Shouqiang Zhu
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View article: TERT activator compound alleviates cigarette smoke-induced cognitive deficits by modulating hippocampal inflammation and neurogenesis: A comprehensive study integrating Mendelian randomization
TERT activator compound alleviates cigarette smoke-induced cognitive deficits by modulating hippocampal inflammation and neurogenesis: A comprehensive study integrating Mendelian randomization Open
Cigarette smoking represents a major public health concern, yet its relationship with cognitive function remains controversial. Here, we integrated two-sample Mendelian randomization (MR) with an in vivo model to interrogate this relations…
View article: Effects of etomidate versus propofol for total intravenous anaesthesia on postoperative quality of recovery in patients undergoing day-case laparoscopic cholecystectomy: protocol for a multicentre, randomised controlled non-inferiority trial
Effects of etomidate versus propofol for total intravenous anaesthesia on postoperative quality of recovery in patients undergoing day-case laparoscopic cholecystectomy: protocol for a multicentre, randomised controlled non-inferiority trial Open
Background The choice of anaesthetic agents may influence specific aspects of postoperative recovery, such as haemodynamic stability, recovery times and the incidence of adverse events, in patients undergoing day-case laparoscopic cholecys…
View article: A Genome-wide study on the genetic and causal effects of smoking in neurodegeneration
A Genome-wide study on the genetic and causal effects of smoking in neurodegeneration Open
This study identified significant genetic associations between smoking behaviors and neurodegenerative diseases. CigDay and SmkInit increased AD risk, while SmkCes was linked to reduced risks of PD and ALS.
View article: Temporal patterns of cognitive decline after hypertension onset among middle-aged and older adults in China
Temporal patterns of cognitive decline after hypertension onset among middle-aged and older adults in China Open
View article: Epidemiological Trends and Socioeconomic Inequalities in Four Major Neurological Disorders: A Global Burden of Disease Study with Bayesian Projections to 2030
Epidemiological Trends and Socioeconomic Inequalities in Four Major Neurological Disorders: A Global Burden of Disease Study with Bayesian Projections to 2030 Open
View article: Epidemiological Trends and Socioeconomic Inequalities in Four Major Neurological Disorders: A Global Burden of Disease Study with Bayesian Projections to 2030
Epidemiological Trends and Socioeconomic Inequalities in Four Major Neurological Disorders: A Global Burden of Disease Study with Bayesian Projections to 2030 Open
View article: Brain network connectivity and dementia risk: a bidirectional Mendelian randomisation perspective
Brain network connectivity and dementia risk: a bidirectional Mendelian randomisation perspective Open
Our findings identify functional networks whose connectivity patterns may be associated with dementia risk and could provide potential insights for biomarker discovery or preventive research. However, these results are based on statistical…
View article: Changes in early postoperative outcomes and complications observed in a single center during the 2022 COVID-19 pandemic wave in China: A single-center ambispective cohort study
Changes in early postoperative outcomes and complications observed in a single center during the 2022 COVID-19 pandemic wave in China: A single-center ambispective cohort study Open
Background: Currently, the effect of the 2022 nationwide coronavirus disease 2019 (COVID-19) wave on the perioperative prognosis of surgical patients in China is unclear. Thus, we aimed to explore its influence on postoperative morbidity a…
View article: Association between marital status and all-cause mortality of patients with metastatic breast cancer: a population-based study
Association between marital status and all-cause mortality of patients with metastatic breast cancer: a population-based study Open
View article: Longitudinal hemoglobin trajectories and acute kidney injury in patients undergoing cardiac surgery: a retrospective cohort study
Longitudinal hemoglobin trajectories and acute kidney injury in patients undergoing cardiac surgery: a retrospective cohort study Open
Object The purpose of this study was to describe the longitudinal dynamic hemoglobin trajectories in patients undergoing cardiac surgery and to explore whether they provide a broader perspective in predicting AKI compared to traditional th…
View article: Visceral obesity is associated with incisional hernia in patients undergoing single-port laparoscopic gynecologic surgery
Visceral obesity is associated with incisional hernia in patients undergoing single-port laparoscopic gynecologic surgery Open
View article: Association of marital status and all-cause mortality of metastatic breast cancer patients: A population-based study
Association of marital status and all-cause mortality of metastatic breast cancer patients: A population-based study Open
The authors have requested that this preprint be removed from Research Square.
View article: Neuroprotective effect of remote ischemic preconditioning in patients undergoing cardiac surgery: A randomized controlled trial
Neuroprotective effect of remote ischemic preconditioning in patients undergoing cardiac surgery: A randomized controlled trial Open
Background The neuroprotective effect of remote ischemic preconditioning (RIPC) in patients undergoing elective cardiopulmonary bypass (CPB)-assisted coronary artery bypass graft (CABG) or valvular cardiac surgery remains unclear. Methods …