Shuhei Osaki
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View article: A comparative analysis of hand sarcoma by anatomical site: A case series
A comparative analysis of hand sarcoma by anatomical site: A case series Open
Hand sarcomas are very rare, and few studies have focused on their anatomical distribution, such as involvement of the fingers vs. the palm/dorsum (PD). The present study reviewed 24 cases of hand sarcomas identified from medical records o…
View article: Digital Engagement in AYA Cancer Survivors: Case Reports on the Role of Social Media Video Posting in Vocational Support
Digital Engagement in AYA Cancer Survivors: Case Reports on the Role of Social Media Video Posting in Vocational Support Open
View article: Developmental Patterns and Risk Factors of Scoliosis After Hemipelvectomy for the Pelvic Bone Tumor
Developmental Patterns and Risk Factors of Scoliosis After Hemipelvectomy for the Pelvic Bone Tumor Open
Background: Postoperative scoliosis is often seen after hemipelvectomy for malignancies involving the pelvic area, but the details remain unclear. The objectives were to investigate the development patterns and risk factors of scoliosis af…
View article: High‐quality expert annotations enhance artificial intelligence model accuracy for osteosarcoma X‐ray diagnosis
High‐quality expert annotations enhance artificial intelligence model accuracy for osteosarcoma X‐ray diagnosis Open
Primary malignant bone tumors, such as osteosarcoma, significantly affect the pediatric and young adult populations, necessitating early diagnosis for effective treatment. This study developed a high‐performance artificial intelligence (AI…
View article: A vessel sealing system can help reduce the risk of postoperative complications after tumour resection in the medial thigh
A vessel sealing system can help reduce the risk of postoperative complications after tumour resection in the medial thigh Open
Aims The risk of postoperative complications after resection of soft-tissue sarcoma in the medial thigh is higher than in other locations. This study investigated whether a vessel sealing system (VSS) could help reduce the risk of postoper…
View article: Supplementary Figure 5 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 5 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 261K, Chronological change of p21 expression in SaOS-2 cells after Ad-p53 infection
View article: Supplementary Methods and Figure Legend from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Methods and Figure Legend from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 99K
View article: Supplementary Figure 3 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 3 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 139K, Expression of endogenous p53 protein in SaOS-2 and MNNG/HOS cells
View article: Supplementary Figure 5 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 5 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 261K, Chronological change of p21 expression in SaOS-2 cells after Ad-p53 infection
View article: Supplementary Figure 2 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 2 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 334K, The ID50 values of OBP-702 and Ad-p53 in SaOS-2 and MNNG/HOS cells
View article: Data from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Data from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
Tumor suppressor p53 is a multifunctional transcription factor that regulates diverse cell fates, including apoptosis and autophagy in tumor biology. p53 overexpression enhances the antitumor activity of oncolytic adenoviruses; however, th…
View article: Supplementary Figure 6 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 6 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 852K, Immunohistochemistry of MNNG/HOS tumors
View article: Data from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Data from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
Tumor suppressor p53 is a multifunctional transcription factor that regulates diverse cell fates, including apoptosis and autophagy in tumor biology. p53 overexpression enhances the antitumor activity of oncolytic adenoviruses; however, th…
View article: Supplementary Figure 4 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 4 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 213K, Quantitative measurement of viral DNA replication in SaOS-2 cells infected with OBP-702 or OBP-301
View article: Supplementary Figure 1 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 1 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 250K, The structures of OBP-301 and OBP-702
View article: Supplementary Figure 1 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 1 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 250K, The structures of OBP-301 and OBP-702
View article: Supplementary Figure 6 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 6 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 852K, Immunohistochemistry of MNNG/HOS tumors
View article: Supplementary Figure 4 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 4 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 213K, Quantitative measurement of viral DNA replication in SaOS-2 cells infected with OBP-702 or OBP-301
View article: Supplementary Figure 2 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 2 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 334K, The ID50 values of OBP-702 and Ad-p53 in SaOS-2 and MNNG/HOS cells
View article: Supplementary Methods and Figure Legend from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Methods and Figure Legend from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 99K
View article: Supplementary Figure 3 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells
Supplementary Figure 3 from Dual Programmed Cell Death Pathways Induced by p53 Transactivation Overcome Resistance to Oncolytic Adenovirus in Human Osteosarcoma Cells Open
PDF file - 139K, Expression of endogenous p53 protein in SaOS-2 and MNNG/HOS cells
View article: Study protocol for the G-SPIRIT trial: a randomised, placebo-controlled, double-blinded phase III trial of granulocyte colony-stimulating factor-mediated neuroprotection for acute spinal cord injury
Study protocol for the G-SPIRIT trial: a randomised, placebo-controlled, double-blinded phase III trial of granulocyte colony-stimulating factor-mediated neuroprotection for acute spinal cord injury Open
Introduction Granulocyte colony-stimulating factor (G-CSF) is generally used for neutropaenia. Previous experimental studies revealed that G-CSF promoted neurological recovery after spinal cord injury (SCI). Next, we moved to early phase o…