Shiming Zhang
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View article: An ultra-long acting insulin enables glucose-synchronised release
An ultra-long acting insulin enables glucose-synchronised release Open
Delayed and weak glucose-responsive kinetics, coupled with short plasma exposure and complicated formulation, remain major obstacles to the clinical translation of glucose-responsive insulin formulations. Here we report a rapidly absorbabl…
View article: Correction to “A Patch of Detachable Hybrid Microneedle Depot for Localized Delivery of Mesenchymal Stem Cells in Regeneration Therapy”
Correction to “A Patch of Detachable Hybrid Microneedle Depot for Localized Delivery of Mesenchymal Stem Cells in Regeneration Therapy” Open
View article: A fully-integrated flexible in-sensor computing circuit based on gel-gated organic electrochemical transistors
A fully-integrated flexible in-sensor computing circuit based on gel-gated organic electrochemical transistors Open
Organic electrochemical transistors (OECTs) are promising technologies for biosensing and brain-inspired computing due to their low-power signal amplification and neuron-like behavior. However, their manufacturing remains complex, especial…
View article: Improving Long‐Term Glucose Prediction Accuracy with Uncertainty‐Estimated ProbSparse‐Transformer
Improving Long‐Term Glucose Prediction Accuracy with Uncertainty‐Estimated ProbSparse‐Transformer Open
Accurate prediction of blood glucose (BG) with precise data recorded by continuous glucose monitoring (CGM) is essential to improve the safety of closed‐loop insulin delivery systems for diabetic patients. However, predicting BG trends und…
View article: Correction to “A Patch of Detachable Hybrid Microneedle Depot for Localized Delivery of Mesenchymal Stem Cells in Regeneration Therapy”
Correction to “A Patch of Detachable Hybrid Microneedle Depot for Localized Delivery of Mesenchymal Stem Cells in Regeneration Therapy” Open
View article: Electrically programmable organic in-display neuromorphic computing
Electrically programmable organic in-display neuromorphic computing Open
The scale-up of AI models and data makes smart edge devices (e.g. smartphones and AR/VR glasses) face increasing challenges in energy consumption, latency and hardware costs. These challenges are due to their physically separated memory, p…
View article: POS0001 Investigating the Therapeutic Potential of Intestinal Microbiota in Interstitial Lung Disease Associated with Connective Tissue Disease
POS0001 Investigating the Therapeutic Potential of Intestinal Microbiota in Interstitial Lung Disease Associated with Connective Tissue Disease Open
View article: Magnetic Field Driven Ceria Nanosystems for Mitochondria Targeted Therapy of Ischemic Stroke (Adv. Funct. Mater. 24/2025)
Magnetic Field Driven Ceria Nanosystems for Mitochondria Targeted Therapy of Ischemic Stroke (Adv. Funct. Mater. 24/2025) Open
View article: POS0726 ARGININE: A NOVEL THERAPEUTIC STRATEGY FOR PULMONARY FIBROSIS REVEALED BY METABOLOMICS
POS0726 ARGININE: A NOVEL THERAPEUTIC STRATEGY FOR PULMONARY FIBROSIS REVEALED BY METABOLOMICS Open
View article: Smart Organic–Inorganic Copolymer Nanoparticles Distinguish Between Microglia and Cancer Cells for Synergistic Immunotherapy in Glioma
Smart Organic–Inorganic Copolymer Nanoparticles Distinguish Between Microglia and Cancer Cells for Synergistic Immunotherapy in Glioma Open
The stimulator of interferon genes (STING) pathway has emerged as a new immunotherapy strategy with potent local stimulation specificity, showing promising potential to counteract the immunosuppression in glioma. Herein, a tumor microenvir…
View article: Artificial Intelligence‐Enhanced, Closed‐Loop Wearable Systems Toward Next‐Generation Diabetes Management
Artificial Intelligence‐Enhanced, Closed‐Loop Wearable Systems Toward Next‐Generation Diabetes Management Open
Recent advancements in wearable healthcare have led to commercially accessible continuous glucose monitoring systems (CGMs) for diabetes management. However, CGMs only monitor glucose levels and lack therapeutic functions, prompting the de…
View article: Phase Characteristics of Fluids in Offshore Buried Hill Condensate Gas Reservoirs and Their Influence on Formation Permeability
Phase Characteristics of Fluids in Offshore Buried Hill Condensate Gas Reservoirs and Their Influence on Formation Permeability Open
The BZ gas field is the first large gas field in the Bohai Sea of China, with reserves of 100 billion cubic meters. Its formal operation can greatly promote local green and low-carbon development. However, the condensate gas reservoir has …
View article: CO2 high-pressure miscible flooding and storage technology and its application in Shengli Oilfield, China
CO2 high-pressure miscible flooding and storage technology and its application in Shengli Oilfield, China Open
There are various issues for CO2 flooding and storage in Shengli Oilfield, which are characterized by low light hydrocarbon content of oil and high miscible pressure, strong reservoir heterogeneity and low sweep efficiency, gas channeling …
View article: Unravelling the Programmed Inflammation and Tissue Repair by a Multipotential Antimicrobial K21 Silane
Unravelling the Programmed Inflammation and Tissue Repair by a Multipotential Antimicrobial K21 Silane Open
the antimicrobial and reparative efficacy of K21 silane aids in programmed inflammation for enhanced tissue healing and repair.
View article: The Impact of Green Finance on the Profitability of Commercial Banks
The Impact of Green Finance on the Profitability of Commercial Banks Open
As global environmental problems are becoming more and more prominent, green finance, as an important means for commercial banks to cope with climate change and environmental pollution, has received widespread attention from the society. A…
View article: Progress in the study of autophagy-related proteins affecting resistance to chemotherapeutic drugs in leukemia
Progress in the study of autophagy-related proteins affecting resistance to chemotherapeutic drugs in leukemia Open
Leukemia is a life-threatening malignant tumor of the hematopoietic system. Currently, the main treatment modalities are chemotherapy and hematopoietic stem cell transplantation. However, increased drug resistance due to decreased sensitiv…
View article: 118P A multicenter, prospective, non-interventional study to investigate the treatment patterns of neratinib in human epidermal growth factor receptor 2-positive (HER2+) early breast cancer in China: NER-Tree study - An interim analysis on patient characteristics and pretreatment patterns
118P A multicenter, prospective, non-interventional study to investigate the treatment patterns of neratinib in human epidermal growth factor receptor 2-positive (HER2+) early breast cancer in China: NER-Tree study - An interim analysis on patient characteristics and pretreatment patterns Open
Neratinib, an oral irreversible pan-HER tyrosine kinase inhibitor, was approved in 2020 in China based on the ExteNET trial, which is no longer reflective of the current treatment landscape of HER2+ early breast cancer (EBC) in China, with…
View article: Coin-sized, fully integrated, and minimally invasive continuous glucose monitoring system based on organic electrochemical transistors
Coin-sized, fully integrated, and minimally invasive continuous glucose monitoring system based on organic electrochemical transistors Open
Continuous glucose monitoring systems (CGMs) are critical toward closed-loop diabetes management. The field’s progress urges next-generation CGMs with enhanced antinoise ability, reliability, and wearability. Here, we propose a coin-sized,…
View article: High Manganese Content of Lipid NanoMn (LNM) by Microfluidic Technology for Enhancing Anti-Tumor Immunity
High Manganese Content of Lipid NanoMn (LNM) by Microfluidic Technology for Enhancing Anti-Tumor Immunity Open
Immunotherapy is a clinically effective method for treating tumors. Manganese can activate the cGAS-STING signaling pathway and induce an anti-tumor immune response. However, its efficacy is hindered by non-specific distribution and low up…
View article: Continual Learning for Smart City: A Survey
Continual Learning for Smart City: A Survey Open
With the digitization of modern cities, large data volumes and powerful computational resources facilitate the rapid update of intelligent models deployed in smart cities. Continual learning (CL) is a novel machine learning paradigm that c…
View article: A Survey of Route Recommendations: Methods, Applications, and Opportunities
A Survey of Route Recommendations: Methods, Applications, and Opportunities Open
Nowadays, with advanced information technologies deployed citywide, large data volumes and powerful computational resources are intelligentizing modern city development. As an important part of intelligent transportation, route recommendat…
View article: Hierarchical Carbon Nanospheres-Based Electrodes for Low-Temperature Pseudocapacitors
Hierarchical Carbon Nanospheres-Based Electrodes for Low-Temperature Pseudocapacitors Open
View article: Smartphone usage behaviors and their association with De Quervain’s Tenosynovitis (DQT)among college students: a cross-sectional study in Guangxi, China
Smartphone usage behaviors and their association with De Quervain’s Tenosynovitis (DQT)among college students: a cross-sectional study in Guangxi, China Open
View article: Pruning random resistive memory for optimizing analogue AI
Pruning random resistive memory for optimizing analogue AI Open
The rapid advancement of artificial intelligence (AI) has been marked by the large language models exhibiting human-like intelligence. However, these models also present unprecedented challenges to energy consumption and environmental sust…
View article: Dynamic interwell connectivity analysis of multi-layer waterflooding reservoirs based on an improved graph neural network
Dynamic interwell connectivity analysis of multi-layer waterflooding reservoirs based on an improved graph neural network Open
The analysis of interwell connectivity plays an important role in the formulation of oilfield development plans and the description of residual oil distribution. In fact, sandstone reservoirs in China's onshore oilfields generally have the…
View article: Does False Lumen Thrombosis Lead to Better Outcomes in Patients with Aortic Dissection: A Meta-Analysis and Systematic Review
Does False Lumen Thrombosis Lead to Better Outcomes in Patients with Aortic Dissection: A Meta-Analysis and Systematic Review Open
Objectives: For a long time, the association of the false lumen status and the outcomes of patients suffering from aortic dissection has been unclear, so this review article aims to study whether the unobstructed of the false lumen is rela…
View article: Deep learning assisted sparse array ultrasound imaging
Deep learning assisted sparse array ultrasound imaging Open
This study aims to restore grating lobe artifacts and improve the image resolution of sparse array ultrasonography via a deep learning predictive model. A deep learning assisted sparse array was developed using only 64 or 16 channels out o…
View article: Selective Ion Sensing Organic Electrochemical Transistors Suitable for Blood Analysis
Selective Ion Sensing Organic Electrochemical Transistors Suitable for Blood Analysis Open
Organic electrochemical transistors (OECTs) have gained considerable attention due to their ability to simultaneously transduce and amplify ion‐based biological signals into electronic signals in bioelectronics. In this study, functionaliz…
View article: Simulation of the sedimentary characteristics of braided deltas in a Paleogene salty lake, Qaidam Basin, China
Simulation of the sedimentary characteristics of braided deltas in a Paleogene salty lake, Qaidam Basin, China Open
In recent years, oil reservoirs have been discovered in the large-scale delta sedimentary system of a salty lake in the Lower Ganchaigou Formation (E 3 1 ) and the Lower Youshashan Formation (N 2 1 ) in the western part of the Qaidam Basin…
View article: SPDC: A SUPER-POINT AND POINT COMBINING BASED DUAL-SCALE CONTRASTIVE LEARNING NETWORK FOR POINT CLOUD SEMANTIC SEGMENTATION
SPDC: A SUPER-POINT AND POINT COMBINING BASED DUAL-SCALE CONTRASTIVE LEARNING NETWORK FOR POINT CLOUD SEMANTIC SEGMENTATION Open
Semantic segmentation of point clouds is one of the fundamental tasks of point cloud processing and is the basis for other downstream tasks. Deep learning has become the main method to solve point cloud processing. Most existing 3D deep le…