Explanipedia

Multispectral Optoacoustic Tomography of Skeletal Muscle Unveils Microcirculation and Oxygen Metabolism Alterations in Sarcopenia Open

Ying Yang, Dan Wu, Y. Xv, Yonghua Xie, Xinsheng Wang , et al. · 2025

Background Sarcopenia, a significant geriatric syndrome, faces challenges in accurate diagnosis due to limitations of current imaging techniques. This study explores the novel application of multispectral optoacoustic tomography (MSOT) in …

Guanfacine for Treatment of Anxiety and Panic-Induced Vasovagal Syncope in the Intensive Care Unit Open

Shixie Jiang, Diego Nolasco, Richard Czuma, Brandon Janssen, Matthew Gunther · 2025

This case report describes the successful use of oral guanfacine, a centrally acting alpha-2 agonist, for treating panic-induced vasovagal syncope in a 68-year-old intensive care unit (ICU) patient recovering from lung transplant and cardi…

Catatonia: American Psychiatric Association Resource Document Open

Jo Ellen Wilson, Mark Oldham, Andrew Francis, Dina Perkey, Eric N. Kramer , et al. · 2025

The American Psychiatric Association Resource Document for Catatonia was prepared by the Catatonia Work Group of the Council on Consultation-Liaison Psychiatry, with the goal of supporting psychiatrists, trainees, and other mental healthca…

A Critical Reappraisal of Haloperidol for Delirium Management in the Intensive Care Unit: Perspective from Psychiatry Open

Shixie Jiang, Matthew Gunther · 2025

Delirium is a complex neuropsychiatric syndrome with multifactorial pathophysiology, encompassing a wide range of neuropsychiatric symptoms, and its management remains a significant challenge in critical care. Although often managed with a…

Investigating Sepsis-Associated Delirium Through Optical Neuroimaging: A New Frontier in Critical Care Research Open

Shixie Jiang, Matthew Gunther, José R. Maldonado, Philip A. Efron, Steven T. DeKosky , et al. · 2024

Sepsis is a life-threatening syndrome consisting of physiological, pathological, and biochemical abnormalities induced by infection which continues to be a major public health burden. It remains one of the most common reasons for intensive…

The triglyceride-glucose index and risk of cognitive impairment: a systematic review and meta-analysis with inclusion of two national databases Open

Ying Yang, Pai Peng, Hua‐Dong Huang, Yanan Zhao, Yating Li , et al. · 2024

Background To investigate the relationship between the triglyceride and glucose (TyG) index and cognitive impairment (CI). Methods Five authoritative databases were systematically searched for potentially relevant studies on ‘TyG index’ an…

Diffuse optical tomography for mapping cerebral hemodynamics and functional connectivity in delirium Open

Shixie Jiang, Jingyu Huang, Hao Yang, Richard Czuma, Lauren Farley , et al. · 2024

INTRODUCTION Delirium is associated with mortality and new onset dementia, yet the underlying pathophysiology remains poorly understood. Development of imaging biomarkers has been difficult given the challenging nature of imaging delirious…

Portable Diffuse Optical Tomography for Three-Dimensional Functional Neuroimaging in the Hospital Open

Jingyu Huang, Shixie Jiang, Hao Yang, Richard Czuma, Ying Yang , et al. · 2024

Functional neuroimaging studies of neuropsychiatric disorders and cognitive impairment are commonly conducted in the clinic setting but less so in the acutely medically ill while hospitalized. This is largely due to technical and logistica…

Nortriptyline-Induced Room Tilt Illusion Open

Bernard Sarmiento, Rojan Varghese, Richa Vijayvargia, Matthew Gunther, Adam J. Fusick , et al. · 2024

Room tilt illusion (RTI) is a rare and transient perceptual disturbance in which an individual perceives their surroundings as having been rotated or tilted, usually at 90 or 180 degrees. Primarily linked with vestibular disorders and neur…

Herba Epimedii and Increased Opioid Cravings While on Buprenorphine: A Case Report Open

Heather Burke, Bernard A Sarmiento, Matthew Gunther, Richard Czuma, Cory Klippel , et al. · 2024

Herba Epimedii, commonly known as yin yang huo, inyokaku, and horny goat weed, is a traditional Chinese herbal medicine utilized for treating osteoporosis and enhancing libido. Studies conducted in vitro have demonstrated that Herba Epimed…

Multispectral Optoacoustic Tomography of Skeletal Muscle Unveils Microcirculation and Oxygen Metabolism Alterations in Sarcopenia Open

Ying Yang, Dan Wu, Y. Xv, Yonghua Xie, Xinsheng Wang , et al. · 2024

Optical Neuroimaging in Delirium Open

Shixie Jiang, Philip A. Efron, Esther S. Oh, Steven T. DeKosky · 2023

Delirium persists as the most common neuropsychiatric syndrome among medically ill hospitalized patients, yet its neural mechanisms remain poorly understood. The development of neuroimaging biomarkers has been difficult primarily due to th…

Photoacoustic Tomography Combined with Ultrasound Mapping for Guiding Fine-Needle Aspiration of Thyroid Nodules: A Pilot Study Open

Yanting Wen, Dan Wu, Xiaotian Liu, Yonghua Xie, Jing Zhang , et al. · 2023

This study aims to explore the feasibility of fine-needle aspiration biopsy (FNAB) under dual modal photoacoustic tomography(PAT)/ultrasound (US) imaging. A total of 25 patients who have thyroid nodules with thyroid imaging reporting and d…

The impact of triglyceride-glucose index on ischemic stroke: a systematic review and meta-analysis Open

Ying Yang, Xiangting Huang, Yuge Wang, Lin Leng, Jiapei Xu , et al. · 2023

A Retrospective Analysis of Guanfacine for the Pharmacological Management of Delirium Open

Shixie Jiang, Michael Hernandez, Heather Burke, Benjamin Spurling, Richard Czuma , et al. · 2023

Background Delirium is a syndrome of acute brain failure that represents a change from an individual's baseline cognitive functioning characterized by deficits in attention and multiple aspects of cognition that fluctuate in severity over …

Clinical photoacoustic/ultrasound dual-modal imaging: Current status and future trends Open

Yanting Wen, Dan Guo, Jing Zhang, Xiaotian Liu, Ting Liu , et al. · 2022

Photoacoustic tomography (PAT) is an emerging biomedical imaging modality that combines optical and ultrasonic imaging, providing overlapping fields of view. This hybrid approach allows for a natural integration of PAT and ultrasound (US) …

Optical neuroimaging: advancing transcranial magnetic stimulation treatments of psychiatric disorders Open

Shixie Jiang, Linda L. Carpenter, Huabei Jiang · 2022

Evaluation of Tracheal Stenosis in Rabbits Using Multispectral Optoacoustic Tomography Open

Yanting Wen, Dan Wu, Jing Zhang, Shixie Jiang, Chunyan Xiong , et al. · 2022

Objective: Photoacoustic tomography (PAT) and multispectral optoacoustic tomography (MSOT) are evolving technologies that are capable of delivering real-time, high-resolution images of tissues. The purpose of this study was to evaluate the…

Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis Open

Tao Zhang, Yan Ren, Shen Ping, Shixie Jiang, Yanrong Yang , et al. · 2022

Objective Currently, the prevalence of CF (Cognitive Frailty) is not very clear, and the relationship between CF and its associated risk factors has not been accurately evaluated. Therefore, it is necessary to conduct a systematic review a…

Neuroimaging of depression with diffuse optical tomography during repetitive transcranial magnetic stimulation Open

Shixie Jiang, Jingyu Huang, Hao Yang, Ryan Wagoner, F. Andrew Kozel , et al. · 2021

Inside Cover: In‐vivo hemodynamic imaging of acute prenatal ethanol exposure in fetal brain by photoacoustic tomography (J. Biophotonics 5/2020) Open

Tianqi Shan, Yuan Zhao, Shixie Jiang, Huabei Jiang · 2020

The figure shows the detailed morphology of vasculature and dynamic changes of the blood vessel diameter and density and the oxygen saturation in the blood vessels in fetal brain after acute prenatal ethanol exposure in the second‐trimeste…

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