Shu‐Yi Yin
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View article: HDAC2-mediated chromatin remodeling drives hepatocellular carcinoma progression: an integrative analysis of computational pathology and multi-transcriptomics
HDAC2-mediated chromatin remodeling drives hepatocellular carcinoma progression: an integrative analysis of computational pathology and multi-transcriptomics Open
View article: Predictive value of tumor-infiltrating lymphocytes combined with tumor-stromal ratio for axillarylymph node metastasis in breast cancer patients - a retrospective cohort study
Predictive value of tumor-infiltrating lymphocytes combined with tumor-stromal ratio for axillarylymph node metastasis in breast cancer patients - a retrospective cohort study Open
View article: Study on the Application of Serological Indexes Based on Machine Learning in Non-invasive Detection of Liver Fibrosis
Study on the Application of Serological Indexes Based on Machine Learning in Non-invasive Detection of Liver Fibrosis Open
This study aims to develop a non-invasive detection method for liver fibrosis using machine learning, predicting the serological markers of patients with liver fibrosis. The study first screened out characteristic variables through data pr…
View article: Papillary renal neoplasm with reverse polarity: an observational study of histology, immunophenotypes, and molecular variation
Papillary renal neoplasm with reverse polarity: an observational study of histology, immunophenotypes, and molecular variation Open
These findings suggested that PRNRP is a distinctive subtype of renal tumor with specific pathological features and indolent behaviors that should be distinguished from other renal tumors, especially papillary renal cell carcinoma. A monol…
View article: A Grading System of Microvascular Invasion for Patients with Hepatocellular Carcinoma Undergoing Liver Resection with Curative Intent: A Multicenter Study
A Grading System of Microvascular Invasion for Patients with Hepatocellular Carcinoma Undergoing Liver Resection with Curative Intent: A Multicenter Study Open
This MVI grading system could precisely evaluate prognosis of HCC patients after liver resection with curative intent and it could be employed in routine pathological reports. The severity of MVI from both adjacent and distant from tumor b…
View article: SAMHD1 Mutations and Expression in Mantle Cell Lymphoma Patients
SAMHD1 Mutations and Expression in Mantle Cell Lymphoma Patients Open
SAMHD1 (sterile alpha motif domain and histidine-aspartate domain-containing protein 1) is a deoxynucleoside triphosphate triphosphohydrolase regulating innate immune and modulating DNA damage signaling. It plays an important role in the d…
View article: Transcriptomic analysis reveals a controlling mechanism for NLRP3 and IL-17A in dextran sulfate sodium (DSS)-induced colitis
Transcriptomic analysis reveals a controlling mechanism for NLRP3 and IL-17A in dextran sulfate sodium (DSS)-induced colitis Open
View article: Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based Vaccine
Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based Vaccine Open
Suppression of tumor metastasis is a key strategy for successful cancer interventions. Previous studies indicated that rapamycin (sirolimus) may promote tumor regression activity or enhance immune response against tumor targets. However, r…
View article: Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components
Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components Open
Our findings on the differential roles or effect of various ICD components in activating vaccinated DCs may help formulate new strategies for future cancer vaccine designs.
View article: Mechanistic Study of the Phytocompound, 2-<i>β</i>-D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches
Mechanistic Study of the Phytocompound, 2-<i>β</i>-D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches Open
Bidens pilosa , a medicinal herb worldwide, is rich in bioactive polyynes. In this study, by using high resolution 2-dimensional gel electrophoresis coupled with mass spectrometry analysis, as many as 2000 protein spots could be detected a…