Chao Wang
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View article: Integrated photonic platform with high-speed entanglement generation and witnessing
Integrated photonic platform with high-speed entanglement generation and witnessing Open
High-speed generation and efficient entanglement detection on a photonic chip are essential for quantum information applications but hard to achieve due to common photonic chips’ material properties and limited component performance. In th…
View article: Single-nucleus RNA sequencing reveals HBV-driven metabolic reprogramming and TIMP1-mediated fibrosis in human-liver-chimeric mice
Single-nucleus RNA sequencing reveals HBV-driven metabolic reprogramming and TIMP1-mediated fibrosis in human-liver-chimeric mice Open
Introduction Hepatitis B virus (HBV) infection remains a leading cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma worldwide. Despite advances in antiviral therapies, the mechanisms underlying HBV-induced metabolic re…
View article: Clinical analysis of dry eye after refractive surgery in army recruits in 2024
Clinical analysis of dry eye after refractive surgery in army recruits in 2024 Open
View article: A Comprehensive Review of Fortification, Bioavailability, and Health Benefits of Folate
A Comprehensive Review of Fortification, Bioavailability, and Health Benefits of Folate Open
Folate is an essential vitamin involved in one-carbon metabolism. It can be acquired from many food sources or in synthetic form. A wide range of processing methods have been studied to improve the bioaccessibility and bioavailability of f…
View article: Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen (Adv. Sci. 32/2025)
Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen (Adv. Sci. 32/2025) Open
View article: Correction: Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy
Correction: Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy Open
[This corrects the article DOI: 10.3389/fimmu.2025.1561560.].
View article: BlueLM-2.5-3B Technical Report
BlueLM-2.5-3B Technical Report Open
We present BlueLM-2.5-3B, a compact and unified dense Multimodal Large Language Model (MLLM) designed for efficient edge-device deployment, offering strong general-purpose and reasoning capabilities. To the best of our knowledge, this is t…
View article: The Morphology and Ultrastructure of Mesenteric Lymphatic Vessels in Mice
The Morphology and Ultrastructure of Mesenteric Lymphatic Vessels in Mice Open
Objective: To investigate the morphological ultrastructure of mesenteric lymphatic vessels in mice. Methods: Fourteen male Kunming mice (6–8 weeks old, 18–22 g) were subjected to a 24-hour fasting period with unrestricted access to water, …
View article: A chaperonin <scp>BnaC01</scp>.<scp>CCT8</scp> contributes to silique length and seed weight by affecting auxin and jasmonic acid signalling in <i>Brassica napus</i>
A chaperonin <span>BnaC01</span>.<span>CCT8</span> contributes to silique length and seed weight by affecting auxin and jasmonic acid signalling in <i>Brassica napus</i> Open
Summary Seed weight (SW), which is directly influenced by silique length (SL), is a critical agronomic trait significantly affecting both the quality and yield of rapeseed. In this study, a shorter silique length ( ssl ) mutant was generat…
View article: Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen
Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen Open
The pericellular matrix (PCM) is the immediate microniche surrounding cells in various tissues, regulating matrix turnover, cell‐matrix interactions, and disease. This study elucidates the structure‐mechanical properties and mechanobiology…
View article: Endothelial selective adhesion molecule and interleukin-16 play an intermediary role in psoriasis complicated with acute myocardial infarction: A Mendelian randomization study
Endothelial selective adhesion molecule and interleukin-16 play an intermediary role in psoriasis complicated with acute myocardial infarction: A Mendelian randomization study Open
Psoriasis is a prevalent inflammatory skin disorder, often associated with an increased risk of atherosclerosis. Despite growing evidence suggesting a potential link between psoriasis and acute myocardial infarction (AMI), the causal relat…
View article: Clinical analysis of dry eye after refractive surgery in army recruits in 2024
Clinical analysis of dry eye after refractive surgery in army recruits in 2024 Open
Background Dry eye is among the most prevalent complications following refractive surgery, significantly impacting the training and daily lives of recruits. While recent years we have witnessed some advancements in understanding the occurr…
View article: Mediating effect of TyG index on the association between glucose-lipid metabolism-related dietary pattern and T2DM: a propensity score-matched analysis
Mediating effect of TyG index on the association between glucose-lipid metabolism-related dietary pattern and T2DM: a propensity score-matched analysis Open
View article: Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy
Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy Open
Thymidine phosphorylase (TYMP), a protein found in both prokaryotic and eukaryotic cells, is encoded by a gene located in the q13 region of chromosome 22. With a relative molecular mass of 55,000, TYMP exists as a homodimer. Recent researc…
View article: Comparison of the surgical efficacy of total hip replacement versus hemiarthroplasty in the treatment of femoral neck fractures in elderly patients with sarcopenia
Comparison of the surgical efficacy of total hip replacement versus hemiarthroplasty in the treatment of femoral neck fractures in elderly patients with sarcopenia Open
Background Total hip arthroplasty (THA) and hemiarthroplasty (HA) are common surgical procedures for femoral neck fracture (FNF) in elderly patients; however, optimal treatment options remain controversial. Currently, limited research has …
View article: A Feature Engineering Method for Whole-Genome DNA Sequence with Nucleotide Resolution
A Feature Engineering Method for Whole-Genome DNA Sequence with Nucleotide Resolution Open
Feature engineering for whole-genome DNA sequences plays a critical role in predicting plant phenotypic traits. However, due to limitations in the models’ analytical capabilities and computational resources, the existing methods are predom…
View article: DPImpute: A Genotype Imputation Framework for Ultra‐Low Coverage Whole‐Genome Sequencing and its Application in Genomic Selection
DPImpute: A Genotype Imputation Framework for Ultra‐Low Coverage Whole‐Genome Sequencing and its Application in Genomic Selection Open
Whole‐genome sequencing is pivotal for elucidating the complex relationships between genotype and phenotype. However, its widespread application is hindered by the high sequencing depth and large sample sizes required, especially for genom…
View article: Unmasking cerebral infarction: hemianopia and heavy menstrual bleeding in a patient with adenomyosis and vascular abnormalities
Unmasking cerebral infarction: hemianopia and heavy menstrual bleeding in a patient with adenomyosis and vascular abnormalities Open
This case highlights the need for a multidisciplinary approach in young patients with atypical risk factors. The findings underscore the importance of considering gynecological, vascular, and coagulation abnormalities in the evaluation of …
View article: Identification of a tertiary lymphoid structure (TLS)-related signature for ovarian cancer prognosis suggests a potential role of STAT5A in TLS maturation
Identification of a tertiary lymphoid structure (TLS)-related signature for ovarian cancer prognosis suggests a potential role of STAT5A in TLS maturation Open
View article: Quantitative long-term health impact evaluation of phenol residual from river pollution incident emitting: A pilot study of novel conceptual method
Quantitative long-term health impact evaluation of phenol residual from river pollution incident emitting: A pilot study of novel conceptual method Open
View article: High Pollution and Health Risk of Antibiotic Resistance Genes in Rural Domestic Sewage in Southeastern China: A Study Combining National-Scale Distribution and Machine Learning
High Pollution and Health Risk of Antibiotic Resistance Genes in Rural Domestic Sewage in Southeastern China: A Study Combining National-Scale Distribution and Machine Learning Open
View article: Identification of Sars2, Pkn1, and Il11ra as Causally-Associated Genes for Patients with Gastric Cancer Via Immune Cell Activity: A Multi-Omics Mendelian Randomization Study Integrating Gwas, Eqtl, and Pqtl Data
Identification of Sars2, Pkn1, and Il11ra as Causally-Associated Genes for Patients with Gastric Cancer Via Immune Cell Activity: A Multi-Omics Mendelian Randomization Study Integrating Gwas, Eqtl, and Pqtl Data Open
View article: Interaction of high pressure-stressed soy protein isolate and 5-methyltetrahydrofolate and its impact on the stability of 5-methyltetrahydrofolate
Interaction of high pressure-stressed soy protein isolate and 5-methyltetrahydrofolate and its impact on the stability of 5-methyltetrahydrofolate Open
View article: Dual-Channel Dynamic Gated Spatio-Temporal Graph for Traffic Flow Forecasting
Dual-Channel Dynamic Gated Spatio-Temporal Graph for Traffic Flow Forecasting Open
Traffic flow forecasting is a critical and essential technology in the field of Intelligent Transportation Systems (ITS), as it plays a pivotal role in optimizing traffic management, improving road safety, and enhancing the overall efficie…
View article: Development and validation of a nomogram model for predicting lymph node metastasis in early non-small-cell lung cancer
Development and validation of a nomogram model for predicting lymph node metastasis in early non-small-cell lung cancer Open
This study aimed to identify risk factors associated with lymph node metastasis (LNM) in early non-small-cell lung cancer (eNSCLC) patients and to develop a nomogram model for individualized LNM risk assessment. A retrospective analysis wa…
View article: A Neutrophil Extracellular Traps–Related Signature Predicts Clinical Outcomes and Identifies Immune Landscape in Ovarian Cancer
A Neutrophil Extracellular Traps–Related Signature Predicts Clinical Outcomes and Identifies Immune Landscape in Ovarian Cancer Open
Ovarian cancer (OvCa) is the most lethal gynaecology malignancies worldwide. Neutrophil extracellular traps (NETs), net‐like protein structures produced by activated neutrophils and DNA‐histone complexes, have a central role in tumours, th…
View article: Self-testing quantum randomness expansion on an integrated photonic chip
Self-testing quantum randomness expansion on an integrated photonic chip Open
The power of quantum random number generation is more than just the ability to create truly random numbers$\unicode{x2013}$it can also enable self-testing, which allows the user to verify the implementation integrity of certain critical qu…
View article: Protective Effect of Modified Suanmei-Tang on Metabolic-Associated Fatty Liver Disease: An Integrated Strategy of Network Pharmacology, Metabolomics, and Transcriptomics
Protective Effect of Modified Suanmei-Tang on Metabolic-Associated Fatty Liver Disease: An Integrated Strategy of Network Pharmacology, Metabolomics, and Transcriptomics Open
MST could effectively improve lipid metabolism disorders and liver lipid deposition in MAFLD mice, and its mechanism might be related to regulating the PI3K/AKT/mTOR pathway to improve autophagy.
View article: Corrigendum to “Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment” [Neoplasia, Volume 22, Issue 2 (2020) 111–119]
Corrigendum to “Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment” [Neoplasia, Volume 22, Issue 2 (2020) 111–119] Open
View article: GISExplainer: On Explainability of Graph Neural Networks via Game-theoretic Interaction Subgraphs
GISExplainer: On Explainability of Graph Neural Networks via Game-theoretic Interaction Subgraphs Open
Explainability is crucial for the application of black-box Graph Neural Networks (GNNs) in critical fields such as healthcare, finance, cybersecurity, and more. Various feature attribution methods, especially the perturbation-based methods…