Shota Yokoyama
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View article: Comparable outcomes with 14-, 21-, or standard 28-day venetoclax in the first cycle of azacitidine–venetoclax in untreated acute myeloid leukemia: real-world experience from the Hokkaido Leukemia Net
Comparable outcomes with 14-, 21-, or standard 28-day venetoclax in the first cycle of azacitidine–venetoclax in untreated acute myeloid leukemia: real-world experience from the Hokkaido Leukemia Net Open
View article: High-Entropy Alloy Al0.2Co1.5CrFeNi1.5Ti0.5 Prepared from High-Entropy Oxide (Al0.2Co1.5CrFeNi1.5Ti0.5)3O4 by a Deoxidation Process via a CaH2-Assisted Molten Salt Method
High-Entropy Alloy Al0.2Co1.5CrFeNi1.5Ti0.5 Prepared from High-Entropy Oxide (Al0.2Co1.5CrFeNi1.5Ti0.5)3O4 by a Deoxidation Process via a CaH2-Assisted Molten Salt Method Open
High-entropy alloys (HEAs) have attracted a great deal of research interest these days because of their attractive properties. Low-temperature chemical synthesis methods are being developed to obtain nanoscale HEAs with low energy consumpt…
View article: Efficacy and Safety of Single-dose Pegfilgrastim for CD34+ Cell Mobilization in Healthy Volunteers: A Phase 2 Study
Efficacy and Safety of Single-dose Pegfilgrastim for CD34+ Cell Mobilization in Healthy Volunteers: A Phase 2 Study Open
Background. Pegfilgrastim, a long-acting form of granulocyte-colony stimulating factor, with a convenient single-injection dosage, is being investigated for peripheral blood stem cell (PBSC) mobilization in healthy volunteers. However, dat…
View article: P1414: CRP IS A CONVENIENT PREDICTIVE MARKER OF THE ANTIPYRETIC EFFECT OF TOCILIZUMAB ON CRS DURING CAR-T CELL THERAPY
P1414: CRP IS A CONVENIENT PREDICTIVE MARKER OF THE ANTIPYRETIC EFFECT OF TOCILIZUMAB ON CRS DURING CAR-T CELL THERAPY Open
Topic: 25. Gene therapy, cellular immunotherapy and vaccination - Clinical Background: Cytokine release syndrome (CRS) is an important adverse event in chimeric antigen receptor (CAR)-T cell therapy. Tocilizumab (TCZ), an anti-IL-6 recepto…
View article: P1526: THE RISK OF DEVELOPING PNEUMOCYSTIS JIROVECII PNEUMONIA PERSISTS EVEN AFTER COMPLETION OF IMMUNOSUPPRESSANTS IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION RECIPIENTS
P1526: THE RISK OF DEVELOPING PNEUMOCYSTIS JIROVECII PNEUMONIA PERSISTS EVEN AFTER COMPLETION OF IMMUNOSUPPRESSANTS IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION RECIPIENTS Open
Topic: 30. Infections in hematology (incl. supportive care/therapy) Background:Pneumocystis jirovecii pneumonia (PjP) is a life-threatening infection in allogeneic hematopoietic stem cell transplantation (allo-SCT) recipients. Trimethoprim…
View article: On the regularization and optimization in quantum detector tomography
On the regularization and optimization in quantum detector tomography Open
View article: Catalytic Hydrogenation of Methyl Orange and Acid Orange 7 Using NaBH<sub>4</sub> over Core-shell Multicomponent Alloys
Catalytic Hydrogenation of Methyl Orange and Acid Orange 7 Using NaBH<sub>4</sub> over Core-shell Multicomponent Alloys Open
Azo dyes are common aqueous environmental pollutants in developing countries. Hydrogenation is a highly effective method for decomposition of azo dyes; however, this method requires the use of noble metals as catalysts. In this study, we i…
View article: Molten salt synthesis of CrMnFeNi alloy nanopowder passivated by TiO<sub><i>x</i></sub>–ZrO<sub><i>y</i></sub> shell used as a superior catalyst support in liquid-phase hydrogenation
Molten salt synthesis of CrMnFeNi alloy nanopowder passivated by TiO<sub><i>x</i></sub>–ZrO<sub><i>y</i></sub> shell used as a superior catalyst support in liquid-phase hydrogenation Open
The enhancement of liquid-phase hydrogenation by NaBH 4 over Ni-loaded CrMnFeNi alloy nanoparticles passivated by TiO x –ZrO y .
View article: Molten Salt Synthesis of Intermetallic Compound TiNi Nanopowder Passivated by TiOx Shell Prepared from NiTiO3 for Catalytic Hydrogenation
Molten Salt Synthesis of Intermetallic Compound TiNi Nanopowder Passivated by TiOx Shell Prepared from NiTiO3 for Catalytic Hydrogenation Open
Titanium-nickel alloy is an attractive material due to its unique properties of shape memory effect, superior elasticity, and biocompatibility. Generally, Ti-Ni alloy powders are prepared from pure elemental powders of Ti and Ni as startin…
View article: Antiretroviral therapy achieved metabolic complete remission of hepatic AIDS related Epstein-Barr virus-associated smooth muscle tumor
Antiretroviral therapy achieved metabolic complete remission of hepatic AIDS related Epstein-Barr virus-associated smooth muscle tumor Open
Epstein-Barr virus-associated smooth muscle tumor (EBV-SMT) is a rare mesenchymal tumor which occurs in immunocompromised patients. The immune status is an important factor in the treatment of EBV-SMTs, but the efficacy of antiretroviral t…
View article: On the regularization and optimization in quantum detector tomography
On the regularization and optimization in quantum detector tomography Open
Quantum detector tomography (QDT) is a fundamental technique for calibrating quantum devices and performing quantum engineering tasks. In this paper, we utilize regularization to improve the QDT accuracy whenever the probe states are infor…
View article: High CRP-albumin ratio predicts poor prognosis in transplant ineligible elderly patients with newly diagnosed acute myeloid leukemia
High CRP-albumin ratio predicts poor prognosis in transplant ineligible elderly patients with newly diagnosed acute myeloid leukemia Open
Acute myeloid leukemia (AML) patients older than 65 years have a poor prognosis. Recently, CAR (C-reactive-protein/albumin ratio) has been actively reported as a prognostic index reflecting the nutritional and inflammatory status of elderl…
View article: Perinatal Management in a Pregnant Woman with Ureteropelvic Junction Obstruction: Case Report and Literature Review
Perinatal Management in a Pregnant Woman with Ureteropelvic Junction Obstruction: Case Report and Literature Review Open
Although giant hydronephrosis (GH) associated with ureteropelvic junction obstruction (UPJO) is extremely rarely detected in pregnant women, diagnostic methods, therapeutic approaches, and perinatal management have not been established. A …
View article: Simultaneous estimation of parameters and the state of an optical parametric oscillator system
Simultaneous estimation of parameters and the state of an optical parametric oscillator system Open
In this paper, we consider the filtering problem of an optical parametric oscillator (OPO). The OPO pump power may fluctuate due to environmental disturbances, resulting in uncertainty in the system modeling. Thus, both the state and the u…
View article: Simultaneous estimation of parameters and the state of an optical\n parametric oscillator system
Simultaneous estimation of parameters and the state of an optical\n parametric oscillator system Open
In this paper, we consider the filtering problem of an optical parametric\noscillator (OPO). The OPO pump power may fluctuate due to environmental\ndisturbances, resulting in uncertainty in the system modeling. Thus, both the\nstate and th…
View article: Association between physical restraint requirement and unfavorable neurologic outcomes in subarachnoid hemorrhage
Association between physical restraint requirement and unfavorable neurologic outcomes in subarachnoid hemorrhage Open
Background Physical restraint has been commonly indicated to patients with brain dysfunction in neurocritical care. The effect of physical restraints on outcomes of critically ill adults remains controversial as no randomized controlled tr…
View article: Progression of cervical intraepithelial neoplasia grade 2 lesions among Japanese women harboring different genotype categories of high-risk human papillomaviruses
Progression of cervical intraepithelial neoplasia grade 2 lesions among Japanese women harboring different genotype categories of high-risk human papillomaviruses Open
Background: This study aimed to examine whether genotype categories of high-risk human papillomaviruses (HR-HPVs), when divided into HPV16/18, HPV 31/33/45/52/58, and HPV35/39/51/56/59/68, had an effect on the time required for and …
View article: Time Course Changes in Urinary Angiotensinogen and Circulating N-Terminal Pro-B-Type Natriuretic Peptide in Patients Hospitalized with Acute Heart Failure
Time Course Changes in Urinary Angiotensinogen and Circulating N-Terminal Pro-B-Type Natriuretic Peptide in Patients Hospitalized with Acute Heart Failure Open
Objective Home care is important in patients with heart failure (HF) in order to maintain their quality of life. A biomarker that can be measured noninvasively is needed to optimize the home care of patients with HF. Urinary angiotensinoge…
View article: A novel nutritional index “simplified CONUT” and the disease risk index independently stratify prognosis of elderly patients with acute myeloid leukemia
A novel nutritional index “simplified CONUT” and the disease risk index independently stratify prognosis of elderly patients with acute myeloid leukemia Open
Elderly patients aged 65 or older with acute myeloid leukemia (AML) have poor prognosis. The risk stratification based on genetic alteration has been proposed in national comprehensive cancer network (NCCN) guideline but its efficacy was n…
View article: Association of physical restraint requirement with unfavorable neurologic outcomes in subarachnoid hemorrhage
Association of physical restraint requirement with unfavorable neurologic outcomes in subarachnoid hemorrhage Open
Background The association between physical restraint requirement and neurological outcome in patients with subarachnoid hemorrhage (SAH) has not been fully examined. The aim of this study was to examine the association between physical re…
View article: Letter to the Editor. Is time-weighted PaO₂ during the hyperacute phase of aneurysmal subarachnoid hemorrhage really helpful in usual care settings?
Letter to the Editor. Is time-weighted PaO₂ during the hyperacute phase of aneurysmal subarachnoid hemorrhage really helpful in usual care settings? Open
"Letter to the Editor. Is time-weighted PaO₂ during the hyperacute phase of aneurysmal subarachnoid hemorrhage really helpful in usual care settings?" published on 10 Apr 2020 by American Association of Neurological Surgeons.
View article: (−)-Epigallocatechin gallate inhibits stemness and tumourigenicity stimulated by AXL receptor tyrosine kinase in human lung cancer cells
(−)-Epigallocatechin gallate inhibits stemness and tumourigenicity stimulated by AXL receptor tyrosine kinase in human lung cancer cells Open
View article: Anagrelide Modulates Proplatelet Formation Resulting in Decreased Number and Increased Size of Platelets
Anagrelide Modulates Proplatelet Formation Resulting in Decreased Number and Increased Size of Platelets Open
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View article: Association of abnormal carbon dioxide levels with poor neurological outcomes in aneurysmal subarachnoid hemorrhage: a retrospective observational study
Association of abnormal carbon dioxide levels with poor neurological outcomes in aneurysmal subarachnoid hemorrhage: a retrospective observational study Open
Both the maximum and minimum PaCO2 levels during ICU management in patients with SAH were significantly associated with unfavorable neurological outcomes. Further prospective studies are required to validate our findings and exp…
View article: Early Hyperoxia in The Intensive Care Unit is Significantly Associated With Unfavorable Neurological Outcomes in Patients With Mild-to-Moderate Aneurysmal Subarachnoid Hemorrhage
Early Hyperoxia in The Intensive Care Unit is Significantly Associated With Unfavorable Neurological Outcomes in Patients With Mild-to-Moderate Aneurysmal Subarachnoid Hemorrhage Open
Introduction: Although oxygen administration is fundamental in the management of aneurysmal subarachnoid hemorrhage (SAH) patients in the acute stage, hyperoxia has harmful effects. The effects of hyperoxia on neurological outcomes in SAH …
View article: Cell softening in malignant progression of human lung cancer cells by activation of receptor tyrosine kinase AXL
Cell softening in malignant progression of human lung cancer cells by activation of receptor tyrosine kinase AXL Open
View article: Urban-Design Process with Snow and Wind Simulations: A Study on the Kitami City Hall
Urban-Design Process with Snow and Wind Simulations: A Study on the Kitami City Hall Open
Regional climatic conditions should be considered while designing urban development plans, with special attention to the impact of snowfall on public spaces in cities with harsh winters.The Kitami-city-hall-renewal project in Hokkaido, Jap…
View article: Factors Influencing the Appearance of Oxaliplatin-Induced Allergy
Factors Influencing the Appearance of Oxaliplatin-Induced Allergy Open
Several studies reported that the administration of oxaliplatin often induced allergy, but few studies have analyzed the pathogenesis. In this study, we examined the relationship between the incidence of allergy and status of oxaliplatin a…
View article: Investigation of Risk Factors Affecting Lactate Levels in Japanese Patients Treated with Metformin
Investigation of Risk Factors Affecting Lactate Levels in Japanese Patients Treated with Metformin Open
Metformin is a biguanaide antidiabetic drug used worldwide, and its effectiveness and benefits have already been established. However, the safety of high doses of metformin in Japanese patients, especially in elderly patients with a decrea…
View article: MyD88-deficiency did not affect body weight, adiposity, food intake or locomotor activities.
MyD88-deficiency did not affect body weight, adiposity, food intake or locomotor activities. Open
(A) Body weight gain was measured in control and MyD88-deficient mice. Both genotypes were fed a NCD until 6 weeks of age and then fed a NCD or HFD for 10 weeks. NCD (n = 21–29) and HFD (n = 20–26)-fed mice were examined at the age …