Shoujing Guo
YOU?
Author Swipe
View article: Development of an image-guided non-vitrectomy subretinal access approach for trans-scleral cell and gene therapy delivery
Development of an image-guided non-vitrectomy subretinal access approach for trans-scleral cell and gene therapy delivery Open
Purpose Regenerative therapies for retinal diseases include cell and gene therapy modalities that are targeted to the subretinal space. Several recent clinical trials have shown that the morbidity of surgical access is the major limitation…
View article: Common-path optical coherence tomography guided vertical pneumodissection for DALK
Common-path optical coherence tomography guided vertical pneumodissection for DALK Open
We reported a design and evaluation of an optical coherence tomography (OCT) sensor-integrated 27 gauge vertically inserted razor edge cannula (VIREC) for pneumatic dissection of Descemet's membrane (DM) from the stromal layer. The VIREC w…
View article: Convolutional neural network-based common-path optical coherence tomography A-scan boundary-tracking training and validation using a parallel Monte Carlo synthetic dataset
Convolutional neural network-based common-path optical coherence tomography A-scan boundary-tracking training and validation using a parallel Monte Carlo synthetic dataset Open
We present a parallel Monte Carlo (MC) simulation platform for rapidly generating synthetic common-path optical coherence tomography (CP-OCT) A-scan image dataset for image-guided needle insertion. The computation time of the method has be…
View article: Downward viewing common-path optical coherence tomography guided hydro-dissection needle for DALK
Downward viewing common-path optical coherence tomography guided hydro-dissection needle for DALK Open
Deep anterior lamellar keratoplasty (DALK) is a partial-thickness cornea transplant procedure in which only the recipient's stroma is replaced, leaving the host's Descemet's membrane (DM) and endothelium intact. This highly challenging "Bi…
View article: A Novel Wax Based Piezo Actuator for Autonomous Deep Anterior Lamellar Keratoplasty (Piezo-DALK)
A Novel Wax Based Piezo Actuator for Autonomous Deep Anterior Lamellar Keratoplasty (Piezo-DALK) Open
This paper reports the design and evaluation of a novel piezo based actuator for needle drive in autonomous Deep Anterior Lamellar Keratoplasty (piezo-DALK). The actuator weighs less than 8g and is 20mm × 20mm × 10.5mm in size, making it i…
View article: Optimized OCT-based depth-resolved model for attenuation compensation using point-spread-function calibration
Optimized OCT-based depth-resolved model for attenuation compensation using point-spread-function calibration Open
Optical coherence tomography (OCT) with a robust depth-resolved attenuation compensation method for a wide range of imaging applications is proposed and demonstrated. The proposed novel OCT attenuation compensation algorithm introduces an …
View article: Convolutional Neural Network-based Optical Coherence Tomography (OCT) A-scan Segmentation and Tracking Platform using Advanced Monte Carlo Simulation
Convolutional Neural Network-based Optical Coherence Tomography (OCT) A-scan Segmentation and Tracking Platform using Advanced Monte Carlo Simulation Open
We reported a parallel Monte Carlo simulation platform for generating OCT cornea images and training the convolutional neural network. The trained network showed improved segmentation results when applied to the ex-vivo cornea A-scan image…
View article: Imaging Chemical Kinetics of Radical Polymerization with an Ultrafast Coherent Raman Microscope
Imaging Chemical Kinetics of Radical Polymerization with an Ultrafast Coherent Raman Microscope Open
Numerous mechanisms have been proposed for polymerization to provide qualitative and quantitative prediction of how monomers spatially and temporally arrange into the polymeric chains. However, less is known about this process at the molec…
View article: Selective retina therapy monitoring by speckle variance optical coherence tomography for dosimetry control
Selective retina therapy monitoring by speckle variance optical coherence tomography for dosimetry control Open
We found a reliable correlation between the svOCT peak values and the degree of retinal lesion formation, which can be used for selecting proper laser energy during SRT.
View article: Demonstration of Optical Coherence Tomography Guided Big Bubble Technique for Deep Anterior Lamellar Keratoplasty (DALK)
Demonstration of Optical Coherence Tomography Guided Big Bubble Technique for Deep Anterior Lamellar Keratoplasty (DALK) Open
Deep anterior lamellar keratoplasty (DALK) is a highly challenging procedure for cornea transplant that involves removing the corneal layers above Descemet’s membrane (DM). This is achieved by a “big bubble” technique where a needle is ins…
View article: Analysis and evaluation of BC-mode OCT image visualization for microsurgery guidance
Analysis and evaluation of BC-mode OCT image visualization for microsurgery guidance Open
Optical coherence tomography (OCT) has been gaining acceptance in image-guided microsurgery as a noninvasive imaging technique. However, when using B-mode OCT imaging, it is difficult to continuously keep the surgical tool in the imaging f…
View article: Intraoperative Speckle Variance Optical Coherence Tomography for Tissue Temperature Monitoring During Cutaneous Laser Therapy
Intraoperative Speckle Variance Optical Coherence Tomography for Tissue Temperature Monitoring During Cutaneous Laser Therapy Open
Background: Tissue temperature monitoring during cutaneous laser therapy can lead to safer and more effective treatments. In this study, we investigate the use of speckle variance optical coherence tomography (svOCT) to monitor real-time t…