Shilpa Narayanan
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View article: Multivariable model of postoperative delirium in cardiac surgery patients: proteomic and demographic contributions
Multivariable model of postoperative delirium in cardiac surgery patients: proteomic and demographic contributions Open
Background Delirium following cardiac surgery is common, morbid, and costly, but may be prevented with risk stratification and targeted intervention. Preoperative protein signatures may identify patients at increased risk for worse postope…
View article: Prediction Models of Shielding Effectiveness of Carbon Fibre Reinforced Cement-Based Composites against Electromagnetic Interference
Prediction Models of Shielding Effectiveness of Carbon Fibre Reinforced Cement-Based Composites against Electromagnetic Interference Open
With the rapid development of communication technology as well as a rapid rise in the usage of electronic devices, a growth of concerns over unintentional electromagnetic interference emitted by these devices has been witnessed. Pioneer re…
View article: Perceived Stress, Resilience, and Wellbeing in Seasoned Isha Yoga Practitioners Compared to Matched Controls During the COVID-19 Pandemic
Perceived Stress, Resilience, and Wellbeing in Seasoned Isha Yoga Practitioners Compared to Matched Controls During the COVID-19 Pandemic Open
Background Yoga practices, including breathing, meditation, and posture protocols (asanas), have been shown to facilitate physical and mental wellbeing. Methods Seasoned yoga practitioners were recruited from the Isha Foundation. Recruitme…
View article: Perioperative Multimodal General Anesthesia Focusing on Specific CNS Targets in Patients Undergoing Cardiac Surgeries: The Pathfinder Feasibility Trial
Perioperative Multimodal General Anesthesia Focusing on Specific CNS Targets in Patients Undergoing Cardiac Surgeries: The Pathfinder Feasibility Trial Open
Multimodal general anesthesia (MMGA) is a strategy that utilizes the well-known neuroanatomy and neurophysiology of nociception and arousal control in designing a rational and clinical practical paradigm to regulate the levels of unconscio…
View article: Neurofilament light: a narrative review on biomarker utility
Neurofilament light: a narrative review on biomarker utility Open
Neurofilament light (NfL) is a scaffolding protein that is located primarily within myelinated axons and that provides increased conduction speed and structural support. In recent years, NfL has been used as a disease biomarker on the basi…
View article: Faculty Opinions recommendation of Effects of methylprednisolone on blood-brain barrier and cerebral inflammation in cardiac surgery-a randomized trial.
Faculty Opinions recommendation of Effects of methylprednisolone on blood-brain barrier and cerebral inflammation in cardiac surgery-a randomized trial. Open
BACKGROUND: Cognitive dysfunction is a frequent complication to open-heart surgery. Cerebral inflammation caused by blood-brain barrier (BBB) dysfunction due to a systemic inflammatory response is considered a possible etiology. The effect…
View article: Scheduled Prophylactic 6-Hourly IV AcetaminopheN to Prevent Postoperative Delirium in Older CaRdiac SurgicAl Patients (PANDORA): protocol for a multicentre randomised controlled trial
Scheduled Prophylactic 6-Hourly IV AcetaminopheN to Prevent Postoperative Delirium in Older CaRdiac SurgicAl Patients (PANDORA): protocol for a multicentre randomised controlled trial Open
Introduction Postoperative delirium is common among older cardiac surgery patients. Often difficult to predict and address prophylactically, delirium complicates the postoperative course by increasing morbidity and mortality as well as pro…