Shizuo Kajiyama
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View article: Dietary Modification with Food Order and Divided Carbohydrate Intake Improves Glycemic Excursions in Healthy Young Women
Dietary Modification with Food Order and Divided Carbohydrate Intake Improves Glycemic Excursions in Healthy Young Women Open
Background/Objectives: Previous studies show that allocating carbohydrates earlier and vegetables/protein later in late-evening meals improves glycemic control in both healthy individuals and those with type 2 diabetes. However, evidence r…
View article: Adding Lemon and n-3 PUFA-Rich Oil to Tomato Juice Preload to a Carbohydrate Meal Ameliorates Early Glycemic and Insulin Responses in Young Healthy Women: A Randomized Crossover Trial
Adding Lemon and n-3 PUFA-Rich Oil to Tomato Juice Preload to a Carbohydrate Meal Ameliorates Early Glycemic and Insulin Responses in Young Healthy Women: A Randomized Crossover Trial Open
The aim was to evaluate the acute effect of drinking tomato juice preloaded with lemon and perilla oil 10 min before consuming carbohydrate on postprandial blood glucose, insulin, and lipids concentrations in young healthy women. In this r…
View article: Consumption in a Full-Course Meal Manner Is Associated with a Reduced Mean Amplitude of Glycemic Excursions in Young Healthy Women: A Randomized Controlled Crossover Trial
Consumption in a Full-Course Meal Manner Is Associated with a Reduced Mean Amplitude of Glycemic Excursions in Young Healthy Women: A Randomized Controlled Crossover Trial Open
This study aimed to evaluate the acute effects of consuming in a full-course meal manner over one hour, with intervals between courses, on glycemic and insulin parameters in young healthy women, with a randomized controlled crossover study…
View article: Home blood pressure-lowering effect of a non-steroidal mineralocorticoid receptor blocker, esaxerenone, versus trichlormethiazide for uncontrolled hypertension: the EXCITE-HT randomized controlled study
Home blood pressure-lowering effect of a non-steroidal mineralocorticoid receptor blocker, esaxerenone, versus trichlormethiazide for uncontrolled hypertension: the EXCITE-HT randomized controlled study Open
The EXCITE-HT study aimed to evaluate the efficacy and safety of esaxerenone versus thiazide diuretics (trichlormethiazide) as second-line treatment for Japanese patients with uncontrolled essential hypertension. This was a 12-week, multic…
View article: Eating Vegetables First Regardless of Eating Speed Has a Significant Reducing Effect on Postprandial Blood Glucose and Insulin in Young Healthy Women: Randomized Controlled Cross-Over Study
Eating Vegetables First Regardless of Eating Speed Has a Significant Reducing Effect on Postprandial Blood Glucose and Insulin in Young Healthy Women: Randomized Controlled Cross-Over Study Open
People with fast eating habits have been reported to have an increased risk of diabetes and obesity. To explore whether the speed of eating a test meal (tomato, broccoli, fried fish, and boiled white rice) influences postprandial blood glu…
View article: The Effects of Metformin on the Gut Microbiota of Patients with Type 2 Diabetes: A Two-Center, Quasi-Experimental Study
The Effects of Metformin on the Gut Microbiota of Patients with Type 2 Diabetes: A Two-Center, Quasi-Experimental Study Open
Metformin is reported to affect human gut microbiota; however, the nature of this association in Japanese patients with type 2 diabetes mellitus (T2DM) is unknown. We enrolled 31 patients with T2DM who took metformin for the first time in …
View article: Eating Fast Has a Significant Impact on Glycemic Excursion in Healthy Women: Randomized Controlled Cross-Over Trial
Eating Fast Has a Significant Impact on Glycemic Excursion in Healthy Women: Randomized Controlled Cross-Over Trial Open
Epidemiological studies have shown that self-reported fast eating increases the risk of diabetes and obesity. Our aim was to evaluate the acute effect of fast eating on glycemic parameters through conducting a randomized controlled cross-o…
View article: Food Order and Food Timing Effect Glycemic Excursions: Consuming Dinner Dividedly May Have an Advantage for Improvement of Metabolic Control and May Prevent Future Type 2 Diabetes and Metabolic Syndrome
Food Order and Food Timing Effect Glycemic Excursions: Consuming Dinner Dividedly May Have an Advantage for Improvement of Metabolic Control and May Prevent Future Type 2 Diabetes and Metabolic Syndrome Open
本稿では，何をどれだけ食べるか，すなわち栄養のバランスに留意しながら適切な栄養量を摂取する従来の食事療法に加え，さらに食事をどのように食べるのか，「食べる順番」の違いにより，食後血糖値やインスリンなどホルモンの分泌がどのように変化するかを概説する．次に，朝食の欠食や夜間の食事摂取は，体重増加につながることが知られているが，遅い時刻の夕食摂取と血糖値の関係についてはまだ明らかにされていない．食事をいつ食べるのか，食べる時間の違いが血糖値に与える影響について概説する．食後高血糖…
View article: Divided consumption of late-night-dinner improves glycemic excursions in patients with type 2 diabetes: A randomized cross-over clinical trial
Divided consumption of late-night-dinner improves glycemic excursions in patients with type 2 diabetes: A randomized cross-over clinical trial Open
Our findings demonstrated that consuming late-night-dinner led to postprandial hyperglycemia, and this postprandial hyperglycemia can be ameliorated by consuming a divided dinner.
View article: Comment on Shukla et al. Food Order Has a Significant Impact on Postprandial Glucose and Insulin Levels. Diabetes Care 2015;38:e98–e99
Comment on Shukla et al. Food Order Has a Significant Impact on Postprandial Glucose and Insulin Levels. Diabetes Care 2015;38:e98–e99 Open
We appreciated the article by Shukla et al. (1) showing that food order had a significant impact on postprandial glucose and insulin levels in obese patients with type 2 diabetes in U.S. However, we have already reported not only the same …