Shulamith Rizel
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View article: Ten-year clinical outcomes in N0 ER+ breast cancer patients with Recurrence Score-guided therapy
Ten-year clinical outcomes in N0 ER+ breast cancer patients with Recurrence Score-guided therapy Open
The 21-gene Recurrence Score (RS) assay is a validated prognosticator/predictor of chemotherapy (CT) benefit in early-stage estrogen receptor (ER)-positive breast cancer (BC). Long-term data from real-life clinical practice where treatment…
View article: Premature ovarian aging in <i>BRCA</i> carriers: a prototype of systemic precocious aging?
Premature ovarian aging in <i>BRCA</i> carriers: a prototype of systemic precocious aging? Open
Our results suggest a link between BRCA mutation, accelerated ovarian aging and systemic aging-related pathophysiology.
View article: The association between smoking and breast cancer characteristics and outcome
The association between smoking and breast cancer characteristics and outcome Open
Smoking had no clinically significant influence on tumor characteristics and outcome among women with estrogen receptor positive, HER2 negative, early breast cancer. As the study was limited to a specific subgroup of the breast cancer popu…
View article: Factors Affecting Communication Patterns between Oncology Staff and Family Members of Deceased Patients: A Cross-Sectional Study
Factors Affecting Communication Patterns between Oncology Staff and Family Members of Deceased Patients: A Cross-Sectional Study Open
Perspectives regarding bereavement actions differ significantly across medical professions, work settings, and self-defined religions. Additional guidance and education regarding bereavement actions is warranted.
View article: The Association between Treatment for Metabolic Disorders and Breast Cancer Characteristics
The Association between Treatment for Metabolic Disorders and Breast Cancer Characteristics Open
Purpose . To evaluate the associations between metformin, insulin, statins, and levothyroxine and breast cancer characteristics and outcome. Methods . Retrospective chart review of patients treated in our institute for early estrogen recep…
View article: Long-Term Follow-Up of Chemotherapy-Induced Ovarian Failure in Young Breast Cancer Patients: The Role of Vascular Toxicity
Long-Term Follow-Up of Chemotherapy-Induced Ovarian Failure in Young Breast Cancer Patients: The Role of Vascular Toxicity Open
Background. We previously reported that chemotherapy-induced ovarian toxicity may result from acute vascular insult, demonstrated by decreased ovarian blood flow and diminished post-treatment anti-Müllerian hormone (AMH) levels. In the pre…
View article: Lapatinib or Trastuzumab Plus Taxane Therapy for Human Epidermal Growth Factor Receptor 2–Positive Advanced Breast Cancer: Final Results of NCIC CTG MA.31
Lapatinib or Trastuzumab Plus Taxane Therapy for Human Epidermal Growth Factor Receptor 2–Positive Advanced Breast Cancer: Final Results of NCIC CTG MA.31 Open
Purpose The efficacy of lapatinib versus trastuzumab combined with taxanes in the first-line setting of human epidermal growth factor receptor 2 (HER2) –positive metastatic breast cancer (BC) is unknown. Patients and Methods The MA.31 tria…