promising tool for conceptual design due to its capability of generating innovative design candidates without depending on the designer's intuition and experience. Various optimization methods…
View article: Numerical Modeling of Metal-Based Additive Manufacturing Using Level Set Methods
Numerical Modeling of Metal-Based Additive Manufacturing Using Level Set Methods Open
The advance in computational science and engineering allows people to simulate the additive manufacturing (AM) process at high fidelity, which has turned out to be a valid way to model, predict, and even design the AM processes. In this pa…