Shinichi Asamura
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View article: Visualization and Optical Manipulation of the Erectile Tissue, Penile Corpus Cavernous
Visualization and Optical Manipulation of the Erectile Tissue, Penile Corpus Cavernous Open
Erectile responses in reproduction have not been analyzed extensively because of the limitation of their visualization analyses of inner penile structure and its dynamic changes. In addition, the complex and rapid changes of erectile respo…
View article: Novel thermoplastic splint for treating congenital auricular deformities with late initiation of treatment
Novel thermoplastic splint for treating congenital auricular deformities with late initiation of treatment Open
Non-surgical treatment for congenital auricular deformities is commonly performed and has relatively favorable outcomes. However, delayed treatment could result in a poor response rate, eventually requiring surgical treatment. Effective no…
View article: Revisiting Our Prior Hypothesis:
Revisiting Our Prior Hypothesis: Open
Objectives: To investigate whether changes in the traction of the lower eyelid retractors (LER) after blepharoptosis surgery affect the depth of the inferior conjunctival fornix and whether this is associated with changes in conjunctivocha…
View article: Flap Failure and Re-exploration in Head and Neck Free Tissue Reconstruction: The Impact of the Venous System Choice
Flap Failure and Re-exploration in Head and Neck Free Tissue Reconstruction: The Impact of the Venous System Choice Open
View article: Extremity Soft-tissue Reconstruction With the Conjoined Latissimus Dorsi–Groin Flap
Extremity Soft-tissue Reconstruction With the Conjoined Latissimus Dorsi–Groin Flap Open
Summary: Extensive soft-tissue defects in the extremities pose a significant challenge in reconstructive surgery. The combined latissimus dorsi (LD) and groin flap technique, a method developed by Harii et al in 1981, has shown promise in …
View article: Topohistological alignments of ocular/penile organs
Topohistological alignments of ocular/penile organs Open
Mammalian visual and genital (hereafter mainly penile) organs have been extensively studied albeit separately. Both organ systems contain sensation devices necessary for visual perception and sexual intercourse. Their terminal structures a…
View article: Dynamics of Immune Cell Infiltration and Fibroblast-Derived IL-33/ST2 Axis Induction in a Mouse Model of Post-Surgical Lymphedema
Dynamics of Immune Cell Infiltration and Fibroblast-Derived IL-33/ST2 Axis Induction in a Mouse Model of Post-Surgical Lymphedema Open
Lymphedema is an intractable disease most commonly associated with lymph node dissection for cancer treatment and can lead to a decreased quality of life. Type 2 T helper (Th2) lymphocytes have been shown to be important in the progression…
View article: A Case Report of Severe Mastitis Leading to Breast Necrosis and Toxic Shock Syndrome during the Puerperium
A Case Report of Severe Mastitis Leading to Breast Necrosis and Toxic Shock Syndrome during the Puerperium Open
View article: Anterolateral Thigh Flap Repair of Ruptured Incisional Hernia with Intractable Ascites after Laparoscopic Liver Resection: A Case Report
Anterolateral Thigh Flap Repair of Ruptured Incisional Hernia with Intractable Ascites after Laparoscopic Liver Resection: A Case Report Open
Intractable ascites is often a problem in cirrhotic patients after liver resection and can become difficult to treat when complicated by abdominal wall incisional hernias. We successfully performed hernia repair using an ALT flap without t…
View article: Ultrasound Irradiation as a Candidate Procedure to Improve the Transdermal Drug Delivery to the Tail Edema of a Mouse Model
Ultrasound Irradiation as a Candidate Procedure to Improve the Transdermal Drug Delivery to the Tail Edema of a Mouse Model Open
Drug therapy for secondary lymphedema has not yet been established. Conventional oral and intravenous administration is difficult to administer in sufficient doses due to adverse events. Therefore, it is necessary to develop a transdermal …
View article: Midforehead Lift for Brow Ptosis Caused by Bilateral Facial Nerve Palsy
Midforehead Lift for Brow Ptosis Caused by Bilateral Facial Nerve Palsy Open
Bilateral facial nerve palsy is an exceedingly rare condition. Sequelae caused by facial paralysis, including facial deformity, visual field disturbance and drooling, can have significant functional, aesthetic and even psychological impact…
View article: Bilateral Ischial Defect after Treatment of Pressure Ulcers in a Patient with Spinal CORD Injury: Case Report
Bilateral Ischial Defect after Treatment of Pressure Ulcers in a Patient with Spinal CORD Injury: Case Report Open
Pressure ulcers are extremely common in individuals with spinal cord injuries, especially ischial pressure ulcers, which have a higher rate of recurrence and are more difficult to treat than those in other regions of the body. We report a …
View article: Novel erectile analyses revealed augmentable penile Lyve‐1, the lymphatic marker, expression
Novel erectile analyses revealed augmentable penile Lyve‐1, the lymphatic marker, expression Open
Purpose The pathophysiology of penis extends to erectile dysfunction (ED) to conditions including sexually transmitted diseases (STDs) and cancer. To date, there has been little research evaluating vascular drainage from the penis. We aime…
View article: Late Hematoma After Feminizing Augmentation Mammoplasty Mimicking Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL).
Late Hematoma After Feminizing Augmentation Mammoplasty Mimicking Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL). Open
We report the case of an Asian transgender patient with late hematoma after feminizing mammoplasty. Bilateral silicone breast implants were inserted into the patient 25 years previously. The right breast gradually became swollen without an…
View article: Developmental and functional roles of androgen and interactive signals for external genitalia and erectile tissues
Developmental and functional roles of androgen and interactive signals for external genitalia and erectile tissues Open
Background Recent progress in molecular and signal analyses revealed essential functions of cellular signals including androgen and related growth factors such as Wnt regulators for external genitalia (ExG) development and its pathogenesis…
View article: Increased infiltration of CD4+ T cell in the complement deficient lymphedema model
Increased infiltration of CD4+ T cell in the complement deficient lymphedema model Open
View article: Transconjunctival Approach for Involutional Entropion: Suggestions and Drawbacks
Transconjunctival Approach for Involutional Entropion: Suggestions and Drawbacks Open
Background: Most current surgical approaches in involutional lower eyelid entropion (ILLE) repair focus upon lower eyelid retractor (LER), mainly through transcutaneous approaches. We have opted to use the transconjunctival approach becaus…
View article: Safety and Pitfalls of Blepharoptosis Surgery in Elderly People
Safety and Pitfalls of Blepharoptosis Surgery in Elderly People Open
Background Elderly patients often have complications of blepharoptosis surgery that can result in the appearance or exacerbation of superficial punctate keratopathy (SPK). However, postoperative changes to SPK status have not been previous…
View article: Wound healing responses of urinary extravasation after urethral injury
Wound healing responses of urinary extravasation after urethral injury Open
The post-surgical fluid leakage from the tubular tissues is a critical symptom after gastrointestinal or urinary tract surgeries. Elucidating the mechanism for such abnormalities is vital in surgical and medical science. The exposure of th…
View article: Emerging structural and pathological analyses on the erectile organ, corpus cavernous containing sinusoids
Emerging structural and pathological analyses on the erectile organ, corpus cavernous containing sinusoids Open
Background The corpus cavernosum (CC) containing sinusoids plays fundamental roles for erection. Analysis of pathological changes in the erectile system is studied by recent experimental systems. Various in vitro models utilizing genital m…
View article: Impaired healing of cutaneous wound in a <i>Trpv1</i> deficient mouse
Impaired healing of cutaneous wound in a <i>Trpv1</i> deficient mouse Open
Transient Receptor Potential (TRP) ion channels mediate the influx of cations into cells responding to chemical or physical stimuli. TRP vanilloid 1 (TRPV1) regulates cutaneous functions. Its function in cutaneous wound healing, however, h…
View article: A visualization system for erectile vascular dynamics
A visualization system for erectile vascular dynamics Open
Erection is an essential process which requires the male penis for copulation. This copulatory process depends on the vascular dynamic regulation of the penis. The corpus cavernosum (CC) in the upper (dorsal) part of the penis plays a majo…
View article: Study to the Effect of Involutional Blepharoptosis Surgery Using Objective and Subjective Parameters
Study to the Effect of Involutional Blepharoptosis Surgery Using Objective and Subjective Parameters Open
Background We investigate the effect of involutional blepharoptosis (IB) surgery based on dry eye symptoms by analysis using objective and subjective measures. Methods We recorded various parameters from patients that underwent levator adv…
View article: Loss of Lower Eyelid Bulge after the Reconstruction of Zygomatic Complex Fractures
Loss of Lower Eyelid Bulge after the Reconstruction of Zygomatic Complex Fractures Open
Background: Surgery for zygomatic complex fractures primarily aims to obtain facial symmetry. We investigated facial symmetry specific to lower eyelid bulges following zygomatic complex fractures approached through the lower eyelid. Method…
View article: Establishment of mouse line showing inducible priapism‐like phenotypes
Establishment of mouse line showing inducible priapism‐like phenotypes Open
Purpose Penile research is expected to reveal new targets for treatment and prevention of the complex mechanisms of its disorder including erectile dysfunction (ED). Thus, analyses of the molecular processes of penile ED and continuous ere…
View article: Pancreatectomy With Artery<i>En-bloc</i>Resection for Pancreatic Neck/Body Cancer: A Single-arm Pilot Study
Pancreatectomy With Artery<i>En-bloc</i>Resection for Pancreatic Neck/Body Cancer: A Single-arm Pilot Study Open
PD-CHAR following neoadjuvant therapy might be feasible for PNBC without severe postoperative complications. Survival benefits in PNBC should be confirmed in further studies.
View article: Development of Surgical and Visualization Procedures to Analyze Vasculatures by Mouse Tail Edema Model
Development of Surgical and Visualization Procedures to Analyze Vasculatures by Mouse Tail Edema Model Open
View article: Lateral Thoracic Artery Can Stabilize Circulation in the Pectoralis Major Myocutaneous Pedicle Flap: Single-center, Prospective, Uncontrolled Case Series
Lateral Thoracic Artery Can Stabilize Circulation in the Pectoralis Major Myocutaneous Pedicle Flap: Single-center, Prospective, Uncontrolled Case Series Open
Background: Head and neck reconstructions using the pectoralis major myocutaneous pedicle flap (PMMF) with thoracoacromial artery alone are prone to hemodynamic instability, possibly leading to infection, prolapse, hematoma, seroma, and pa…
View article: Ethanol treatment of nanoPGA/PCL composite scaffolds enhances human chondrocyte development in the cellular microenvironment of tissue-engineered auricle constructs
Ethanol treatment of nanoPGA/PCL composite scaffolds enhances human chondrocyte development in the cellular microenvironment of tissue-engineered auricle constructs Open
A major obstacle for tissue engineering ear-shaped cartilage is poorly developed tissue comprising cell-scaffold constructs. To address this issue, bioresorbable scaffolds of poly-ε-caprolactone (PCL) and polyglycolic acid nanofibers (nano…
View article: The clinical significance of cytokeratin 20 staining pattern in Merkel cell carcinoma
The clinical significance of cytokeratin 20 staining pattern in Merkel cell carcinoma Open
In the present study, to identify the clinical significance of the cytokeratin (CK) 20 staining pattern in Merkel cell carcinoma (MCC), we retrospectively analyzed the major clinicopathological and immunohistochemical characteristics of 12…