Shuanghu Yuan
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View article: Integrated diagnostic evaluation of multiple malignant neoplasms via <sup>99m</sup> Tc‑MDP three‑phase bone imaging: A case report
Integrated diagnostic evaluation of multiple malignant neoplasms via <sup>99m</sup> Tc‑MDP three‑phase bone imaging: A case report Open
View article: BRUC：BOWEL PREPARATION, RECTAL EMPTYING, ULTRASOUND BLADDER VOLUME MONITORING AND CBCT-GUIDED PROTON THERAPY IN PROSTATE CANCER
BRUC：BOWEL PREPARATION, RECTAL EMPTYING, ULTRASOUND BLADDER VOLUME MONITORING AND CBCT-GUIDED PROTON THERAPY IN PROSTATE CANCER Open
View article: Case Report: Severe gastric atrophy associated with a novel homozygous variant in LRBA
Case Report: Severe gastric atrophy associated with a novel homozygous variant in LRBA Open
Background The prevalence of atrophic gastritis is challenging to determine, considering that it is typically asymptomatic and that its definition and diagnosis vary among studies. Furthermore, gastric atrophy is underreported and is often…
View article: SPATIALLY FRACTIONATED PROTON PENCIL-BEAM-SCANNING THERAPY (SFPT) FOR BULKY TUMORS: A PRELIMINARY CLINICAL EXPLORATION
SPATIALLY FRACTIONATED PROTON PENCIL-BEAM-SCANNING THERAPY (SFPT) FOR BULKY TUMORS: A PRELIMINARY CLINICAL EXPLORATION Open
View article: Nanosensitizer for enhanced radiotherapy via tumor microenvironment reshaping and ROS amplification
Nanosensitizer for enhanced radiotherapy via tumor microenvironment reshaping and ROS amplification Open
View article: Clinical and dosimetric risk factors for radiation pneumonitis after proton therapy in lung cancer patients: a retrospective study
Clinical and dosimetric risk factors for radiation pneumonitis after proton therapy in lung cancer patients: a retrospective study Open
Dosimetric parameters, specifically V10, V20, V30, V40, V50, V60, and MLD of the ipsilateral lung, along with V40, V50, and V60 of the total lung, are associated with grade ≥2 RP in lung cancer patients receiving proton radiotherapy. By id…
View article: Preoperative Anemia and Perioperative Outcomes in Gynecological Surgery: A Single-Center Retrospective Study
Preoperative Anemia and Perioperative Outcomes in Gynecological Surgery: A Single-Center Retrospective Study Open
Preoperative anemia was related to higher incidence of perioperative RBC transfusion and complication, and it increased hospitalization costs and prolonged LOS in gynecological inpatients. PBM before surgery could help improve perioperativ…
View article: Radiation Esophagitis in Breast Cancer Patients Undergoing Hypofractionated Regional Nodal Radiotherapy: Voxel-Based Analysis
Radiation Esophagitis in Breast Cancer Patients Undergoing Hypofractionated Regional Nodal Radiotherapy: Voxel-Based Analysis Open
View article: 644 | EFFICACY OF ZANUBRUTINIB IN NEWLY DIAGNOSED MYD88‐MUTATED DIFFUSE LARGE B‐CELL LYMPHOMA: A RETROSPECTIVE SINGLE‐CENTER REAL‐WORLD STUDY
644 | EFFICACY OF ZANUBRUTINIB IN NEWLY DIAGNOSED MYD88‐MUTATED DIFFUSE LARGE B‐CELL LYMPHOMA: A RETROSPECTIVE SINGLE‐CENTER REAL‐WORLD STUDY Open
View article: Comparison of neoadjuvant chemotherapy plus immunotherapy versus chemoradiotherapy for esophageal squamous cell carcinoma patients: efficacy and safety outcomes
Comparison of neoadjuvant chemotherapy plus immunotherapy versus chemoradiotherapy for esophageal squamous cell carcinoma patients: efficacy and safety outcomes Open
The NCRT cohort exhibited greater rates of pCR and lymph node pCR rates than the NICT cohort. Conversely, the NICT group presented with fewer postoperative complications the NCRT group.
View article: Integration of Circulating Tumor DNA and Metabolic Parameters on <sup>18</sup>F‐Fludeoxyglucose Positron Emission Tomography for Outcome Prediction in Unresectable Locally Advanced Non‐Small Cell Lung Cancer
Integration of Circulating Tumor DNA and Metabolic Parameters on <sup>18</sup>F‐Fludeoxyglucose Positron Emission Tomography for Outcome Prediction in Unresectable Locally Advanced Non‐Small Cell Lung Cancer Open
This prospective study explores the prognostic value of circulating tumor DNA (ctDNA) and positron emission tomography/computed tomograpy (PET/CT) in unresectable locally advanced non‐small cell lung cancer (LA‐NSCLC) treated with definiti…
View article: Effectiveness, safety, and patterns of use of camrelizumab in advanced esophageal cancer: an individual patient data pooled analysis of 987 patients from three prospective cohort studies
Effectiveness, safety, and patterns of use of camrelizumab in advanced esophageal cancer: an individual patient data pooled analysis of 987 patients from three prospective cohort studies Open
Background and aims This individual patient data pooled analysis aimed to evaluate the effectiveness, safety, and patterns of use of camrelizumab in a large cohort of advanced esophageal cancer (AEC) patients. Approach and results Adult pa…
View article: Impact of radiation dose to immune cells on survival in patients with esophageal cancer receiving neoadjuvant chemoradiotherapy: a retrospective analysis
Impact of radiation dose to immune cells on survival in patients with esophageal cancer receiving neoadjuvant chemoradiotherapy: a retrospective analysis Open
View article: A meta-analysis of the value of indocyanine green fluorescence imaging in guiding surgical resection of primary and metastatic liver cancer
A meta-analysis of the value of indocyanine green fluorescence imaging in guiding surgical resection of primary and metastatic liver cancer Open
Indocyanine green fluorescence imaging is a safe and effective intraoperative navigation technique that improves surgical outcomes and prognostic indicators in liver cancer resection. However, its efficacy in metastatic liver cancer surger…
View article: A Case Report of Neonatal Chronic Granulomatous Disease Co-occurring with G6PD Deficiency
A Case Report of Neonatal Chronic Granulomatous Disease Co-occurring with G6PD Deficiency Open
View article: Comparison of neoadjuvant chemoradiotherapy versus chemoradiotherapy plus immunotherapy for esophageal squamous cell carcinoma in a real-world multicenter cohort: a propensity score matching study
Comparison of neoadjuvant chemoradiotherapy versus chemoradiotherapy plus immunotherapy for esophageal squamous cell carcinoma in a real-world multicenter cohort: a propensity score matching study Open
View article: Dose-Volume Constraints Parameters for Lung Tissue in Thoracic Radiotherapy Following Immune Checkpoint Inhibitor Treatment
Dose-Volume Constraints Parameters for Lung Tissue in Thoracic Radiotherapy Following Immune Checkpoint Inhibitor Treatment Open
The recommended dose thresholds for MLD, V10, V20, V30, and V40 are lower than the current guidelines, underscoring the importance of radiotherapy planning to minimize symptomatic RP occurrence in patients receiving ICI-TRT.
View article: Proton therapy for breast cancer: Reducing toxicity
Proton therapy for breast cancer: Reducing toxicity Open
Radiotherapy is a crucial component in the holistic management of breast cancer, with approximately 60% of individuals diagnosed with breast cancer requiring this treatment. As the survival rate of individuals with breast cancer has signif…
View article: Comparison of Neoadjuvant Chemoradiotherapy versus Chemoradiotherapy Plus Immunotherapy for Esophageal Squamous Cell Carcinoma in a Real-World Multicenter Cohort: A Propensity Score Matching Study
Comparison of Neoadjuvant Chemoradiotherapy versus Chemoradiotherapy Plus Immunotherapy for Esophageal Squamous Cell Carcinoma in a Real-World Multicenter Cohort: A Propensity Score Matching Study Open
Background:Chemoradiotherapy combined with immunotherapy (NICRT) is a new neoadjuvant treatment approach that has raised concerns regarding potential challenges in surgery and postoperative complications. This study aimed to compare the ef…
View article: Radiogenomics models for predicting prognosis in locally advanced non-small cell lung cancer patients undergoing definitive chemoradiotherapy
Radiogenomics models for predicting prognosis in locally advanced non-small cell lung cancer patients undergoing definitive chemoradiotherapy Open
The radiomics model, genomics model and radiogenomics model can all predict the prognosis of dCRT for LA-NSCLC, and the radiogenomics model is superior to the single type model.
View article: Prognostic biomarker tumor-infiltrating lymphocytes failed to serve as a predictive biomarker for postoperative radiotherapy in completely resected pN2 non-small cell lung cancer: a retrospective analysis
Prognostic biomarker tumor-infiltrating lymphocytes failed to serve as a predictive biomarker for postoperative radiotherapy in completely resected pN2 non-small cell lung cancer: a retrospective analysis Open
View article: Current status and prospect of particle therapy for esophageal cancer
Current status and prospect of particle therapy for esophageal cancer Open
Esophageal cancer is among the top causes of cancer‐related mortality worldwide, and the main treatment modality for locally advanced esophageal cancer is concurrent chemoradiotherapy. The current photon‐based radiotherapy modalities and p…
View article: CT-based radiomics combined with hematologic parameters for survival prediction in locally advanced esophageal cancer patients receiving definitive chemoradiotherapy
CT-based radiomics combined with hematologic parameters for survival prediction in locally advanced esophageal cancer patients receiving definitive chemoradiotherapy Open
Objectives The purpose of this study was to investigate the prognostic significance of radiomics in conjunction with hematological parameters in relation to the overall survival (OS) of individuals diagnosed with esophageal squamous cell c…
View article: Clinical Guidelines for the Prevention and Treatment of Radiation‐induced Bladder Injury
Clinical Guidelines for the Prevention and Treatment of Radiation‐induced Bladder Injury Open
Radiation‐induced bladder injury is a common complication after pelvic radiotherapy. Few studies exist on diagnosing and treating radiation‐induced bladder injury, with no established guidelines or consensus in China or internationally. Cl…
View article: Recurrence/prognosis estimation using a molecularly positive surgical margin‐based model calls for alternative curative strategies in <scp>pIIIA</scp>/<scp>N2 NSCLC</scp>
Recurrence/prognosis estimation using a molecularly positive surgical margin‐based model calls for alternative curative strategies in <span>pIIIA</span>/<span>N2 NSCLC</span> Open
Stage pIIIA/N2 non‐small cell lung cancer (NSCLC) is primarily treated by complete surgical resection combined with neoadjuvant/adjuvant therapies. However, up to 40% of patients experience tumor recurrence. Here, we studied 119 stage pIII…
View article: Novel model integrating computed tomography-based image markers with genetic markers for discriminating radiation pneumonitis in patients with unresectable stage III non-small cell lung cancer receiving radiotherapy: a retrospective multi-center radiogenomics study
Novel model integrating computed tomography-based image markers with genetic markers for discriminating radiation pneumonitis in patients with unresectable stage III non-small cell lung cancer receiving radiotherapy: a retrospective multi-center radiogenomics study Open
View article: Multi‐omics predictive model based on clinical, radiomic and genomic features for predicting the response of limited‐stage small cell lung cancer to definitive chemoradiotherapy
Multi‐omics predictive model based on clinical, radiomic and genomic features for predicting the response of limited‐stage small cell lung cancer to definitive chemoradiotherapy Open
Dear Editor, The efficacy of definitive concurrent or sequential chemoradiotherapy (dCRT) varies significantly among limited-stage small-cell lung cancer (LS-SCLC) patients, with about 10%–13% of patients achieving 5-year survival, while 5…
View article: Combined inflammatory parameters and tertiary lymphoid structure predict prognosis in patients with resectable non-small cell lung cancer treated with neoadjuvant chemoimmunotherapy
Combined inflammatory parameters and tertiary lymphoid structure predict prognosis in patients with resectable non-small cell lung cancer treated with neoadjuvant chemoimmunotherapy Open
Introduction Neoadjuvant chemoimmunotherapy shows great potential for patients with non-small cell lung cancer (NSCLC), but no clear prognostic markers have been identified. This study investigates the correlation between inflammatory para…
View article: Tertiary lymphoid structures combined with biomarkers of inflammation are associated with the efficacy of neoadjuvant immunochemotherapy in resectable non‐small cell lung cancer: A retrospective study
Tertiary lymphoid structures combined with biomarkers of inflammation are associated with the efficacy of neoadjuvant immunochemotherapy in resectable non‐small cell lung cancer: A retrospective study Open
Background Neoadjuvant immunochemotherapy can effectively downstage tumors and reduce the risk of postoperative recurrence and distant metastasis in patients with non‐small cell lung cancer (NSCLC). In this study, we investigated the corre…
View article: Chinese clinical practice guidelines for the prevention and treatment of radiation‐induced rectal injury
Chinese clinical practice guidelines for the prevention and treatment of radiation‐induced rectal injury Open
Although radiotherapy plays an important role in the treatment of cancer, it may have negative effects in some individuals. Rectal injury is a common adverse effect of abdominal and pelvic radiotherapy. This injury is caused by administeri…