Shujie Song
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View article: Efficacy and Safety of Vonoprazan and High‐Dose Amoxicillin Dual Therapy for Rescue Treatment of <i>Helicobacter pylori</i> Infection: A Multicenter Randomized Controlled Trial
Efficacy and Safety of Vonoprazan and High‐Dose Amoxicillin Dual Therapy for Rescue Treatment of <i>Helicobacter pylori</i> Infection: A Multicenter Randomized Controlled Trial Open
Background Vonoprazan and amoxicillin dual therapy has demonstrated favorable efficacy in the initial treatment of Helicobacter pylori ( H. pylori ) infection. This study aimed to evaluate the efficacy and safety of vonoprazan and high‐dos…
View article: Microglial cGAS Deletion Preserves Intercellular Communication and Alleviates Amyloid‐β‐Induced Pathogenesis of Alzheimer's Disease
Microglial cGAS Deletion Preserves Intercellular Communication and Alleviates Amyloid‐β‐Induced Pathogenesis of Alzheimer's Disease Open
Innate immune activation plays a crucial role in the pathogenesis of Alzheimer's disease (AD) and related dementias (ADRD). The cytosolic DNA sensing pathway, involving cGAMP synthase (cGAS) and Stimulator of Interferon Genes (STING), has …
View article: [Uterine and Adnexal Metastasis of Lung Adenocarcinoma:
A Case Report and Literature Review].
[Uterine and Adnexal Metastasis of Lung Adenocarcinoma:
A Case Report and Literature Review]. Open
Primary bronchial lung cancer, commonly known as lung cancer, is one of the malignant tumors with high morbidity and mortality in the world. In recent years, the incidence of lung cancer in women has increased, and most of them are lung ad…
View article: HADHA Regulates Respiratory Complex Assembly and Couples FAO and OXPHOS
HADHA Regulates Respiratory Complex Assembly and Couples FAO and OXPHOS Open
Oxidative phosphorylation (OXPHOS) and fatty acid oxidation (FAO) are key bioenergetics pathways. The machineries for both processes are localized in mitochondria. Secondary OXPHOS defects have been documented in patients with primary FAO …
View article: An Efficient BP Algorithm Based on TSU-ICSI Combined with GPU Parallel Computing
An Efficient BP Algorithm Based on TSU-ICSI Combined with GPU Parallel Computing Open
High resolution remains a primary goal in the advancement of synthetic aperture radar (SAR) technology. The backprojection (BP) algorithm, which does not introduce any approximation throughout the imaging process, is broadly applicable and…
View article: Data from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Data from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development Open
Malignant rhabdoid tumors (MRT), a pediatric cancer that most frequently appears in the kidney and brain, generally lack SNF5 (SMARCB1/INI1), a subunit of the SWI/SNF chromatin-remodeling complex. Recent studies have established that multi…
View article: Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development Open
Supplementary Figure S1. This supplementary figure shows that SNF5 KD in normal human fibroblasts does not alter mRNA levels of SWI/SNF components.
View article: Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development Open
Supplementary Table 2. A table of qPCR primers used for these studies.
View article: Supplementary Table 1 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Supplementary Table 1 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
XLSX file - 623K, Genes that are upregulated or downregulated by BRG1.
View article: Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development Open
Supplementary Figure S2. This figure demonstrates the onset of replicative senescence after SNF5 KD in normal human fibroblasts.
View article: Data from Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non–Small Cell Lung Carcinoma
Data from Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non–Small Cell Lung Carcinoma Open
The NF-E2–related factor 2 (referred to as NRF2) transcription factor binds antioxidant responsive elements within the promoters of cytoprotective genes to induce their expression. Next-generation sequencing studies in lung cancer have sho…
View article: Supplementary Table 4 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Supplementary Table 4 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
XLSX file - 90K, Genes upregulated by BRG1 or 5dAzaC.
View article: Supplementary Table 7 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Supplementary Table 7 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
XLSX file - 71K, Genes upregulated by 5dAzaC or TSA.
View article: Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development Open
Supplementary Figure S1. This supplementary figure shows that SNF5 KD in normal human fibroblasts does not alter mRNA levels of SWI/SNF components.
View article: Supplementary Table 4 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Supplementary Table 4 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
XLSX file - 90K, Genes upregulated by BRG1 or 5dAzaC.
View article: Supplementary Table 3 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Supplementary Table 3 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
XLSX file - 67K, Genes upregulated by TSA only.
View article: Data from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Data from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development Open
Malignant rhabdoid tumors (MRT), a pediatric cancer that most frequently appears in the kidney and brain, generally lack SNF5 (SMARCB1/INI1), a subunit of the SWI/SNF chromatin-remodeling complex. Recent studies have established that multi…
View article: Supplementary Table 1 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Supplementary Table 1 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
XLSX file - 623K, Genes that are upregulated or downregulated by BRG1.
View article: Supplementary Table 6 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Supplementary Table 6 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
XLSX file - 63K, Genes upregulated by any treatment.
View article: Data from Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non–Small Cell Lung Carcinoma
Data from Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non–Small Cell Lung Carcinoma Open
The NF-E2–related factor 2 (referred to as NRF2) transcription factor binds antioxidant responsive elements within the promoters of cytoprotective genes to induce their expression. Next-generation sequencing studies in lung cancer have sho…
View article: Supplementary Table 1 from Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non–Small Cell Lung Carcinoma
Supplementary Table 1 from Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non–Small Cell Lung Carcinoma Open
Table shows genes with significantly altered expression by RNA-seq after BRG1 or BRM knockout.
View article: Data from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Data from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
The SWI/SNF chromatin-remodeling complex regulates gene expression and alters chromatin structures in an ATP-dependent manner. Recent sequencing efforts have shown mutations in BRG1 (SMARCA4), one of two mutually exclusive AT…
View article: Supplementary Table 3 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Supplementary Table 3 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
XLSX file - 67K, Genes upregulated by TSA only.
View article: Supplementary Figures from Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non–Small Cell Lung Carcinoma
Supplementary Figures from Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non–Small Cell Lung Carcinoma Open
Supplementary Figure 1 shows BRG1 deficiency activates transcription of a subset of NRF2 target genes in second H358 BRG1 knockdown cell line; Supplementary Figure 2 shows western blot of BRG1 and BRM knockout samples used for RNA-seq.
View article: Data from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Data from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
The SWI/SNF chromatin-remodeling complex regulates gene expression and alters chromatin structures in an ATP-dependent manner. Recent sequencing efforts have shown mutations in BRG1 (SMARCA4), one of two mutually exclusive AT…
View article: Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development Open
Supplementary Table 1. A table of the antibodies and their sources used for these studies
View article: Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development Open
Supplementary Table 2. A table of qPCR primers used for these studies.
View article: Supplementary Figure 1 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Supplementary Figure 1 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
PDF file - 4305K, Validation of gene expression for microarray and RGLS analyses; RGLS analysis of the A427 cell line.
View article: Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
Data Supplement from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development Open
Supplementary Figure S2. This figure demonstrates the onset of replicative senescence after SNF5 KD in normal human fibroblasts.
View article: Supplementary Table 7 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development
Supplementary Table 7 from Gene Silencing Associated with SWI/SNF Complex Loss during NSCLC Development Open
XLSX file - 71K, Genes upregulated by 5dAzaC or TSA.