Shuhong Guan
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View article: Combined Detection of Tumor Stem Cell Markers CD133 and OCT4 in Early Non-Small Cell Lung Cancer Screening and Prognostic Evaluation
Combined Detection of Tumor Stem Cell Markers CD133 and OCT4 in Early Non-Small Cell Lung Cancer Screening and Prognostic Evaluation Open
CD133 and OCT4 are overexpressed in early-stage NSCLC and are associated with aggressive disease and poor prognosis. Combined detection provides superior diagnostic accuracy (AUC=0.893) compared to single markers and may serve as a valuabl…
View article: Soil nitrogen-hydrolyzing enzyme activities respond differently to the freeze-thaw temperature and number of cycles
Soil nitrogen-hydrolyzing enzyme activities respond differently to the freeze-thaw temperature and number of cycles Open
Soil nitrogen-hydrolyzing enzymes catalyzes a key rate-limiting step in regulating the circulation of soil nutrient elements. The response of soil nitrogen (N)-hydrolyzing enzyme activities to environmental changes has been investigated in…
View article: Impact of biopsy number and radiologic pattern on diagnostic yield and complications of transbronchial lung cryobiopsy in interstitial lung diseases: a multi-center retrospective study
Impact of biopsy number and radiologic pattern on diagnostic yield and complications of transbronchial lung cryobiopsy in interstitial lung diseases: a multi-center retrospective study Open
This study showed that obtaining three biopsy samples is appropriate to achieve an adequate diagnostic yield, while procedure methods are associated with complications. Further well-designed studies are required to standardize TBLC procedu…
View article: Macrocyclic Diterpenoids from Euphorbia peplus Possessing Activity Towards Autophagic Flux
Macrocyclic Diterpenoids from Euphorbia peplus Possessing Activity Towards Autophagic Flux Open
Euphjatrophanes H–L (1–5), four new jatrophane-type and one new lathyrane-type diterpenoid, were isolated from Euphorbia peplus, along with eight known diterpenoids (6–13). Their structures were established on the basis of extensive spectr…
View article: Pathogenic screening and disease prevention of thrombophilia based on radiation CT imaging examination
Pathogenic screening and disease prevention of thrombophilia based on radiation CT imaging examination Open
View article: Diagnostic value of rEBUS-TBLB combined distance measurement method based on ultrasound images in bronchoscopy for peripheral lung lesions
Diagnostic value of rEBUS-TBLB combined distance measurement method based on ultrasound images in bronchoscopy for peripheral lung lesions Open
Traditional imaging methods have limitations in the diagnosis of peripheral lung lesions. The aim of this study is to evaluate the diagnostic value of the distance measurement method based on ultrasound image-based inverted electrostrain (…
View article: Comparison of radial endobronchial ultrasound-guided transbronchial lung biopsy with distance measurement versus with guide sheath in diagnosing peripheral pulmonary lesions with a diameter ≥3 cm by thin bronchoscope
Comparison of radial endobronchial ultrasound-guided transbronchial lung biopsy with distance measurement versus with guide sheath in diagnosing peripheral pulmonary lesions with a diameter ≥3 cm by thin bronchoscope Open
OBJECTIVE: This study aims to explore the diagnostic values of radial endobronchial ultrasound-guided transbronchial lung biopsy with distance (rEBUS-D-TBLB) measurement and with guide sheath (rEBUS-GS-TBLB) for peripheral pulmonary lesion…
View article: Analysis of indications for pulmonary peripheral lesions diagnosed using radial endobronchial ultrasound‑guided transbronchial lung biopsy
Analysis of indications for pulmonary peripheral lesions diagnosed using radial endobronchial ultrasound‑guided transbronchial lung biopsy Open
The aim of the present study was to determine the indications for radial endobronchial ultrasound-guided transbronchial lung biopsy (rEBUS-D-TBLB) for the diagnosis of peripheral pulmonary lesions (PPL) located at the bronchopulmonary segm…
View article: TGF‑β1 induces CREB1‑mediated miR‑1290 upregulation to antagonize lung fibrosis via Napsin�A
TGF‑β1 induces CREB1‑mediated miR‑1290 upregulation to antagonize lung fibrosis via Napsin�A Open
The pathologic mechanisms of pulmonary fibrosis (PF), one of the most common chronic pulmonary diseases, remain unclear. Napsin A is an aspartic proteinase that has been regarded as a hallmark of pulmonary adenocarcinoma. The present study …
View article: IL-33/ST2 pathway in a bleomycin-induced pulmonary fibrosis model
IL-33/ST2 pathway in a bleomycin-induced pulmonary fibrosis model Open
The present study aimed to investigate the interleukin (IL)‑33/ST2 pathway in a model of acute pulmonary fibrosis, and to examine the pathogenesis of pulmonary fibrosis. The pulmonary fibrosis model was established by a single exposure to …