Shuangli Mi
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View article: Benefits of Better Cardiovascular Health for Calcific Aortic Valve Stenosis Stratified by Polygenic Risk Score
Benefits of Better Cardiovascular Health for Calcific Aortic Valve Stenosis Stratified by Polygenic Risk Score Open
With global aging, the prevalence of calcific aortic valve stenosis (CAVS) has significantly increased, and even mild CAVS elevates mortality risk, highlighting an urgent need for preventive strategies. In 153,312 participants, a higher Li…
View article: Photocurrent Generation and Collection in a WSe2-Based Composite Detector
Photocurrent Generation and Collection in a WSe2-Based Composite Detector Open
Two-dimensional (2D) van der Waals materials have been actively investigated for broadband, high-sensitivity, low-power-consumption photodetection owing to their highly customizable band structures and fast interfacial charge transfers. St…
View article: Controllable polarity photoresponse and imaging based on MoS₂/MLG/MoTe₂ heterostructure
Controllable polarity photoresponse and imaging based on MoS₂/MLG/MoTe₂ heterostructure Open
View article: Synaptotagmin-7 deficit causes insulin hypoactivity and contributes to behavioral alterations in mice
Synaptotagmin-7 deficit causes insulin hypoactivity and contributes to behavioral alterations in mice Open
Synaptotagmin-7 (Syt7) KO mice show diurnal fluctuations of mania- and depression-like behavioral abnormalities. Although GluN2B-NMDAR hypoactivity has been shown to be involved in the induction of mania-like behaviors of the Syt7 KO mice …
View article: Supplementary Tables 1, 2 and 4 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients
Supplementary Tables 1, 2 and 4 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open
PDF file - 115K
View article: Supplementary Tables 1, 2 and 4 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients
Supplementary Tables 1, 2 and 4 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open
PDF file - 115K
View article: Supplementary Table 3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients
Supplementary Table 3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open
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View article: Supplementary Figures 1-3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients
Supplementary Figures 1-3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open
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View article: Supplementary Table 3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients
Supplementary Table 3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open
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View article: Data from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients
Data from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open
Purpose: Cell-based approaches were used to identify genetic markers predictive of patients' risk for poor response prior to chemotherapy.Experimental Design: We conducted genome-wide association studies (GWAS) to identify si…
View article: Supplementary Figures 1-3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients
Supplementary Figures 1-3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open
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View article: Data from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients
Data from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open
Purpose: Cell-based approaches were used to identify genetic markers predictive of patients' risk for poor response prior to chemotherapy.Experimental Design: We conducted genome-wide association studies (GWAS) to identify si…
View article: Supplementary Tables 1-4 from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias
Supplementary Tables 1-4 from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias Open
Supplementary Tables 1-4 from Consistent Deregulation of Gene Expression between Human and Murine MLL Rearrangement Leukemias
View article: Data from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias
Data from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias Open
Important biological and pathologic properties are often conserved across species. Although several mouse leukemia models have been well established, the genes deregulated in both human and murine leukemia cells have not been studied syste…
View article: Supplementary Tables 1-4 from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias
Supplementary Tables 1-4 from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias Open
Supplementary Tables 1-4 from Consistent Deregulation of Gene Expression between Human and Murine MLL Rearrangement Leukemias
View article: Data from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias
Data from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias Open
Important biological and pathologic properties are often conserved across species. Although several mouse leukemia models have been well established, the genes deregulated in both human and murine leukemia cells have not been studied syste…
View article: Supplementary Tables 5-8 from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias
Supplementary Tables 5-8 from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias Open
Supplementary Tables 5-8 from Consistent Deregulation of Gene Expression between Human and Murine MLL Rearrangement Leukemias
View article: Supplementary Tables 5-8 from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias
Supplementary Tables 5-8 from Consistent Deregulation of Gene Expression between Human and Murine <i>MLL</i> Rearrangement Leukemias Open
Supplementary Tables 5-8 from Consistent Deregulation of Gene Expression between Human and Murine MLL Rearrangement Leukemias
View article: Implication of a de novo Variant in ciliary rootlet coiled- coil (CROCC) with assimilation of atlas (AOA)
Implication of a de novo Variant in ciliary rootlet coiled- coil (CROCC) with assimilation of atlas (AOA) Open
Assimilation of atlas is a rare skeletal malformation causing nerve compression with high risk of fatal. However, the genetic etiology of assimilation of atlas AOA is currently lacking. In this paper, the whole-exome sequencing (WES) analy…
View article: Dietary Intervention With α-Amylase Inhibitor in White Kidney Beans Added Yogurt Modulated Gut Microbiota to Adjust Blood Glucose in Mice
Dietary Intervention With α-Amylase Inhibitor in White Kidney Beans Added Yogurt Modulated Gut Microbiota to Adjust Blood Glucose in Mice Open
White kidney beans contain α-amylase inhibitors that can be used in diet for weight reduction. In this study, we investigated the potential of white kidney bean ( phaseolus vulgaris L.) extract enriched in α-amylase inhibitor as a food add…
View article: The long noncoding RNA HOTAIRM1 controlled by AML1 enhances glucocorticoid resistance by activating RHOA/ROCK1 pathway through suppressing ARHGAP18
The long noncoding RNA HOTAIRM1 controlled by AML1 enhances glucocorticoid resistance by activating RHOA/ROCK1 pathway through suppressing ARHGAP18 Open
View article: Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells
Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells Open
MicroRNAs in small extracellular vesicle (sEV-miRNAs) have been widely investigated as crucial regulated molecules secreted by tumor cells to communicate with surroundings. It is of great significance to explore the loading mechanism of sE…
View article: Identification of Potential Key lncRNAs in the Context of Mouse Myeloid Differentiation by Systematic Transcriptomics Analysis
Identification of Potential Key lncRNAs in the Context of Mouse Myeloid Differentiation by Systematic Transcriptomics Analysis Open
Hematopoietic differentiation is a well-orchestrated process by many regulators such as transcription factor and long non-coding RNAs (lncRNAs). However, due to the large number of lncRNAs and the difficulty in determining their roles, the…
View article: <i>miR</i> - <i>218</i> - <i>2</i> regulates cognitive functions in the hippocampus through complement component 3–dependent modulation of synaptic vesicle release
<i>miR</i> - <i>218</i> - <i>2</i> regulates cognitive functions in the hippocampus through complement component 3–dependent modulation of synaptic vesicle release Open
Significance Several neurodegenerative and neuropsychiatric disorders with cognitive symptoms show an abnormal expression of microRNA-218 (miR-218). In this study, we demonstrated that miR-218 regulated presynaptic functions and learning r…
View article: RBUD: A New Functional Potential Analysis Approach for Whole Microbial Genome Shotgun Sequencing
RBUD: A New Functional Potential Analysis Approach for Whole Microbial Genome Shotgun Sequencing Open
Whole metagenome shotgun sequencing is a powerful approach to detect the functional potential of microbial communities. Currently, the read-based metagenomics profiling for established database (RBED) method is one of the two kinds of conv…
View article: Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice
Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice Open
Significance The key molecular mechanisms underlying the etiology of bipolar disorder (BD) have remained enigmatic. As BD patients often show comorbidity with insulin/glucose metabolic syndrome, we hypothesized that the central and periphe…
View article: A promising iPS-based single-cell cloning strategy revealing signatures of somatic mutations in heterogeneous normal cells
A promising iPS-based single-cell cloning strategy revealing signatures of somatic mutations in heterogeneous normal cells Open
View article: Tumor-derived circulating exosomal miR-342-5p and miR-574-5p as promising diagnostic biomarkers for early-stage Lung Adenocarcinoma
Tumor-derived circulating exosomal miR-342-5p and miR-574-5p as promising diagnostic biomarkers for early-stage Lung Adenocarcinoma Open
Lung cancer has been the leading cause of cancer morbidity and mortality in recent years. Most lung cancers are often asymptomatic until advanced or metastatic stage. Therefore, looking for the diagnostic biomarker for early-stage lung can…
View article: Author Correction: CRISPR interference-based specific and efficient gene inactivation in the brain
Author Correction: CRISPR interference-based specific and efficient gene inactivation in the brain Open
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