Shuchi Xia
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View article: MAT2A inhibits the ferroptosis in osteosarcoma progression regulated by miR-26b-5p
MAT2A inhibits the ferroptosis in osteosarcoma progression regulated by miR-26b-5p Open
Osteosarcoma (OS) is the most frequent primary malignant bone tumor. Ferroptosis, a form of regulated cell death, is a key tumor suppression mechanism. Although methionine adenosyltransferase II alpha (MAT2A) has been reported to inhibit s…
View article: IRF2 Destabilizes Oncogenic KPNA2 to Modulate the Development of Osteosarcoma
IRF2 Destabilizes Oncogenic KPNA2 to Modulate the Development of Osteosarcoma Open
Osteosarcomas (OS) are the most common primary malignant bone tumor. Emerging evidence revealed that karyopherin alpha 2 (KPNA2) was strongly associated with the tumorigenesis and development of numerous human cancers. The aim of the prese…
View article: IRF2 Destabilizes Oncogenic KPNA2 to Modulate the Tumorigenesis of Osteosarcoma via Regulating NF-κB/p65
IRF2 Destabilizes Oncogenic KPNA2 to Modulate the Tumorigenesis of Osteosarcoma via Regulating NF-κB/p65 Open
Background: Osteosarcomas (OS) are the most frequent primary malignant bone tumor. Emerging evidence revealed that karyopherin alpha 2 (KPNA2) was strongly associated with the tumorigenesis and development of numerous human cancers. The ai…