Salma Patel
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View article: Increased c-Fos Expression of Lateral Habenula during Social Transmission of Negative Valence in Prairie Voles
Increased c-Fos Expression of Lateral Habenula during Social Transmission of Negative Valence in Prairie Voles Open
Background Social learning is the process of acquiring social skills, new information, or associating negative or positive valence to a context through the observation of others and through direct social interaction with others. Neurodevel…
View article: 0260 Mapping the Brain Around the Clock: Spontaneous Neural Activity Is Influenced by Time Awake and Time of Day
0260 Mapping the Brain Around the Clock: Spontaneous Neural Activity Is Influenced by Time Awake and Time of Day Open
Introduction The timing and depth of sleep and wakefulness are influenced by a homeostatic process that reflects accumulating sleep pressure over time (Process S) and a circadian process (Process C) that produces an oscillating diurnal rhy…
View article: 1444 High-Altitude Periodic Breathing: Diagnostic and Management Challenges
1444 High-Altitude Periodic Breathing: Diagnostic and Management Challenges Open
Introduction High-altitude periodic breathing (HAPB) is characterized by alternating cycles of central apnea and hyperpnea driven by hypoxia and ventilatory instability at high altitudes. These fluctuations can fragment sleep, causing freq…
View article: 1516 Diagnostic and Therapeutic Challenges in Obstructive Sleep Apnea with Prominent Central Events: Revisiting the 50% Criterion
1516 Diagnostic and Therapeutic Challenges in Obstructive Sleep Apnea with Prominent Central Events: Revisiting the 50% Criterion Open
Introduction Obstructive sleep apnea (OSA) is a prevalent sleep-related breathing disorder characterized by repeated upper airway collapse during sleep, leading to fragmented sleep, daytime fatigue, and increased cardiovascular risks. OSA …
View article: 0873 The Effects of Jet Lag and Circadian Acclimation of Performance, Sleep, and 6-sulfatoxymelatonin on Psychomotor Vigilance Reaction Times
0873 The Effects of Jet Lag and Circadian Acclimation of Performance, Sleep, and 6-sulfatoxymelatonin on Psychomotor Vigilance Reaction Times Open
Introduction Jet lag is a disruption of circadian rhythms caused by a mismatch between the body’s internal clock and the local time, often resulting from travel across time zones or significant shifts in sleep patterns due to work or socia…
View article: 0514 Pre-Sleep Salience Network Connectivity Predicts Subsequent REM Duration and Sleep Efficiency
0514 Pre-Sleep Salience Network Connectivity Predicts Subsequent REM Duration and Sleep Efficiency Open
Introduction The hyperarousal theory of insomnia proposes that excessive physiological and psychological arousal contributes to the etiology of insomnia. Previous neuroimaging studies have corroborated this by finding that large-scale neur…
View article: 0281 Trait Extraversion Predicts Psychomotor Vigilance Performance and Changes in Functional Connectivity During Sleep Deprivation
0281 Trait Extraversion Predicts Psychomotor Vigilance Performance and Changes in Functional Connectivity During Sleep Deprivation Open
Introduction Individual differences in resilience to sleep deprivation may be influenced by personality type. Previous research indicates a relationship between the NEO Personality Inventory’s (NEO-PI) Extraversion measure and decline in P…
View article: 0872 Age-Related Differences in Heart Rate and Variability During Simulated Jet Lag: Effects of Bright Light, Exercise, and Melatonin
0872 Age-Related Differences in Heart Rate and Variability During Simulated Jet Lag: Effects of Bright Light, Exercise, and Melatonin Open
Introduction Jet lag is a circadian rhythm disorder caused by misalignment of the body’s internal clock with local time after traveling through multiple time zones. The effects of jet lag may intensify with age. This study evaluates age-re…
View article: 0876 Age-Dependent Effects of Jet Lag on Ventricular Depolarization: Impact of Bright Light, Melatonin, and Exercise
0876 Age-Dependent Effects of Jet Lag on Ventricular Depolarization: Impact of Bright Light, Melatonin, and Exercise Open
Introduction Jet lag is a circadian rhythm disorder that disrupts the body’s biological clock, with its effects potentially varying by age. This study investigates the influence of age on ventricular depolarization, measured by corrected Q…
View article: 0799 The Efficacy of Oral Appliance Therapy in Managing Positional Obstructive Sleep Apnea
0799 The Efficacy of Oral Appliance Therapy in Managing Positional Obstructive Sleep Apnea Open
Introduction Positional obstructive sleep apnea (POSA) is characterized by a significant increase in airway obstruction and breathing disturbances when a patient sleeps in the supine position compared to sleeping on their side. While mandi…
View article: 0217 Neuroticism Traits Predict Resilience to Executive Function Decline During Sleep Deprivation
0217 Neuroticism Traits Predict Resilience to Executive Function Decline During Sleep Deprivation Open
Introduction Sleep deprivation (SD) impairs a range of cognitive abilities. There are also consistent inter-individual differences in resilience to these effects. Prior work suggests that personality traits such neuroticism, trait-anger, a…
View article: 1503 Floppy Eyelid Syndrome: An Overlooked Indicator for Diagnosing Obstructive Sleep Apnea
1503 Floppy Eyelid Syndrome: An Overlooked Indicator for Diagnosing Obstructive Sleep Apnea Open
Introduction Obstructive sleep apnea (OSA) is characterized by recurrent episodes of disrupted breathing during sleep, caused by upper airway obstruction. It affects a substantial portion of the U.S. adult population, with millions estimat…
View article: 0559 Continuous Theta Burst Stimulation and Pre-Sleep Worry
0559 Continuous Theta Burst Stimulation and Pre-Sleep Worry Open
Introduction Continuous theta burst stimulation (cTBS), a type of repetitive transcranial magnetic stimulation (rTMS), has been shown to reduce the severity of insomnia and anxiety in participants with insomnia. This study examined whether…
View article: 0639 Demographic, Clinical, and Treatment Characteristics in a Large Cohort of Patients Evaluated for Sleep Apnea
0639 Demographic, Clinical, and Treatment Characteristics in a Large Cohort of Patients Evaluated for Sleep Apnea Open
Introduction Sleep apnea is a sleep-related breathing disorder characterized by repeated interruptions in breathing, encompassing two main types: obstructive sleep apnea (OSA), caused by airway obstruction, and central sleep apnea (CSA), r…
View article: Polysomnographically mediated cognitive improvements in individuals with insomnia symptoms following continuous theta-burst stimulation of the default mode network
Polysomnographically mediated cognitive improvements in individuals with insomnia symptoms following continuous theta-burst stimulation of the default mode network Open
Introduction Insomnia is associated with mild cognitive impairment, although the mechanisms of this impairment are not well-understood. Timing of slow-wave and rapid eye movement sleep may help explain cognitive impairments common in insom…
View article: 0435 Continuous Theta-burst Stimulation Lowers the Impact of Anxiety on Sleep Duration in Individuals with Insomnia
0435 Continuous Theta-burst Stimulation Lowers the Impact of Anxiety on Sleep Duration in Individuals with Insomnia Open
Introduction Repetitive Transcranial Magnetic Stimulation (rTMS) is a procedure by which a magnetic coil is used to stimulate specific regions of the brain to bring about alterations in function. Continuous theta-burst stimulation (cTBS) i…
View article: 0675 Effects of Circadian Acclimation of Performance, Sleep, 6-sulfatoxymelatonin on Heart Rate & Heart Rate Variability
0675 Effects of Circadian Acclimation of Performance, Sleep, 6-sulfatoxymelatonin on Heart Rate & Heart Rate Variability Open
Introduction Jet lag is associated with transmeridian travel across at least two time zones, associated with sleep disturbance as well as daytime dysfunction. The presence of jet lag has been hypothesized to be associated with adverse card…
View article: 0433 Suppression of the Default Mode Network Affects the Arousal and Reduces Time in Non-Restorative Sleep
0433 Suppression of the Default Mode Network Affects the Arousal and Reduces Time in Non-Restorative Sleep Open
Introduction We recently demonstrated that continuous theta burst stimulation (cTBS), a form of suppressive transcranial magnetic stimulation (TMS), was effective at improving total sleep time, sleep efficiency and arousal index scores in …
View article: Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep in Individuals With Insomnia Symptoms: Protocol for a Double-Blind Randomized Controlled Trial
Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep in Individuals With Insomnia Symptoms: Protocol for a Double-Blind Randomized Controlled Trial Open
Background Cortical hyperarousal and ruminative thinking are common aspects of insomnia that have been linked with greater connectivity in the default mode network (DMN). Therefore, disrupting network activity within the DMN may reduce cor…
View article: Genetic QT Score and Sleep Apnea as Predictors of Sudden Cardiac Death in the UK Biobank
Genetic QT Score and Sleep Apnea as Predictors of Sudden Cardiac Death in the UK Biobank Open
Introduction The goal of this study was to evaluate the association between a polygenic risk score (PRS) for QT prolongation (QTc-PRS), QTc intervals and mortality in patients enrolled in the UK Biobank with and without sleep apnea. Method…
View article: Case report: A case of complete resolution of obstructive and central sleep apnea with Cheyne Stokes breathing in a patient with heart failure 60 days post-left ventricular assist device implantation
Case report: A case of complete resolution of obstructive and central sleep apnea with Cheyne Stokes breathing in a patient with heart failure 60 days post-left ventricular assist device implantation Open
Sleep-disordered breathing (obstructive and central sleep apnea) are common in patients with heart failure with reduced ejection fraction. Herein, we report a 69-year-old patient with a history of severe heart failure and refractory ventri…
View article: Functional connectivity of the default mode network predicts subsequent polysomnographically measured sleep in people with symptoms of insomnia
Functional connectivity of the default mode network predicts subsequent polysomnographically measured sleep in people with symptoms of insomnia Open
Insomnia is often accompanied by excessive pre-sleep rumination. Such ruminative thinking is also associated with increased connectivity of the default mode network (DMN). It is likely that DMN connectivity and associated rumination contri…
View article: Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep in Individuals With Insomnia Symptoms: Protocol for a Double-Blind Randomized Controlled Trial (Preprint)
Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep in Individuals With Insomnia Symptoms: Protocol for a Double-Blind Randomized Controlled Trial (Preprint) Open
BACKGROUND Cortical hyperarousal and ruminative thinking are common aspects of insomnia that have been linked with greater connectivity in the default mode network (DMN). Therefore, disrupting network activity within the DMN may reduce co…
View article: Comparisons of Sleep, Demographics, and Health-Related Variables in Older Long and Average Duration Sleepers
Comparisons of Sleep, Demographics, and Health-Related Variables in Older Long and Average Duration Sleepers Open
Introduction Long sleep duration is associated with many health risks, particularly in older adults, but little is known about other characteristics associated with long sleep duration. Methods Across 5 sites, adults aged 60-80 years who r…
View article: 0066 Continuous Theta Burst Transcranial Magnetic Stimulation for Insomnia and its Effects on Verbal Recall Performance
0066 Continuous Theta Burst Transcranial Magnetic Stimulation for Insomnia and its Effects on Verbal Recall Performance Open
Introduction In this project, we studied the efficacy of focused inhibitory stimulation using continuous theta burst stimulation (cTBS) repetitive transcranial magnetic stimulation (rTMS) on an easily accessible region of the default mode …
View article: 0485 The clinical utility of echocardiography in identifying patients with heart failure at a single academic sleep center
0485 The clinical utility of echocardiography in identifying patients with heart failure at a single academic sleep center Open
Introduction Heart failure and sleep disordered breathing are prevalent in the United States and often co-exist; diagnostic strategy and management for sleep disordered breathing may change based on the presence, absence and type of heart …
View article: 0684 Effects of Transcranial Magnetic Stimulation (TMS) on Treatment of Intrusive Thinking in Insomniac Populations
0684 Effects of Transcranial Magnetic Stimulation (TMS) on Treatment of Intrusive Thinking in Insomniac Populations Open
Introduction Patients with clinical insomnia commonly report intrusive thinking (IT) as a common contributor to delayed sleep onset. Evidence suggests that the default mode network (DMN) may contribute to this intrusive thinking. Therefore…
View article: 0416 Preliminary Study of the Effects of Continuous Theta Burst Stimulation of the Default Mode Network on Subjective Sleepiness
0416 Preliminary Study of the Effects of Continuous Theta Burst Stimulation of the Default Mode Network on Subjective Sleepiness Open
Introduction Repetitive transcranial Magnetic Stimulation (rTMS) is a noninvasive intervention commonly used to treat clinical depression by modulating brain activity in specific regions. We investigated rTMS of the default mode network (D…
View article: 0441 Positive airway pressure therapy associated changes in ventricular repolarization in patients with heart failure
0441 Positive airway pressure therapy associated changes in ventricular repolarization in patients with heart failure Open
Introduction Obstructive sleep apnea (OSA) is associated with prolonged ventricular repolarization at baseline that further increases during sleep when an apnea/hypopnea event occurs. Aggressive treatment of OSA with positive airway pressu…
View article: 0186 Continuous Theta Burst Transcranial Magnetic Stimulation and Signal Detection Performance on a Military Go/No-Go Task
0186 Continuous Theta Burst Transcranial Magnetic Stimulation and Signal Detection Performance on a Military Go/No-Go Task Open
Introduction Repetitive transcranial Magnetic Stimulation (rTMS) is an emerging non-pharmacological treatment method utilized to treat multiple clinical diagnoses to include anxiety, depression, and now insomnia. As part of a larger projec…