Shuang Hou
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View article: Fusobacterium nucleatum drives gastric cancer metastasis via Gbp-CypA-NF-κB-mediated CXCL8 crosstalk between tumor cells and mast cells
Fusobacterium nucleatum drives gastric cancer metastasis via Gbp-CypA-NF-κB-mediated CXCL8 crosstalk between tumor cells and mast cells Open
In summary, this study suggests that Fn contributes to GC progression by promoting tumor cell migration, MCs recruitment and activation. Simultaneously, the enhanced CXCL8-mediated crosstalk between GC cells and MCs plays a vital role in t…
View article: A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate
A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate Open
Glutarate is a platform chemical with diversified applications. It is also an endogenous metabolite involved in various physiological processes. Deficiency in glutaryl‐CoA dehydrogenase (GcdH) for glutarate catabolism induces the inherited…
View article: A genetically encoded biosensor for point-of-care and live-cell detection of d-2-hydroxyglutarate
A genetically encoded biosensor for point-of-care and live-cell detection of d-2-hydroxyglutarate Open
View article: Fluorescence imaging assisted precise assessment of the depth of myometrial invasion in endometrial cancer lesions
Fluorescence imaging assisted precise assessment of the depth of myometrial invasion in endometrial cancer lesions Open
View article: Enhancement of YTHDF2 plays a protective role in acute IRI models through downregulation of TUG1 expression
Enhancement of YTHDF2 plays a protective role in acute IRI models through downregulation of TUG1 expression Open
As one of the major causes of acute kidney injury, renal ischemia-reperfusion is a common health problem in a series of clinical situations, including renal transplantation. Although the mechanisms of renal IRI have been widely investigate…
View article: eIF6: a promising therapeutic target for gastric carcinoma via PI3K/AKT pathway modulation
eIF6: a promising therapeutic target for gastric carcinoma via PI3K/AKT pathway modulation Open
eIF6's overexpression in GC suggests its role in tumor progression, highlighting its potential as a therapeutic target. The study provides a foundation for developing targeted therapies against eIF6 and emphasizes the need for further rese…
View article: Termination-acidity tailoring of molybdenum carbides for alkaline hydrogen evolution reaction
Termination-acidity tailoring of molybdenum carbides for alkaline hydrogen evolution reaction Open
View article: Vibration characteristics and active control strategy of hybrid vehicle dual-motor electric drive system under transient impact conditions
Vibration characteristics and active control strategy of hybrid vehicle dual-motor electric drive system under transient impact conditions Open
View article: A case report of an M protein-negative patient with POEMS syndrome associated with renal involvement
A case report of an M protein-negative patient with POEMS syndrome associated with renal involvement Open
View article: Comparative ultrastructural and transcriptomic profile analysis of skin tissues from indigenous, improved meat, and dairy goat breeds
Comparative ultrastructural and transcriptomic profile analysis of skin tissues from indigenous, improved meat, and dairy goat breeds Open
View article: An Ultrasensitive Biosensor for Probing Subcellular Distribution and Mitochondrial Transport of <scp>l</scp>‐2‐Hydroxyglutarate
An Ultrasensitive Biosensor for Probing Subcellular Distribution and Mitochondrial Transport of <span>l</span>‐2‐Hydroxyglutarate Open
l ‐2‐Hydroxyglutarate ( l ‐2‐HG) is a functionally compartmentalized metabolite involved in various physiological processes. However, its subcellular distribution and mitochondrial transport remain unclear owing to technical limitations. I…
View article: Comparative skin ultrastructure and transcriptome analysis of indigenous, improved meat goats, and dairy goats breeds identified key genes and potential molecular mechanisms affecting goatskin quality
Comparative skin ultrastructure and transcriptome analysis of indigenous, improved meat goats, and dairy goats breeds identified key genes and potential molecular mechanisms affecting goatskin quality Open
Background High-quality goatskins are valuable byproducts usually produced by indigenous goat breeds with poorer production performance in Asia and Africa. However, the genetic and molecular mechanisms underpinning goatskin's biomechanical…
View article: Vibration characteristics and active control strategy of hybrid vehicle dual-motor electric drive system under transient impact conditions
Vibration characteristics and active control strategy of hybrid vehicle dual-motor electric drive system under transient impact conditions Open
View article: Comprehensive Analysis Identifies PKP3 Overexpression in Pancreatic Cancer Related to Unfavorable Prognosis
Comprehensive Analysis Identifies PKP3 Overexpression in Pancreatic Cancer Related to Unfavorable Prognosis Open
Plakophilin 3 (PKP3) affects cell signal transduction and cell adhesion and performs a crucial function in tumorigenesis. The current investigation evaluated the predictive significance and underlying processes of PKP3 within pancreatic ca…
View article: Metallic W/WO2 solid-acid catalyst boosts hydrogen evolution reaction in alkaline electrolyte
Metallic W/WO2 solid-acid catalyst boosts hydrogen evolution reaction in alkaline electrolyte Open
The lack of available protons severely lowers the activity of alkaline hydrogen evolution reaction process than that in acids, which can be efficiently accelerated by tuning the coverage and chemical environment of protons on catalyst surf…
View article: Image inpainting via progressive decoder and gradient guidance
Image inpainting via progressive decoder and gradient guidance Open
Very recently, with the widespread research of deep learning, its achievements are increasingly evident in image inpainting tasks. However, many existing multi-stage methods fail to effectively inpainting the larger missing areas, their co…
View article: Electromechanical Coupling Dynamic Characteristics of the Dual-Motor Electric Drive System of Hybrid Electric Vehicles
Electromechanical Coupling Dynamic Characteristics of the Dual-Motor Electric Drive System of Hybrid Electric Vehicles Open
The electric mode is the main operational mode of dual-motor hybrid electric vehicles (HEVs), so the reliability of the dual-motor electric drive system (DEDS) is particularly important. To research the electromechanical coupling mechanism…
View article: Data from A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens
Data from A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens Open
The clinical practice of oncology is being transformed by molecular diagnostics that will enable predictive and personalized medicine. Current technologies for quantitation of the cancer proteome are either qualitative (e.g., immunohistoch…
View article: Supplementary Methods, Figures 1-14 from A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens
Supplementary Methods, Figures 1-14 from A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens Open
Supplementary Methods, Figures 1-14 from A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens
View article: Supplementary Methods, Figures 1-14 from A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens
Supplementary Methods, Figures 1-14 from A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens Open
Supplementary Methods, Figures 1-14 from A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens
View article: Data from A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens
Data from A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens Open
The clinical practice of oncology is being transformed by molecular diagnostics that will enable predictive and personalized medicine. Current technologies for quantitation of the cancer proteome are either qualitative (e.g., immunohistoch…
View article: Inpainting larger missing regions via progressive guidance decoding network
Inpainting larger missing regions via progressive guidance decoding network Open
For images corrupted for various reasons, the size of the corrupted area is often arbitrary and it has been a challenge to inpainting the larger missing areas. Though popular multistage networks ease the inpainting difficulty by repairing …
View article: A Novel Cuproptosis‐Associated Gene Signature to Predict Prognosis in Patients with Pancreatic Cancer
A Novel Cuproptosis‐Associated Gene Signature to Predict Prognosis in Patients with Pancreatic Cancer Open
Background . Pancreatic cancer (PAAD) is a malignant tumor with a poor prognosis and lacks sensitive biomarkers for diagnosis and targeted therapy. Cuproptosis, a recently proposed form of cell death based on cellular copper ion concentrat…
View article: Effect of different top electrodes on dielectric properties of Pb<sub>0.3</sub>Sr<sub>0.7</sub>TiO<sub>3</sub>thin film
Effect of different top electrodes on dielectric properties of Pb<sub>0.3</sub>Sr<sub>0.7</sub>TiO<sub>3</sub>thin film Open
The PST thin films with different top electrodes were prepared by magnetron sputtering and Sol-gel, respectively. The effects of different top electrodes on Dielectric and Tunable Properties of the films were studied. It is found that the …
View article: Metallic W/WO2 solid-acid catalyst boosts hydrogen evolution reaction in alkaline electrolyte
Metallic W/WO2 solid-acid catalyst boosts hydrogen evolution reaction in alkaline electrolyte Open
The lack of available protons severely lowers the activity of alkaline hydrogen evolution reaction (HER) process than that in acids, which can be efficiently accelerated by tuning the coverage and chemical environment of protons on catalys…
View article: The design strategy and implementation method of Ga-based material in the anode of advanced lithium-ion battery: A mini review
The design strategy and implementation method of Ga-based material in the anode of advanced lithium-ion battery: A mini review Open
In modern society, there is an increasing demand for energy storage solutions with superior energy density. Due to the low capacity of commercial graphite anode (372 mAh/g), high capacity and high stability anode materials for lithium-ion …
View article: A Selective Fluorescent l-Lactate Biosensor Based on an l-Lactate-Specific Transcription Regulator and Förster Resonance Energy Transfer
A Selective Fluorescent l-Lactate Biosensor Based on an l-Lactate-Specific Transcription Regulator and Förster Resonance Energy Transfer Open
Selective detection of l-lactate levels in foods, clinical, and bacterial fermentation samples has drawn intensive attention. Many fluorescent biosensors based on non-stereoselective recognition elements have been developed for lactate det…
View article: Evaluation of poly(N-isopropylacrylamide)/tetraphenylethylene/amphotericin B-based visualized antimicrobial nanofiber wound dressing for whole skin wound healing in rats
Evaluation of poly(N-isopropylacrylamide)/tetraphenylethylene/amphotericin B-based visualized antimicrobial nanofiber wound dressing for whole skin wound healing in rats Open
View article: The role of Kimmelstiel-Wilson nodule in the kidney outcome in patients with diabetic kidney disease: A two-center retrospective cohort study
The role of Kimmelstiel-Wilson nodule in the kidney outcome in patients with diabetic kidney disease: A two-center retrospective cohort study Open
In T2DM patients with DKD, the K-W nodule was associated with a more severe phenotype, and to some extent, associated with poorer renal outcome, but might not be an independent risk factor for the progression of ESKD.
View article: Development of a High-Throughput Screening Analysis for 195 Pesticides in Raw Milk by Modified QuEChERS Sample Preparation and Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry
Development of a High-Throughput Screening Analysis for 195 Pesticides in Raw Milk by Modified QuEChERS Sample Preparation and Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry Open
This study aimed to develop a simple, high-throughput method based on modified QuEChERS (quick, easy, cheap, effective, rugged, and safe) followed by liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q-TOF/MS) for the r…