Kun Chen
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View article: DAWP: A framework for global observation forecasting via Data Assimilation and Weather Prediction in satellite observation space
DAWP: A framework for global observation forecasting via Data Assimilation and Weather Prediction in satellite observation space Open
Weather prediction is a critical task for human society, where impressive progress has been made by training artificial intelligence weather prediction (AIWP) methods with reanalysis data. However, reliance on reanalysis data limits the AI…
View article: Screening and Risk Algorithms for Detecting Pediatric Suicide Risk in the Emergency Department
Screening and Risk Algorithms for Detecting Pediatric Suicide Risk in the Emergency Department Open
Importance The Joint Commission requires hospitals and behavioral health care organizations to identify patients at risk of suicide (National Patient Safety Goal 15.01.01). Risk algorithms and in-person screening for suicide risk show util…
View article: A Mortality Prediction Nomogram for Stenotrophomonas maltophilia Bloodstream Infection
A Mortality Prediction Nomogram for Stenotrophomonas maltophilia Bloodstream Infection Open
Septic shock and respiratory diseases were independent risk factors for mortality in patients with S. maltophilia BSIs. The nomogram model developed in this study showed good predictive value for the survival rates of patients with …
View article: Unraveling Epilepsy Biomarkers through Single-Cell Sequencing and GEO Data Integration: A Focus on Parthanatos Pathway
Unraveling Epilepsy Biomarkers through Single-Cell Sequencing and GEO Data Integration: A Focus on Parthanatos Pathway Open
Background: Epilepsy is a chronic brain disorder with complex molecular mechanisms. Parthanatos, a PARP-1-dependent programmed cell death pathway, has been implicated in neurodegenerative diseases and mitochondrial dysfunction, which are c…
View article: High-fat and low-fiber diet elevates the gut resistome: a comparative metagenomic study
High-fat and low-fiber diet elevates the gut resistome: a comparative metagenomic study Open
Antimicrobial resistance (AMR) is a global health challenge. The gut microbiome, a major reservoir for AMR, is influenced by dietary habits. However, the specific impact of dietary patterns on gut resistome remains poorly understood. This …
View article: Sex differences in the peripheral blood transcriptome and their associations with neuroimaging and cognition in schizophrenia
Sex differences in the peripheral blood transcriptome and their associations with neuroimaging and cognition in schizophrenia Open
Our results demonstrate that, males and females with SCZ exhibit distinct degrees of peripheral blood transcriptomic dysregulation and distinct correlations between peripheral blood transcriptome and functional neuroimage. These sex-specif…
View article: Combining spectral and texture indexes predicts plant diversity in temperate riverine wetlands of the lower Yellow River, China
Combining spectral and texture indexes predicts plant diversity in temperate riverine wetlands of the lower Yellow River, China Open
Remote sensing technology offers a cost-effective and efficient solution for the large-scale monitoring of wetland plant diversity. This study introduces a methodological framework that integrates spectral and texture indexes for predictin…
View article: CRISPR-Cas9 screening identifies a gene signature predictive of prognosis in glioblastoma
CRISPR-Cas9 screening identifies a gene signature predictive of prognosis in glioblastoma Open
Glioblastoma (GBM) is the most aggressive primary brain malignancy, characterized by a poor prognosis and limited therapeutic options. Identifying essential genes and pathways involved in GBM proliferation is important for developing progn…
View article: Feasibility and importance of universal suicide screening in a pediatric emergency department
Feasibility and importance of universal suicide screening in a pediatric emergency department Open
Suicide is a leading cause of death in the United States. In 2018, the Joint Commission recommended screening patients for suicide risk in healthcare settings. Universal screening may increase the safety of at-risk youth, but is challengin…
View article: Model Predicting Positive Aspects of Caregiving Among Family Cares of Persons With Dementia: A Longitudinal Cohort Study
Model Predicting Positive Aspects of Caregiving Among Family Cares of Persons With Dementia: A Longitudinal Cohort Study Open
Aim Positive aspects of caregiving among family carers of persons living with dementia not only benefit the carers' health, but also enhance the quality and sustainability of invaluable informal care resources. To better inform the develop…
View article: Align-DA: Align Score-based Atmospheric Data Assimilation with Multiple Preferences
Align-DA: Align Score-based Atmospheric Data Assimilation with Multiple Preferences Open
Data assimilation (DA) aims to estimate the full state of a dynamical system by combining partial and noisy observations with a prior model forecast, commonly referred to as the background. In atmospheric applications, this problem is fund…
View article: Molecular and clinical insights into HIV-associated and HIV-negative aggressive B-cell lymphomas: prognostic quantitative biomarker analysis and therapeutic implications
Molecular and clinical insights into HIV-associated and HIV-negative aggressive B-cell lymphomas: prognostic quantitative biomarker analysis and therapeutic implications Open
Background HIV-associated lymphomas (HALs) exhibit aggressive features and poorer prognosis compared to HIV-negative lymphomas. However, their molecular and clinicopathological characteristics remain unclear in the antiretroviral therapy (…
View article: Symptomatic central nervous system infections in kidney transplant recipients: a 20-years multicenter observational study
Symptomatic central nervous system infections in kidney transplant recipients: a 20-years multicenter observational study Open
View article: Identifying patients at risk of suicide using data from health information exchanges
Identifying patients at risk of suicide using data from health information exchanges Open
View article: Gamification as an Innovative Approach for the Assessment of Procedural Knowledge
Gamification as an Innovative Approach for the Assessment of Procedural Knowledge Open
In the era of artificial intelligence (AI), generative AI tools like ChatGPT 4.5 have greatly improved the ease of obtaining answers to questions, thereby diminishing the importance of memorizing declarative knowledge while increasing the …
View article: A Fault Sources-Based Probabilistic Seismic Hazard Analysis for Next-Generation Seismic Ground Motion Parameters Zonation Map of China
A Fault Sources-Based Probabilistic Seismic Hazard Analysis for Next-Generation Seismic Ground Motion Parameters Zonation Map of China Open
The probabilistic seismic hazard analysis (PSHA) method used in existing seismic ground motion parameters zonation map of China (the traditional PSHA-CN method) is based on a two-dimensional area seismic source framework and does not accou…
View article: Post-discharge suicide prediction among US veterans using natural language processing-enriched social and behavioral determinants of health
Post-discharge suicide prediction among US veterans using natural language processing-enriched social and behavioral determinants of health Open
Despite the established association between social and behavioral determinants of health (SBDH) and suicide risk, SBDHs from unstructured electronic health record notes for suicide prediction remain underutilized. This study investigates t…
View article: Satellite Observations Guided Diffusion Model for Accurate Meteorological States at Arbitrary Resolution
Satellite Observations Guided Diffusion Model for Accurate Meteorological States at Arbitrary Resolution Open
Accurate acquisition of surface meteorological conditions at arbitrary locations holds significant importance for weather forecasting and climate simulation. Due to the fact that meteorological states derived from satellite observations ar…
View article: Salvaging Forbidden Treasure in Medical Data: Utilizing Surrogate Outcomes and Single Records for Rare Event Modeling
Salvaging Forbidden Treasure in Medical Data: Utilizing Surrogate Outcomes and Single Records for Rare Event Modeling Open
The vast repositories of Electronic Health Records (EHR) and medical claims hold untapped potential for studying rare but critical events, such as suicide attempt. Conventional setups often model suicide attempt as a univariate outcome and…
View article: Code Readability in the Age of Large Language Models: An Industrial Case Study from Atlassian
Code Readability in the Age of Large Language Models: An Industrial Case Study from Atlassian Open
Software engineers spend a significant amount of time reading code during the software development process, especially in the age of large language models (LLMs) that can automatically generate code. However, little is known about the read…
View article: Research on the Allometric Growth Relationship and Coordination between China's New Urbanization and Electricity Consumption
Research on the Allometric Growth Relationship and Coordination between China's New Urbanization and Electricity Consumption Open
View article: Recent Progress in Preparation of Single Crystal 3C-SiC
Recent Progress in Preparation of Single Crystal 3C-SiC Open
View article: Research on the allometric growth relationship and coordination between China's new urbanization and electricity consumption
Research on the allometric growth relationship and coordination between China's new urbanization and electricity consumption Open
View article: Effects of biochar on the growth of maize in coastal salt-affected soil in the Yellow River Delta
Effects of biochar on the growth of maize in coastal salt-affected soil in the Yellow River Delta Open
Global climate change is exerting profound impacts on coastal ecosystems in the Yellow River Delta, leading to significant degradation, with plant growth constrained by dual stressors of saltwater intrusion and declining nutrient supply. T…
View article: Enhanced antibody response to the conformational non-RBD region <i>via</i> DNA prime-protein boost elicits broad cross-neutralization against SARS-CoV-2 variants
Enhanced antibody response to the conformational non-RBD region <i>via</i> DNA prime-protein boost elicits broad cross-neutralization against SARS-CoV-2 variants Open
Preventing immune escape of SARS-CoV-2 variants is crucial in vaccine development to ensure broad protection against the virus. Conformational epitopes beyond the RBD region are vital components of the spike protein but have received limit…
View article: Physics-guided neural network for predicting international roughness index on flexible pavements considering accuracy, uncertainty and stability
Physics-guided neural network for predicting international roughness index on flexible pavements considering accuracy, uncertainty and stability Open
View article: Halogen enrichment on the continental surface: a perspective from loess
Halogen enrichment on the continental surface: a perspective from loess Open
View article: The Empirical Spectral Distribution of i.i.d. Random Matrices with Random Perturbations
The Empirical Spectral Distribution of i.i.d. Random Matrices with Random Perturbations Open
A large i.i.d. random matrix with deterministic low-rank perturbation has been extensively studied, particularly in the aspects of the ESD (Empirical Spectral Distribution) and the outliers of eigenvalues. In this work, we investigate the …
View article: Multidimensional Perspectives on the Teaching and Practice of Typography Design
Multidimensional Perspectives on the Teaching and Practice of Typography Design Open
With the continuous deepening of teaching reforms in higher education, it is imperative to reform the teaching of art and design courses. Research has found that the current teaching of typography design in art and design courses has rigid…
View article: Thermal enhancement of targeted cooling thermosyphon array applied to the embankment–bridge transition section of the Qinghai–Tibet Railway in warm permafrost
Thermal enhancement of targeted cooling thermosyphon array applied to the embankment–bridge transition section of the Qinghai–Tibet Railway in warm permafrost Open
Permafrost degradation in the embankment–bridge transition section (EBTS) along the Qinghai–Tibet Railway has led to extensive damage to bridge structures, posing a serious threat to railway safety. With the ongoing global warming, reinfor…