Shreya Mukherjee
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View article: Exploring target selectivity in designing and identifying PI3Kα inhibitors for triple negative breast cancer with fragment-based and bioisosteric replacement approach
Exploring target selectivity in designing and identifying PI3Kα inhibitors for triple negative breast cancer with fragment-based and bioisosteric replacement approach Open
Triple-negative breast cancer (TNBC) is one of the most fatal malignancies in the world, accounting for 42% of all deaths due to metastasis. The significant development is hindered by the multi-drug resistance and poor patient compliance. …
View article: A Mechanistic Discussion on Oxidative Stress and Ferroptosis
A Mechanistic Discussion on Oxidative Stress and Ferroptosis Open
Ferroptosis is a recent form of non-apoptotic cell death, which occurs due to imbalance of iron homeostasis (iron overload). Oxidative stress due to the impairment of the antioxidant system is a major pathophysiology during ferroptosis, wh…
View article: Duration of partial melting in the lower crust of the Limpopo collisional belt
Duration of partial melting in the lower crust of the Limpopo collisional belt Open
In convergent settings, the duration of partial melting in the lower continental crust dictates how lateral shortening is accommodated by the colliding plates. Here we use the example of the ca. 2700 Ma Southern Marginal Zone of the Limpop…
View article: Using a Three-Dimensional Superimposition Technique, Studying the Effects of Different Cooling Procedures on the Adaptability of Rapidly Heat-Cured Acrylic Denture Bases
Using a Three-Dimensional Superimposition Technique, Studying the Effects of Different Cooling Procedures on the Adaptability of Rapidly Heat-Cured Acrylic Denture Bases Open
Aim: The purpose of this study is to use a 3D superimposition technique to examine how different cooling techniques affect denture base adaptation of rapidly heated acrylic resin. Setting and Design: Comparative in vitro study. Materials a…
View article: Perspective Chapter: Trauma from Occlusion – Practical Management Guidelines
Perspective Chapter: Trauma from Occlusion – Practical Management Guidelines Open
Occlusal trauma is trauma to the periodontium from functional or parafunctional force’s causing damage to the teeth and its attachment apparatus by exceeding its adaptive and reparative capacities. Occlusal instability is a common cause fo…
View article: Modelling petrogenesis of Meso- and Neoarchean andesitic rocks: an example from Singhbhum craton, India 
Modelling petrogenesis of Meso- and Neoarchean andesitic rocks: an example from Singhbhum craton, India  Open
<p>Petrogenetic processes of the Archean (>2500 Ma) andesitic rocks are strongly debated because of their distinct geochemical similarities to the modern subduction zone andesites contrast with sparse evidence for Archean lithosph…
View article: Improving the precision of garnet Sm-Nd ages using aqua regia leachate analyses
Improving the precision of garnet Sm-Nd ages using aqua regia leachate analyses Open
<p>Garnet chronology, with Sm-Nd and Lu-Hf isotope systems, can yield precise dates of metamorphic and tectonic events which can be directly linked to specific pressure-temperature conditions during its growth. Presence of inclusions…
View article: Crystallographic evaluation of low cycle fatigue crack growth in a polycrystalline Ni based superalloy
Crystallographic evaluation of low cycle fatigue crack growth in a polycrystalline Ni based superalloy Open
The present work discusses the micro-mechanism of low cycle fatigue (LCF) crack growth in smooth bar specimens of Haynes 282. Two parametric approaches, i.e. crack tip opening angle (CTOA) and maximum tangential stress (θMTS) have been opt…
View article: Arsenic induced patterns of auto-grooming response over time in Macrobrachium lamarrei: a study on behavioural plasticity
Arsenic induced patterns of auto-grooming response over time in Macrobrachium lamarrei: a study on behavioural plasticity Open
Behavioural toxicity is a very applicable area in the vast field of ecotoxicology where,assessment of the alteration of behaviour is an effective tool to evaluate neural activity in an organism. In our present study, we have shown that ars…
View article: Structural Diversities in Heterometallic Mn–Ca Cluster Chemistry from the Use of Salicylhydroxamic Acid: {Mn<sup>III</sup><sub>4</sub>Ca<sub>2</sub>}, {Mn<sup>II/III</sup><sub>6</sub>Ca<sub>2</sub>}, {Mn<sup>III/IV</sup><sub>8</sub>Ca}, and {Mn<sup>III</sup><sub>8</sub>Ca<sub>2</sub>} Complexes with Relevance to Both High- and Low-Valent States of the Oxygen-Evolving Complex
Structural Diversities in Heterometallic Mn–Ca Cluster Chemistry from the Use of Salicylhydroxamic Acid: {Mn<sup>III</sup><sub>4</sub>Ca<sub>2</sub>}, {Mn<sup>II/III</sup><sub>6</sub>Ca<sub>2</sub>}, {Mn<sup>III/IV</sup><sub>8</sub>Ca}, and {Mn<sup>III</sup><sub>8</sub>Ca<sub>2</sub>} Complexes with Relevance to Both High- and Low-Valent States of the Oxygen-Evolving Complex Open
One-pot reactions between the [Mn3O(O2CPh)6(py)x]+/0 triangular precursors and either CaBr2·xH2O or CaCl2·6H2O, in the presence of salicylhydroxamic acid (shaH2), have afforded the heterometallic complexes [MnIII4Ca2(O2CPh)4(shi)4(H2O)3(Me…
View article: CCDC 1559579: Experimental Crystal Structure Determination
CCDC 1559579: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1559957: Experimental Crystal Structure Determination
CCDC 1559957: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1559399: Experimental Crystal Structure Determination
CCDC 1559399: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1559398: Experimental Crystal Structure Determination
CCDC 1559398: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …