Shu‐Fen Sun
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View article: Efficacy and safety of a single intra-articular injection of mannitol-combined hyaluronan in patients with knee osteoarthritis – A double-blinded randomized clinical study
Efficacy and safety of a single intra-articular injection of mannitol-combined hyaluronan in patients with knee osteoarthritis – A double-blinded randomized clinical study Open
A single injection of JETKNEE did not show superiority to placebo in the primary outcome (VAS pain), but demonstrated improvements in secondary functional outcomes for 6 months in patients with knee OA.
View article: Different Duration of Prone Positioning Treatment for Patients with Acute Respiratory Distress Syndrome in Intensive Care Unit Patients: A Prospective Randomized Clinical Study
Different Duration of Prone Positioning Treatment for Patients with Acute Respiratory Distress Syndrome in Intensive Care Unit Patients: A Prospective Randomized Clinical Study Open
Introduction: Prolonged prone positioning, exceeding 16 h, has been associated with reduced mortality among patients with moderate to severe acute respiratory distress syndrome (ARDS). Extending the duration of prone positioning may provid…
View article: Association Between Cardiopulmonary Fitness and Degenerative Lumbar Spine Disease in Patients with Heart Failure: a Retrospective Study Using CPET
Association Between Cardiopulmonary Fitness and Degenerative Lumbar Spine Disease in Patients with Heart Failure: a Retrospective Study Using CPET Open
Heart failure (HF) is a complex clinical syndrome characterized by impaired exercise capacity and reduced quality of life. While musculoskeletal conditions such as degenerative lumbar spine disease (DLSD) are common in older adults, their …
View article: Impact of Adiposity on Cardiopulmonary Fitness in Children and Adolescents with Ventricular Septal Defects: a CPET-Based Comparative Study
Impact of Adiposity on Cardiopulmonary Fitness in Children and Adolescents with Ventricular Septal Defects: a CPET-Based Comparative Study Open
Background: Ventricular septal defect (VSD) is the most common congenital heart defect in children. While previously considered benign, recent studies suggest long-term impacts on cardiopulmonary fitness (CPF). Overweight and obesity, incr…
View article: Different Duration of Prone Position Treatment for Patients with Acute Respiratory Distress Syndrome in Intensive Care Unit Patients: A Prospective Randomized Clinical Study
Different Duration of Prone Position Treatment for Patients with Acute Respiratory Distress Syndrome in Intensive Care Unit Patients: A Prospective Randomized Clinical Study Open
Introduction: Prolonged prone positioning, exceeding 16 hours, has been associated with decreased mortality rates among patients diagnosed with moderate to severe acute respiratory distress syndrome (ARDS). Extending the duration of prone …
View article: Minute Ventilation/Carbon Dioxide Production Slope Could Predict Short- and Long-Term Prognosis of Patients After Acute Decompensated Heart Failure
Minute Ventilation/Carbon Dioxide Production Slope Could Predict Short- and Long-Term Prognosis of Patients After Acute Decompensated Heart Failure Open
(1) Background: Heart failure (HF) leads to functional disability and major cardiovascular events (MACEs). Cardiopulmonary exercise testing (CPET) is the gold standard for assessing aerobic capacity and prognostic stratification. This stud…
View article: Assessing the Clinical Effectiveness of an Exergame-Based Exercise Training Program Using Ring Fit Adventure to Prevent and Postpone Frailty and Sarcopenia Among Older Adults in Rural Long-Term Care Facilities: Randomized Controlled Trial
Assessing the Clinical Effectiveness of an Exergame-Based Exercise Training Program Using Ring Fit Adventure to Prevent and Postpone Frailty and Sarcopenia Among Older Adults in Rural Long-Term Care Facilities: Randomized Controlled Trial Open
Background Frailty and sarcopenia are geriatric syndromes of increasing concern and are associated with adverse health outcomes. They are more prevalent among long-term care facility (LTCF) users than among community dwellers. Exercise, es…
View article: When two Z-scores meet—analysis of exercise capacity of children and adolescents with Kawasaki disease by a new Z-score model of coronary artery and a new Z-score evaluating peak oxygen consumption
When two Z-scores meet—analysis of exercise capacity of children and adolescents with Kawasaki disease by a new Z-score model of coronary artery and a new Z-score evaluating peak oxygen consumption Open
Background Coronary artery (CA) Z-score system is widely used to define CA aneurysm (CAA). Children and adolescents after acute stage of Kawasaki disease (KD-CA) have a higher risk of developing CAAs if their CA Z-score ≥ 2.5. Z-score syst…
View article: Relationship Between NDEL1 Anomaly, Lissencephaly, and Developmental Delay: A Case Report
Relationship Between NDEL1 Anomaly, Lissencephaly, and Developmental Delay: A Case Report Open
Background: Nuclear-distribution element-like 1 (NDEL1) anomaly is a rare genetic condition associated with neurodevelopmental disorders, such as brain malformations, seizures, lissencephaly, and cognitive impairment. However, the clinical…
View article: When two Z-scores meet - Analysis of exercise capacity of children and adolescents with Kawasaki disease by a new Z-score model of coronary artery and a new Z-score evaluating peak oxygen consumption
When two Z-scores meet - Analysis of exercise capacity of children and adolescents with Kawasaki disease by a new Z-score model of coronary artery and a new Z-score evaluating peak oxygen consumption Open
Background Coronary artery (CA) Z-score system is widely used to define CA aneurysm (CAA). Children and adolescents after acute stage of Kawasaki disease (KD-CA) have a higher risk of developing CAAs if their CA Z-score ≥ 2.5. Z-score syst…
View article: Cervical cord compression with lower limb sensory disturbance: three case reports and a literature review
Cervical cord compression with lower limb sensory disturbance: three case reports and a literature review Open
Lower limb sensory disturbance can be a false localizing sign of cervical spondylotic myelopathy. It may lead to delayed or missed diagnosis, resulting in an inappropriate management plan, especially in the presence of concurrent lumbar le…
View article: Using exergame-based exercise to prevent and postpone the loss of muscle mass, muscle strength, cognition, and functional performance among elders in rural long-term care facilities: A protocol for a randomized controlled trial
Using exergame-based exercise to prevent and postpone the loss of muscle mass, muscle strength, cognition, and functional performance among elders in rural long-term care facilities: A protocol for a randomized controlled trial Open
Objective Elderly individuals in long-term care facilities (LTCFs) have a higher prevalence of sarcopenia than those in the community. Exercise is the gold standard for preventing and treating sarcopenia. Regarding exercise, multicomponent…
View article: Serial Exercise Testing and Echocardiography Findings of Patients With Kawasaki Disease
Serial Exercise Testing and Echocardiography Findings of Patients With Kawasaki Disease Open
Objective Kawasaki disease (KD) is the most common form of pediatric vasculitis. We evaluated the influence of KD on cardiopulmonary function and analyzed the echocardiographic findings of patients with KD through serial follow-ups from ch…
View article: Poststroke Swallowing Rehabilitation and Recent Development
Poststroke Swallowing Rehabilitation and Recent Development Open
Dysphagia is a common poststroke complication. It is associated with aspiration, malnutrition, dehydration, and disability, and it may increase the risk of pneumonia, and even death. Early diagnosis and treatment of patients with dysphagia…
View article: Cervical Cord Compression With Lower Limbs Sensory Disturbance Presentation: Three Case Reports and Literature Review
Cervical Cord Compression With Lower Limbs Sensory Disturbance Presentation: Three Case Reports and Literature Review Open
Background: Lower limb sensory disturbance presentation can be a false localizing cervical cord compressive myelopathy (CSM). It may lead to delayed or missed diagnosis, resulting in the wrong management plan, especially in the presence of…
View article: Novel inflammatory markers in the blood of patients with knee synovitis
Novel inflammatory markers in the blood of patients with knee synovitis Open
Objective Synovitis is a joint disease that seriously affects patient quality of life, but there are currently no diagnostic markers. The albumin to fibrinogen ratio (AFR) and monocyte to lymphocyte ratio (MLR) are non-invasive and cost-ef…
View article: Anterior cervical surgery to treat diffuse idiopathic skeletal hypertrophic combined with cervical disc herniation
Anterior cervical surgery to treat diffuse idiopathic skeletal hypertrophic combined with cervical disc herniation Open
Rationale: Diffuse idiopathic skeletal hyperostosis (DISH) is a skeletal disease characterized by calcification of anterolateral ligaments of the spine and the rest of the body. DISH combined with disc herniation induces complex symptoms a…
View article: Clinical Characteristics and Predictors of Mortality in Critically Ill Adult Patients with Influenza Infection
Clinical Characteristics and Predictors of Mortality in Critically Ill Adult Patients with Influenza Infection Open
Patients with influenza infection may develop acute respiratory distress syndrome (ARDS), which is associated with high mortality. Some patients with ARDS receiving extracorporeal membrane oxygenation (ECMO) support die of infectious compl…
View article: Serial cardiopulmonary exercise testing in an asymptomatic young female receiving percutaneous balloon dilatation for cor triatriatum sinistrum at an early age
Serial cardiopulmonary exercise testing in an asymptomatic young female receiving percutaneous balloon dilatation for cor triatriatum sinistrum at an early age Open
A young female was diagnosed as classic cor triatriatum sinistrum (CTS) at 38 months old incidentally and she received percutaneous catheter-based balloon dilatation twice at 41 and 48 months old. She took regular follow-up by echocardiogr…
View article: Successful management of a tooth with endodontic-periodontal lesion: A case report
Successful management of a tooth with endodontic-periodontal lesion: A case report Open
Despite the poor prognosis associated with many endodontic lesions, this case report highlights that a good prognosis is still possible for an endodontic lesion with apical and periodontal bone loss. In this case, it was achieved via succe…
View article: Glycemic variability in critically ill patients: risk factors and association with mortality
Glycemic variability in critically ill patients: risk factors and association with mortality Open
To the Editor: Glycemic variability (GV) has a significant influence on the outcome in critically ill patients.[1–4] Diabetic status of the patient affects the relationship between GV and mortality; increased GV is a more potent risk facto…
View article: Comparison of cardiorespiratory fitness between preschool children with normal and excess body adipose ~ An observational study
Comparison of cardiorespiratory fitness between preschool children with normal and excess body adipose ~ An observational study Open
Preschoolers with excess body adipose had lower CRF significantly during treadmill exercise testing. Weight control and health promotion should start as early as possible.