Shiloh R. Lueschow
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View article: State of the art review on machine learning and artificial intelligence in the study of neonatal necrotizing enterocolitis
State of the art review on machine learning and artificial intelligence in the study of neonatal necrotizing enterocolitis Open
Necrotizing Enterocolitis (NEC) is one of the leading causes of gastrointestinal emergency in preterm infants. Although NEC was formally described in the 1960's, there is still difficulty in diagnosis and ultimately treatment for NEC due i…
View article: The fetal response to maternal inflammation is dependent upon maternal IL-6 in a murine model
The fetal response to maternal inflammation is dependent upon maternal IL-6 in a murine model Open
View article: Biomarkers of necrotizing enterocolitis in the era of machine learning and omics
Biomarkers of necrotizing enterocolitis in the era of machine learning and omics Open
View article: Hyaluronic Acid 35 kDa Protects against a Hyperosmotic, Formula Feeding Model of Necrotizing Enterocolitis
Hyaluronic Acid 35 kDa Protects against a Hyperosmotic, Formula Feeding Model of Necrotizing Enterocolitis Open
Necrotizing enterocolitis (NEC), an inflammatory disease of the intestine, is a common gastrointestinal emergency among preterm infants. Intestinal barrier dysfunction, hyperactivation of the premature immune system, and dysbiosis are thou…
View article: Bifidobacterium longum Subspecies infantis Strain EVC001 Decreases Neonatal Murine Necrotizing Enterocolitis
Bifidobacterium longum Subspecies infantis Strain EVC001 Decreases Neonatal Murine Necrotizing Enterocolitis Open
Necrotizing enterocolitis (NEC) is a disease mainly of preterm infants with a 30–50% mortality rate and long-term morbidities for survivors. Treatment strategies are limited and have not improved in decades, prompting research into prevent…
View article: Correction: A critical evaluation of current definitions of necrotizing enterocolitis
Correction: A critical evaluation of current definitions of necrotizing enterocolitis Open
View article: The Paneth Cell: The Curator and Defender of the Immature Small Intestine
The Paneth Cell: The Curator and Defender of the Immature Small Intestine Open
Paneth cells were first described in the late 19th century by Gustav Schwalbe and Josef Paneth as columnar epithelial cells possessing prominent eosinophilic granules in their cytoplasm. Decades later there is continued interest in Paneth …
View article: Feeding Formula Eliminates the Necessity of Bacterial Dysbiosis and Induces Inflammation and Injury in the Paneth Cell Disruption Murine NEC Model in an Osmolality-Dependent Manner
Feeding Formula Eliminates the Necessity of Bacterial Dysbiosis and Induces Inflammation and Injury in the Paneth Cell Disruption Murine NEC Model in an Osmolality-Dependent Manner Open
Necrotizing enterocolitis (NEC) remains a significant cause of morbidity and mortality in preterm infants. Formula feeding is a risk factor for NEC and osmolality, which is increased by the fortification that is required for adequate growt…
View article: Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis
Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis Open
Necrotizing enterocolitis (NEC) remains the leading cause of gastrointestinal morbidity and mortality in premature infants. Human and animal studies suggest a role for Paneth cells in NEC pathogenesis. Paneth cells play critical roles in h…
View article: Western Bats as a Reservoir of Novel Streptomyces Species with Antifungal Activity
Western Bats as a Reservoir of Novel Streptomyces Species with Antifungal Activity Open
At least two-thirds of commercial antibiotics today are derived from Actinobacteria , more specifically from the genus Streptomyces . Antibiotic resistance and new emerging diseases pose great challenges in the field of microbiology. Cave …