Siddharth Reddy
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View article: Deep learning-based precision phenotyping of spine curvature identifies novel genetic risk loci for scoliosis in the UK Biobank
Deep learning-based precision phenotyping of spine curvature identifies novel genetic risk loci for scoliosis in the UK Biobank Open
Scoliosis is the most common developmental spinal deformity, but its genetic underpinnings remain only partially understood. To enhance the identification of scoliosis-related loci, we utilized whole body dual energy X-ray absorptiometry (…
View article: Green Innovation in GTR Membranes: Combining Astaxanthin, <i>Aloe vera</i> and Chitosan for Periodontal Therapy- An <i>In Vitro</i> Study
Green Innovation in GTR Membranes: Combining Astaxanthin, <i>Aloe vera</i> and Chitosan for Periodontal Therapy- An <i>In Vitro</i> Study Open
Background: Periodontitis leads to tissue deterioration, prompting the need for effective regenerative therapies. Conventional barrier membranes, face challenges in mechanical strength and support. This study explores a novel formulation c…
View article: A double-blind, randomised phase III clinical trial to evaluate safety, immunogenicity, non-inferiority & lot to lot consistency of single component oral cholera vaccine BBV131 (Hillchol®) in comparison to Shanchol™
A double-blind, randomised phase III clinical trial to evaluate safety, immunogenicity, non-inferiority & lot to lot consistency of single component oral cholera vaccine BBV131 (Hillchol®) in comparison to Shanchol™ Open
CTRI/2022/01/039734.
View article: Effect of Ash, Crude Protein and Nitrogen in Traditional Varieties of Rice Against Sitophilus oryzae (L.) Infestation in Storage
Effect of Ash, Crude Protein and Nitrogen in Traditional Varieties of Rice Against Sitophilus oryzae (L.) Infestation in Storage Open
The management of rice weevil infestations in traditional rice varieties presents unique challenges. Traditional storage practices and methods may not always align with contemporary insect pest management strategies furthermore, the geneti…
View article: Seasonal Incidence of Major Insect Pests in Relation to Abiotic Factors in Mustard
Seasonal Incidence of Major Insect Pests in Relation to Abiotic Factors in Mustard Open
Aim: The present study was under taken to the know the incidence of major insect- pests of mustard and their correlation with abiotic factors. Study Design: Randomized Block Design (one factor anova). Place and Duration of Study: Regional …
View article: First Contact: Unsupervised Human-Machine Co-Adaptation via Mutual Information Maximization
First Contact: Unsupervised Human-Machine Co-Adaptation via Mutual Information Maximization Open
How can we train an assistive human-machine interface (e.g., an electromyography-based limb prosthesis) to translate a user's raw command signals into the actions of a robot or computer when there is no prior mapping, we cannot ask the use…
View article: ASHA: Assistive Teleoperation via Human-in-the-Loop Reinforcement Learning
ASHA: Assistive Teleoperation via Human-in-the-Loop Reinforcement Learning Open
Building assistive interfaces for controlling robots through arbitrary, high-dimensional, noisy inputs (e.g., webcam images of eye gaze) can be challenging, especially when it involves inferring the user's desired action in the absence of …
View article: Persistence of immunity and impact of a third (booster) dose of an inactivated SARS-CoV-2 vaccine, BBV152; a phase 2, double-blind, randomised controlled trial
Persistence of immunity and impact of a third (booster) dose of an inactivated SARS-CoV-2 vaccine, BBV152; a phase 2, double-blind, randomised controlled trial Open
Background Neutralising antibody responses to SARS-CoV-2 vaccines have been reported to decline within 6 months of vaccination, particularly against Variants of Concern (VOC). We assessed the immunogenicity and safety of a booster dose of …
View article: Immunogenicity and safety of an inactivated SARS-CoV-2 vaccine (BBV152) in children from 2 to 18 years of age: an open-label, age-de-escalation phase 2/3 study
Immunogenicity and safety of an inactivated SARS-CoV-2 vaccine (BBV152) in children from 2 to 18 years of age: an open-label, age-de-escalation phase 2/3 study Open
Background We assessed the safety, reactogenicity, and immunogenicity of BBV152 in an open-label age de-escalation study in three age cohorts of children from 18 years of age down to 2 years of age. Methods This was a phase 2/3 open-label,…
View article: Persisting antibody responses to Vi polysaccharide–tetanus toxoid conjugate (Typbar TCV®) vaccine up to 7 years following primary vaccination of children < 2 years of age with, or without, a booster vaccination
Persisting antibody responses to Vi polysaccharide–tetanus toxoid conjugate (Typbar TCV®) vaccine up to 7 years following primary vaccination of children < 2 years of age with, or without, a booster vaccination Open
To extend protection, administering a booster of Typbar TCV® to children ∼5 years after their primary dose, i.e., coinciding with school entry, may be advisable. Typbar TCV® is presently the only WHO pre-qualified Vi conjugate vaccine with…
View article: A multi-centre, post-marketing surveillance study of Vi polysaccharide–tetanus toxoid conjugate vaccine (Typbar TCV®) in India
A multi-centre, post-marketing surveillance study of Vi polysaccharide–tetanus toxoid conjugate vaccine (Typbar TCV®) in India Open
A typhoid Vi capsular-polysaccharide tetanus toxoid conjugate vaccine (Typbar-TCV®) was recommended by the World Health Organization for use in children >6 months of age. The present post-marketing surveillance study was intended to assess…
View article: Safety and immunogenicity clinical trial of an inactivated SARS-CoV-2 vaccine, BBV152 (a phase 2, double-blind, randomised controlled trial) and the persistence of immune responses from a phase 1 follow-up report
Safety and immunogenicity clinical trial of an inactivated SARS-CoV-2 vaccine, BBV152 (a phase 2, double-blind, randomised controlled trial) and the persistence of immune responses from a phase 1 follow-up report Open
Background BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine (3 µg or 6 µg) formulated with a Toll-like receptor 7/8 agonist molecule adsorbed to alum (Algel-IMDG). Earlier, we reported findings from a phase 1 (vaccination regimen on…
View article: Safety and immunogenicity trial of an inactivated SARS-CoV-2 vaccine-BBV152: a phase 1, double-blind, randomised control trial
Safety and immunogenicity trial of an inactivated SARS-CoV-2 vaccine-BBV152: a phase 1, double-blind, randomised control trial Open
Background: BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine formulated with a TLR 7/8 agonist molecule adsorbed to alum (Algel-IMDG). Methods We conducted a double-blind randomized controlled phase 1 clinical trial to evaluate the …
View article: Mid-term outcomes of arthroscopic osteochondral autograft transplantation for focal chondral defects of the knee
Mid-term outcomes of arthroscopic osteochondral autograft transplantation for focal chondral defects of the knee Open
Objectives: Osteochondral autograft transplantation (OAT) for the management of cartilage defect involves direct transfer of hyaline cartilage to the defect site. The study aims to assess mid-term functional outcomes of arthroscopic treatm…
View article: Where Do You Think You're Going?: Inferring Beliefs about Dynamics from\n Behavior
Where Do You Think You're Going?: Inferring Beliefs about Dynamics from\n Behavior Open
Inferring intent from observed behavior has been studied extensively within\nthe frameworks of Bayesian inverse planning and inverse reinforcement learning.\nThese methods infer a goal or reward function that best explains the actions of\n…
View article: Assessment of newborn care corners in selected public health facilities in Bihar
Assessment of newborn care corners in selected public health facilities in Bihar Open
The network of NBCCs needs to be strengthened across the state and linked with higher facilities to achieve the desired reduction in neonatal morbidity and mortality.
View article: Rollout of quality assurance interventions in labor room in two districts of Bihar, India
Rollout of quality assurance interventions in labor room in two districts of Bihar, India Open
It is possible to have an implementable quality assurance mechanism within public health system with sustained efforts and commitment.
View article: An assessment of bicycle intervention to improve service delivery by accredited social health activists in selected blocks of West Champaran district of Bihar
An assessment of bicycle intervention to improve service delivery by accredited social health activists in selected blocks of West Champaran district of Bihar Open
The intervention demonstrated the potential of ASHAs to improve their functioning at the grass-root level. The scale-up of bicycle intervention should be supplemented with reforms in financial incentives disbursement and better system supp…