Shipra Roy
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View article: P-1242. Missing big in our little patients: Vancomycin trough concentrations do not predict IDSA guideline targeted AUCs
P-1242. Missing big in our little patients: Vancomycin trough concentrations do not predict IDSA guideline targeted AUCs Open
Background Therapeutic drug monitoring is the guideline-recommended, standard of care for vancomycin because of the known efficacy and safety exposure window [i.e. area under the concentration curve (AUC) of 400-600 mg*24hours/L]. Yet, sur…
View article: Big Data Bayesian Truths: No Vancomycin Trough Concentration Target Is Sufficiently Precise for Safety or Efficacy
Big Data Bayesian Truths: No Vancomycin Trough Concentration Target Is Sufficiently Precise for Safety or Efficacy Open
Introduction Therapeutic drug monitoring is standard of care for vancomycin because of the known efficacy and safety exposure window (ie, area under the concentration-time curve [AUC] of 400–600 mg × 24 hours/L). Despite guideline recommen…
View article: Comparison of midpoint transverse process to pleura (MTP) block and erector spinae plane block (ESP) for postoperative analgesia in modified radical mastectomy patients: A double-blinded, randomized control trial
Comparison of midpoint transverse process to pleura (MTP) block and erector spinae plane block (ESP) for postoperative analgesia in modified radical mastectomy patients: A double-blinded, randomized control trial Open
Background and Aims: Modified radical mastectomy (MRM) is associated with moderate severity of postoperative pain. Besides intravenous (IV) analgesics, various nerve blocks are being described for pain relief of MRM patients. We compared e…
View article: Comparison of Diagnostic Accuracy of Presepsin and Procalcitonin for Sepsis in Critically Ill Patients: A Prospective Observational Study
Comparison of Diagnostic Accuracy of Presepsin and Procalcitonin for Sepsis in Critically Ill Patients: A Prospective Observational Study Open
Roy S, Kothari N, Sharma A, Goyal S, Sankanagoudar S, Bhatia PK, et al. Comparison of Diagnostic Accuracy of Presepsin and Procalcitonin for Sepsis in Critically Ill Patients: A Prospective Observational Study. Indian J Crit Care Med 2023;…
View article: Comparison of Binaural Tone Music vs Patient Choice Music vs Midazolam on Perioperative Anxiety in Patients Posted for Surgery Under Spinal Anaesthesia: a Randomized Control Trial
Comparison of Binaural Tone Music vs Patient Choice Music vs Midazolam on Perioperative Anxiety in Patients Posted for Surgery Under Spinal Anaesthesia: a Randomized Control Trial Open
Background Perioperative anxiety affects patients' hemodynamics by increasing stress levels, leading to delayed recovery. In this study, we compared the anxiety-reducing effect of music (patient choice and binaural tone music) with midazol…
View article: Ultrasound-guided dilation of central venous catheter track to prevent dilator-related injury
Ultrasound-guided dilation of central venous catheter track to prevent dilator-related injury Open
Sir, While placing a central venous catheter (CVC), complications such as inadvertent arterial puncture, hematoma formation, massive hemothorax, or pneumothorax can occur. Even with the use of ultrasound (US), complications can happen when…
View article: Hypocalcaemia-induced acute exacerbation of bronchial asthma: An unusual cause of a common disorder
Hypocalcaemia-induced acute exacerbation of bronchial asthma: An unusual cause of a common disorder Open
Sir, An acute exacerbation of bronchial asthma may present abruptly, even without prodromal symptoms. Severe hypocalcaemia can precipitate bronchospasm which can mimic asthma exacerbation.[1] A combination of these conditions poses a diagn…
View article: The Two-Component Signaling System VraSR <sub>ss</sub> Is Critical for Multidrug Resistance and Full Virulence in Streptococcus suis Serotype 2
The Two-Component Signaling System VraSR <sub>ss</sub> Is Critical for Multidrug Resistance and Full Virulence in Streptococcus suis Serotype 2 Open
Streptococcus suis has received increasing attention for its involvement in severe human infections worldwide as well as in multidrug resistance. Two-component signaling systems (TCSSs) play important roles in bacterial adaptation to vario…