Shufang Ye
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View article: TMEM166 negatively regulates unfolded protein response to affect hepatocellular carcinoma cell growth and sorafenib resistance
TMEM166 negatively regulates unfolded protein response to affect hepatocellular carcinoma cell growth and sorafenib resistance Open
Transmembrane protein 166 (TMEM166), an endoplasmic reticulum (ER)-resident membrane protein, exerts anticancer effects by inducing autophagy and apoptosis. Although tissues of various cancers downregulate its expression, the biological fu…
View article: RNF115 deficiency upregulates autophagy and inhibits hepatocellular carcinoma growth
RNF115 deficiency upregulates autophagy and inhibits hepatocellular carcinoma growth Open
View article: ATF4 promotes glutaminolysis and glycolysis in colorectal cancer by transcriptionally inducing SLC1A5
ATF4 promotes glutaminolysis and glycolysis in colorectal cancer by transcriptionally inducing SLC1A5 Open
Glutaminolysis and glycolysis promote the malignant progression of colorectal cancer. The role of activating transcription factor 4 (ATF4) in solute carrier family 1 member 5 (SLC1A5)-mediated glutaminolysis and glycolysis remains to be el…
View article: Deletion of Tmem268 in mice suppresses anti-infectious immune responses by downregulating CD11b signaling
Deletion of Tmem268 in mice suppresses anti-infectious immune responses by downregulating CD11b signaling Open
View article: RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response Open
View article: RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response Open
The E3 ubiquitin ligase RING finger protein 115 (RNF115), also known as breast cancer-associated gene 2 (BCA2), has been linked with the growth of some cancers and immune regulation, which is negatively correlated with prognosis. Here, it …
View article: Isolation and identification of novel angiotensin I-converting enzyme (ACE) inhibitory peptides from Pony Seed and evaluation of the inhibitory mechanisms
Isolation and identification of novel angiotensin I-converting enzyme (ACE) inhibitory peptides from Pony Seed and evaluation of the inhibitory mechanisms Open
View article: Preparation of angiotensin I- converting enzyme (ACE) inhibitory peptides from Tieguanyin tea residue protein using two-step enzymatic hydrolysis
Preparation of angiotensin I- converting enzyme (ACE) inhibitory peptides from Tieguanyin tea residue protein using two-step enzymatic hydrolysis Open
Angiotensin I-converting enzyme inhibitory (ACEI) peptides, released from precursor proteins in vitro and in vivo, have been paid increased attention in the prevention of high blood pressure. In this study, we attempted to prepare novel AC…
View article: RIG-I Promotes Cell Viability, Colony Formation, and Glucose Metabolism and Inhibits Cell Apoptosis in Colorectal Cancer by NF-κB Signaling Pathway
RIG-I Promotes Cell Viability, Colony Formation, and Glucose Metabolism and Inhibits Cell Apoptosis in Colorectal Cancer by NF-κB Signaling Pathway Open
Background. Retinoic acid-inducible gene-I (RIG-I) has crucial effects on various cancers, while RIG-I’s detailed roles and mechanism in colorectal cancer (CRC) are uncovered. Methods. qRT-PCR was used to detect the expression of RIG-I in …
View article: Electroacupuncture combined with Liumotang has beneficial effects on slow transit constipation in rats
Electroacupuncture combined with Liumotang has beneficial effects on slow transit constipation in rats Open
View article: Investigation of mutation of multidrug resistant <i>Helicobacter pylori</i> efflux pump gene based on whole genome sequencing
Investigation of mutation of multidrug resistant <i>Helicobacter pylori</i> efflux pump gene based on whole genome sequencing Open
View article: Does <i>Helicobacter pylori</i> infection affect the structure of bacteria in the gastric mucosa and fluid in patients with chronic antral gastritis?
Does <i>Helicobacter pylori</i> infection affect the structure of bacteria in the gastric mucosa and fluid in patients with chronic antral gastritis? Open
This study aimed to evaluate the composition of the gastric microbiota in the gastric mucosa and gastric fluid of patients with chronic antral gastritis. Specifically, we sought to determine whether Helicobacter pylori (Hp) infection chang…
View article: Klotho‐mediated targeting of <scp>CCL</scp>2 suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments
Klotho‐mediated targeting of <span>CCL</span>2 suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments Open
Senescent microenvironments play an important role in tumor progression. Here, we report that doxorubicin ( DOX )‐pretreated or replicative senescent stromal cells ( WI ‐38 and HUVEC ) promote colorectal cancer ( CRC ) cell growth and inva…
View article: Downregulation of miRNA-214 inhibits cisplatin resistance, cell migration, and epithelial interstitial transformation in gastric cancer SGC-7901/DDP cells
Downregulation of miRNA-214 inhibits cisplatin resistance, cell migration, and epithelial interstitial transformation in gastric cancer SGC-7901/DDP cells Open
View article: Impact of tumour size on metastasis and survival in patients with pancreatic neuroendocrine tumours (PNETs): A population based study
Impact of tumour size on metastasis and survival in patients with pancreatic neuroendocrine tumours (PNETs): A population based study Open
Background: The relationship between tumour size and metastasis rate is poorly recognized in patients with pancreatic neuroendocrine tumours (PNETs). The impact of tumour size on prognosis was controversial in previous investigation…