Shuangmin Wang
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View article: Differential Association of Serum TSH with Differentiated Thyroid Cancer Risk by Autoimmune Thyroiditis Status
Differential Association of Serum TSH with Differentiated Thyroid Cancer Risk by Autoimmune Thyroiditis Status Open
Background: While elevated thyroid-stimulating hormone (TSH) is a known risk factor for differentiated thyroid cancer (DTC), it remains unclear whether autoimmune thyroiditis (AT) modifies this association. Clarifying this interaction is c…
View article: Exosomal non-coding RNAs: mediators of crosstalk between cancer and cancer stem cells
Exosomal non-coding RNAs: mediators of crosstalk between cancer and cancer stem cells Open
Current advances in oncology have recognized two distinct cell subpopulations in tumors that include (1) a rare subpopulation, cancer stem cells (CSCs), which is considered to be the “seed” of the tumor, with therapy-resistant properties a…
View article: Exosomal miRNAs: Key Regulators of the Tumor Microenvironment and Cancer Stem Cells
Exosomal miRNAs: Key Regulators of the Tumor Microenvironment and Cancer Stem Cells Open
Exosomes are lipid bilayer vesicles approximately 30–150 nm in diameter that serve as key mediators of intercellular communication. By transporting diverse bioactive molecules, including proteins and nucleic acids, they play a crucial role…
View article: Identification of disulfidptosis-related long non-coding RNA signature to predict the prognosis, immunotherapy, and chemotherapy options in acute myeloid leukemia
Identification of disulfidptosis-related long non-coding RNA signature to predict the prognosis, immunotherapy, and chemotherapy options in acute myeloid leukemia Open
The prognostic model incorporating eight DRLs demonstrates high accuracy and reliability in predicting survival outcomes for AML patients, thereby identifying potential therapeutic targets for future AML treatment strategies.
View article: Advancements in Research on Mesenchymal Stem-Cell-Derived Exosomal miRNAs: A Pivotal Insight into Aging and Age-Related Diseases
Advancements in Research on Mesenchymal Stem-Cell-Derived Exosomal miRNAs: A Pivotal Insight into Aging and Age-Related Diseases Open
Mesenchymal stem cells (MSCs) are capable of differentiating into various cell types and play a crucial role in repairing aging tissues and diseased organs. Aging manifests as a gradual loss of cellular, tissue, and organ function, leading…
View article: Proteomics Identifies LUC7L3 as a Prognostic Biomarker for Hepatocellular Carcinoma
Proteomics Identifies LUC7L3 as a Prognostic Biomarker for Hepatocellular Carcinoma Open
Alternative splicing has been shown to participate in tumor progression, including hepatocellular carcinoma. The poor prognosis of patients with HCC calls for molecular classification and biomarker identification to facilitate precision me…
View article: From PROTAC to TPD: Advances and Opportunities in Targeted Protein Degradation
From PROTAC to TPD: Advances and Opportunities in Targeted Protein Degradation Open
PROTAC is a rapidly developing engineering technology for targeted protein degradation using the ubiquitin–proteasome system, which has promising applications for inflammatory diseases, neurodegenerative diseases, and malignant tumors. Thi…