Sho Osawa
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View article: Usefulness of Frameless Neuronavigation–Guided Stereotactic Biopsy for Brain Lesions Under Local Anesthesia: Surgical Outcomes and Feasibility for Molecular Diagnosis—Case Series
Usefulness of Frameless Neuronavigation–Guided Stereotactic Biopsy for Brain Lesions Under Local Anesthesia: Surgical Outcomes and Feasibility for Molecular Diagnosis—Case Series Open
BACKGROUND AND OBJECTIVES: Frameless neuronavigation–guided stereotactic biopsy (SB) is a common surgical technique for diagnosing intracranial lesions. A frameless SB is generally performed under general anesthesia; however, no reports ar…
View article: One-stage Surgery for Malignant Skull and Scalp Tumor: Navigation-guided Tumor Resection and Cranioplasty Using Custom-made Implants: Technical Note
One-stage Surgery for Malignant Skull and Scalp Tumor: Navigation-guided Tumor Resection and Cranioplasty Using Custom-made Implants: Technical Note Open
One-stage tumor resection and cranioplasty for skull tumors using custom-made implants are beneficial for reducing patient burden, minimizing complications, and improving cosmetic outcomes. However, accurately determining the craniotomy li…
View article: 10048- COT-5 DEVELOPMENT OF A DIAGNOSTIC MODEL FOR GLIOMAS USING SERUM MICRO RNA
10048- COT-5 DEVELOPMENT OF A DIAGNOSTIC MODEL FOR GLIOMAS USING SERUM MICRO RNA Open
BACKGROUND MicroRNAs (miRNAs) are non-coding RNAs consisting of approximately 20 base pairs. Several studies have reported the usefulness of serum miRNAs in the diagnosis of gliomas. However, the results differ among studies, and reproduci…
View article: Delayed Deep White Matter Ischemia After Resection of Gliomas by Awake Surgery
Delayed Deep White Matter Ischemia After Resection of Gliomas by Awake Surgery Open
BACKGROUND AND OBJECTIVES: Deep white matter (DWM) is perfused by the medullary arteries from the cortex, and ischemia sometimes occurs after glioma resection. However, the clinical significance of postoperative medullary artery–related is…
View article: Novel case of anastomosing hemangioma of the extradural space: illustrative case
Novel case of anastomosing hemangioma of the extradural space: illustrative case Open
BACKGROUND Anastomosing hemangiomas are benign vascular neoplasms occurring mainly in the genitourinary tract and paraspinal soft tissues. There have been no reported cases of anastomosing hemangiomas occurring in the spinal epidural space…
View article: Risk Factors of Distant Recurrence and Dissemination of IDH Wild-Type Glioblastoma: A Single-Center Study and Meta-Analysis
Risk Factors of Distant Recurrence and Dissemination of IDH Wild-Type Glioblastoma: A Single-Center Study and Meta-Analysis Open
Isocitrate dehydrogenase (IDH) wild-type glioblastoma (GBM) is a highly aggressive brain tumor with a high recurrence rate despite adjuvant treatment. This study aimed to evaluate the risk factors for non-local recurrence of GBM. In the pr…
View article: Pediatric atypical teratoid/rhabdoid tumor in the cauda equina with rapid tumor progression: illustrative case
Pediatric atypical teratoid/rhabdoid tumor in the cauda equina with rapid tumor progression: illustrative case Open
BACKGROUND Atypical teratoid/rhabdoid tumor (AT/RT) is an uncommon malignant neoplasm and rarely occurs in the spinal space, especially in the cauda equina. Only 8 cases of pediatric AT/RT of the cauda equina have been reported. Therefore,…
View article: Resection and postoperative pazopanib for intraspinal recurrent solitary fibrous tumor: illustrative case
Resection and postoperative pazopanib for intraspinal recurrent solitary fibrous tumor: illustrative case Open
BACKGROUND Intracranial solitary fibrous tumors (SFTs) rarely recur in the spinal space. Only 4 cases of spinal recurrence from intracranial SFT have been reported; therefore, the optimal treatment of recurrent spinal SFT remains unclear. …
View article: The Safety and Usefulness of Awake Surgery as a Treatment Modality for Glioblastoma: A Retrospective Cohort Study and Literature Review
The Safety and Usefulness of Awake Surgery as a Treatment Modality for Glioblastoma: A Retrospective Cohort Study and Literature Review Open
Awake surgery contributes to the maximal safe removal of gliomas by localizing brain function. However, the efficacy and safety thereof as a treatment modality for glioblastomas (GBMs) have not yet been established. In this study, we analy…
View article: Pediatric atypical teratoid/rhabdoid tumor in the cauda equina with rapid tumor progression: A case report and review of the literature
Pediatric atypical teratoid/rhabdoid tumor in the cauda equina with rapid tumor progression: A case report and review of the literature Open
Atypical teratoid/rhabdoid tumors (AT/RT) rarely occur in the cauda equina; thus, the clinical behavior and optimal treatment remain unclear. A 9-year-old boy presented with a rapidly progressing intradural extramedullary tumor at the L2–5…
View article: Development of a scoring system to predict local recurrence in brain metastases following complete resection and observation
Development of a scoring system to predict local recurrence in brain metastases following complete resection and observation Open
Purpose Postoperative careful radiological observation could be a therapeutic option in patients with brain metastases after complete resection. However, there are no clear criteria to determine this indication. We investigated risk factor…
View article: 10115-STMO-4 SURGICAL OUTCOMES OF AWAKE SURGERY FOR GLIOBLASTOMA
10115-STMO-4 SURGICAL OUTCOMES OF AWAKE SURGERY FOR GLIOBLASTOMA Open
OBJECTIVE Awake surgery contributes to maximal resection of brain tumors and preservation of brain function. In this study, we investigated the surgical outcomes, efficacy and safety of awake surgery for glioblastoma (GBM) at our instituti…
View article: 10109-COT-13 LONG-TERM FOLLOW-UP OF FLAIR HIGH LESION IN THE BRAIN
10109-COT-13 LONG-TERM FOLLOW-UP OF FLAIR HIGH LESION IN THE BRAIN Open
AIM Incidental FLAIR (Fluid Attenuated Inversion Recovery) high-intensity lesion in the brain can be considered as IDH-mutant low-grade glioma (LGG). Differential diagnosis includes trauma, ischemic changes, demyelinating diseases, and oth…
View article: 10162-STMO-8 A SINGLE CENTER RETROSPECTIVE ANALYSIS OF AWAKE CRANIOTOMY FOR BRAIN METASTASIS.
10162-STMO-8 A SINGLE CENTER RETROSPECTIVE ANALYSIS OF AWAKE CRANIOTOMY FOR BRAIN METASTASIS. Open
BACKGROUND/AIM Awake surgery is often used for resecting glioma, but it is controversial whether it should be performed for brain metastasis, because brain tumor is rather demarcated than glioma. However, a small number of hospitals can pe…
View article: 10126-ACT-10 FACTORS AFFECTING THE PATTERN OF RECURRENCE OF IDH-WILDTYPE GLIOBLASTOMA
10126-ACT-10 FACTORS AFFECTING THE PATTERN OF RECURRENCE OF IDH-WILDTYPE GLIOBLASTOMA Open
INTRODUCTION IDH-wildtype glioblastoma is a quite poor prognosis disease with which almost all cases recur in spite of postoperative radiation and chemotherapy. Survival rates are particularly low after dissemination. METHODS We included 1…
View article: NI-2 DUAL-ISOTOPE 123I-IMP/201TL SPECT FOR THE DIFFERENTIAL DIAGNOSIS OF PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA AND GLIOBLASTOMA
NI-2 DUAL-ISOTOPE 123I-IMP/201TL SPECT FOR THE DIFFERENTIAL DIAGNOSIS OF PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA AND GLIOBLASTOMA Open
Background Preoperative differential diagnosis between primary central nervous system lymphoma (PCNSL) and glioblastoma (GBM) is important because these tumors require different surgical strategies. This study investigated the usefulness o…
View article: Usefulness of Dual Isotope 123I-IMP and 201Tl SPECT for the Diagnosis of Primary Central Nervous System Lymphoma and Glioblastoma
Usefulness of Dual Isotope 123I-IMP and 201Tl SPECT for the Diagnosis of Primary Central Nervous System Lymphoma and Glioblastoma Open
IntroductionPreoperative differential diagnosis between glioblastoma (GBM) and primary central nervous system lymphoma (PCNSL) is important because these tumors require different surgical strategies. This study investigated the usefulness …
View article: ML-18 Clinical diagnosis for suspected primary central nervous system lymphoma patients without histopathological confirmation
ML-18 Clinical diagnosis for suspected primary central nervous system lymphoma patients without histopathological confirmation Open
Background: The gold standard of the diagnosis of primary central nervous system lymphoma (PCNSL) is the histopathological diagnosis by biopsy surgery. However, we experience some cases with a high risk of biopsy surgery or difficulty in g…
View article: Predictors of Discontinuance of Oral Feeding in Patients With Advanced Alzheimer Dementia and Aspiration Pneumonia in Japan
Predictors of Discontinuance of Oral Feeding in Patients With Advanced Alzheimer Dementia and Aspiration Pneumonia in Japan Open
Background: Difficulty with oral feeding, the most commonly observed complication of Alzheimer disease (AD) in its final stages, occurs in 86% of AD patients and may prevent achievement of oral feeding after aspiration pneumonia. However, …
View article: 甲状腺ホルモン受容体仲介機能に対する環境化学物質,4-ノニルフェノールの誘導効果
甲状腺ホルモン受容体仲介機能に対する環境化学物質,4-ノニルフェノールの誘導効果 Open
View article: The possible inducing effect of an environmental chemical, 4-nonyl Phenol, on the thyroid hormone receptor-mediated function
The possible inducing effect of an environmental chemical, 4-nonyl Phenol, on the thyroid hormone receptor-mediated function Open