Shuhua Yuan
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View article: Evaluating large language models in pediatric fever management: a two-layer study
Evaluating large language models in pediatric fever management: a two-layer study Open
Background Pediatric fever is a prevalent concern, often causing parental anxiety and frequent medical consultations. While large language models (LLMs) such as ChatGPT, Perplexity, and YouChat show promise in enhancing medical communicati…
View article: Changes in lung function in children after pneumonia: a multicenter study
Changes in lung function in children after pneumonia: a multicenter study Open
View article: Enhancing pediatric asthma management in underdeveloped regions through ChatGPT training for doctors: a randomized controlled trial
Enhancing pediatric asthma management in underdeveloped regions through ChatGPT training for doctors: a randomized controlled trial Open
Background Childhood asthma represents a significant challenge globally, especially in underdeveloped regions. Recent advancements in Large Language Models (LLMs), such as ChatGPT, offer promising improvements in medical service quality. M…
View article: Global, regional and national burden of asthma from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021
Global, regional and national burden of asthma from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021 Open
Background Asthma represents a significant global health challenge, exhibiting considerable variation in prevalence, incidence, mortality and disability-adjusted life years (DALYs) across regions and countries. This study evaluates global,…
View article: Local Versus Systemic Cytokine Dynamics in Pediatric Pneumonia
Local Versus Systemic Cytokine Dynamics in Pediatric Pneumonia Open
No significant correlation was observed between most local and systemic cytokines in children with pneumonia. The observed elevation of specific cytokines such as IL‐2, IL‐2R, and IL‐4 in the BALF of pneumonia patients, alongside increases…
View article: Exploring the prevalence and chest CT predictors of Long COVID in children: a comprehensive study from Shanghai and Linyi
Exploring the prevalence and chest CT predictors of Long COVID in children: a comprehensive study from Shanghai and Linyi Open
Introduction COVID-19 constitutes a pandemic of significant detriment to human health. This study aimed to investigate the prevalence of Long COVID following SARS-CoV-2 infection, analyze the potential predictors of chest CT for the develo…
View article: Association of obesity with osteoporotic fracture risk in individuals with bone metabolism-related conditions: a cross sectional analysis
Association of obesity with osteoporotic fracture risk in individuals with bone metabolism-related conditions: a cross sectional analysis Open
Introduction This study aimed to investigate the individual and composite associations of different indices of obesity on osteoporotic fractures at three different sites among individuals affected by conditions influencing bone metabolism.…
View article: The correlation between selenium intake and lung function in asthmatic people: a cross-sectional study
The correlation between selenium intake and lung function in asthmatic people: a cross-sectional study Open
Objective This study aimed to examine the correlation between selenium intake and lung function in asthmatic people. Methods A total of 4,541 individuals in the US National Health and Nutrition Examination Survey (NHANES) were included in …
View article: Meta: Data Compression and Event Detection Grand Challenge 2024 With SPRSound Dataset
Meta: Data Compression and Event Detection Grand Challenge 2024 With SPRSound Dataset Open
View article: The combination model of serum occludin and clinical risk factors improved the efficacy for predicting hemorrhagic transformation in stroke patients with recanalization
The combination model of serum occludin and clinical risk factors improved the efficacy for predicting hemorrhagic transformation in stroke patients with recanalization Open
The combination of serum occludin and clinical risk factors significantly improved the prediction efficacy for HT, providing a novel potential prediction model to screen for patients with high risk of HT before recanalization in acute isch…
View article: Allergic diseases aggravate the symptoms of SARS-CoV-2 infection in China
Allergic diseases aggravate the symptoms of SARS-CoV-2 infection in China Open
Background The relationship between allergic diseases and the adverse outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a subject of controversy. This study aimed to investigate the association bet…
View article: Normobaric Hyperoxia Combined with Endovascular Treatment Based on Temporal Gradient: A dose-escalation study
Normobaric Hyperoxia Combined with Endovascular Treatment Based on Temporal Gradient: A dose-escalation study Open
BACKGROUND Normobaric hyperoxia (NBO) has neuroprotective effects in acute ischemic stroke (AIS). Thus, we aimed to identify the optimal NBO treatment duration combined with endovascular treatment (EVT). METHODS Patients with acute stroke …
View article: Comparison of respiratory pathogens in children with community-acquired pneumonia before and during the COVID-19 pandemic
Comparison of respiratory pathogens in children with community-acquired pneumonia before and during the COVID-19 pandemic Open
Background Multifaceted non-pharmaceutical interventions during the COVID-19 pandemic have not only reduced the transmission of SARS-CoV2, but have had an effect on the prevalence of other pathogens. This retrospective study aimed to compa…
View article: Outcomes of Holmium Laser, Cryoablation, and Budesonide Inhalation for Treating Severe Central Airway Stenosis in Infants
Outcomes of Holmium Laser, Cryoablation, and Budesonide Inhalation for Treating Severe Central Airway Stenosis in Infants Open
Holmium laser with cryoablation followed by budesonide inhalation therapy safely and effectively cleans stenotic tissues and maintains airway reopening. Balloon dilation after holmium laser is recommended for treating web-like stenosis.
View article: Association of serum occludin levels and perihematomal edema volumes in intracranial hemorrhage patients
Association of serum occludin levels and perihematomal edema volumes in intracranial hemorrhage patients Open
Background and Purpose Perihematomal edema (PHE) is one of the severe secondary damages following intracranial hemorrhage (ICH). Studies showed that blood–brain barrier (BBB) injury contributes to the development of PHE. Previous studies s…
View article: Comparison of respiratory pathogens in children with community-acquired pneumonia before and during the COVID-19 Pandemic
Comparison of respiratory pathogens in children with community-acquired pneumonia before and during the COVID-19 Pandemic Open
Background Multifaceted non-pharmaceutical interventions during the COVID-19 pandemic have not only reduced the transmission of SARS-CoV2, but have had an effect on the prevalence of other pathogens. This retrospective study aimed to compa…
View article: Huashi baidu granule in the treatment of pediatric patients with mild coronavirus disease 2019: A single-center, open-label, parallel-group randomized controlled clinical trial
Huashi baidu granule in the treatment of pediatric patients with mild coronavirus disease 2019: A single-center, open-label, parallel-group randomized controlled clinical trial Open
Background: Since late February 2022, a wave of coronavirus disease 2019 (COVID-19) mainly caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant rapidly appeared in Shanghai, China. Traditional Chinese …
View article: Prognosis of bronchial asthma in children with different pulmonary function phenotypes: A real-world retrospective observational study
Prognosis of bronchial asthma in children with different pulmonary function phenotypes: A real-world retrospective observational study Open
Objective To follow up on the changes in pulmonary function phenotypes in children with asthma in the first year after diagnosis, and explore the risk factors of poor control in children with good treatment compliance. Methods Children who…
View article: Neuronal Zinc Transporter ZnT3 Modulates Cerebral Ischemia-Induced Blood-Brain Barrier Disruption
Neuronal Zinc Transporter ZnT3 Modulates Cerebral Ischemia-Induced Blood-Brain Barrier Disruption Open
Zinc plays important roles in both physiological and pathological processes in the brain. Accumulation of free zinc in ischemic tissue is recognized to contribute to blood-brain barrier (BBB) disruption following cerebral ischemia, but lit…
View article: A booster shot of vaccine against SARS-CoV-2 should be rigorously promoted and implemented in China
A booster shot of vaccine against SARS-CoV-2 should be rigorously promoted and implemented in China Open
View article: The relationship between early isolation and the duration of viral shedding of mild and asymptomatic infection with SARS-CoV-2 Omicron BA.2 variant
The relationship between early isolation and the duration of viral shedding of mild and asymptomatic infection with SARS-CoV-2 Omicron BA.2 variant Open
View article: Establishment of a Simple Pediatric Lower Respiratory Tract Infections Database Based on the Structured Electronic Medical Records
Establishment of a Simple Pediatric Lower Respiratory Tract Infections Database Based on the Structured Electronic Medical Records Open
Objective This study aimed to establish a pediatric lower respiratory tract infections (PLRTIs) database based on the structured electronic medical records (SEMRs), to provide a brief overview and the usage process of the SEMRs and the dat…
View article: The Relationship Between Daily Dietary Intake of Fiber and Short Sleep Duration in the Presence of Di(2-Ethylhexyl) Phthalate: A Population-Based Study
The Relationship Between Daily Dietary Intake of Fiber and Short Sleep Duration in the Presence of Di(2-Ethylhexyl) Phthalate: A Population-Based Study Open
Objective This study aimed to evaluate the relationship between daily dietary intake of fiber (DDIF) and short sleep duration (SSD) in the presence of di(2-ethylhexyl) phthalate. Methods Data of 13,634 participants in this study were colle…
View article: Normobaric hyperoxia plays a neuroprotective role after cerebral ischemia by maintaining the redox homeostasis and the level of connexin43 in astrocytes
Normobaric hyperoxia plays a neuroprotective role after cerebral ischemia by maintaining the redox homeostasis and the level of connexin43 in astrocytes Open
Introduction Acute cerebral ischemia is caused by an insufficient blood supply to brain tissue. Oxygen therapy, which is able to aid diffusion to reach the ischemic region, has been regarded as a possible treatment for cerebral ischemia. R…
View article: The Association between Daily Dietary Intake of Riboflavin and Lung Function Impairment Related with Dibutyl Phthalate Exposure and the Possible Mechanism
The Association between Daily Dietary Intake of Riboflavin and Lung Function Impairment Related with Dibutyl Phthalate Exposure and the Possible Mechanism Open
This study aimed to evaluate the relationship between the daily dietary intake of riboflavin (DDIR) and impaired lung function associated with dibutyl phthalate (DBP) exposure. Data of 4631 adults in this national cross-sectional survey we…
View article: Emergency Angioplasty or Stenting for Stroke Patients with Intracranial Atherosclerotic Large Vessel Occlusion
Emergency Angioplasty or Stenting for Stroke Patients with Intracranial Atherosclerotic Large Vessel Occlusion Open
Emergency angioplasty or stenting could be a safe and feasible therapeutic option with better outcomes for stroke patients with ICAS-related LVO.
View article: Evaluation of the Clinical Effectiveness of Oseltamivir for Influenza Treatment in Children
Evaluation of the Clinical Effectiveness of Oseltamivir for Influenza Treatment in Children Open
Objective: To estimate the clinical effectiveness of oseltamivir in children with different subtypes of influenza virus infection. Methods: A total of 998 children with acute respiratory infection were enrolled from January to March 2018, …
View article: Higher serum occludin after successful reperfusion Is associated with early neurological deterioration
Higher serum occludin after successful reperfusion Is associated with early neurological deterioration Open
Aims Early neurological deterioration (END) is an important factor that affects prognosis in patients with acute ischemic stroke. We explored the relationship between serum occludin levels after successful reperfusion and END in patients t…
View article: Mycoplasma pneumoniae among Chinese Outpatient Children with Mild Respiratory Tract Infections during the Coronavirus Disease 2019 Pandemic
Mycoplasma pneumoniae among Chinese Outpatient Children with Mild Respiratory Tract Infections during the Coronavirus Disease 2019 Pandemic Open
This is the first and largest prospective, multicenter, active, population-based surveillance study of the epidemiology of Mycoplasma pneumoniae among outpatient children with mild respiratory tract infections (RTIs) during the COVID-19 pa…
View article: The Associations of Caesarean Delivery With Risk of Wheezing Diseases and Changes of T Cells in Children
The Associations of Caesarean Delivery With Risk of Wheezing Diseases and Changes of T Cells in Children Open
Objectives This study aimed to assess the associations of caesarean delivery (CD) with risk of wheezing diseases and changes of immune cells in children. Design The cross-sectional study was conducted between May, 2020 and April, 2021. Set…