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View article: Evolutionary Changes of <i>GT1</i> Provide Insights Into the Adaptation of Butterflies to Plant Feeding
Evolutionary Changes of <i>GT1</i> Provide Insights Into the Adaptation of Butterflies to Plant Feeding Open
Glycosyltransferase 1 ( GT1 ) genes are involved in insect detoxification, olfactory perception, and endogenous metabolic regulation, and they play a role in the adaptation of butterflies to their specific feeding habits. However, their ev…
View article: Shuangshen granules enhance anti-PD1 therapy efficacy in lung adenocarcinoma by modulating myeloid-derived suppressor cell-induced T cell exhaustion
Shuangshen granules enhance anti-PD1 therapy efficacy in lung adenocarcinoma by modulating myeloid-derived suppressor cell-induced T cell exhaustion Open
Background Worldwide, lung cancer is the most common cause of cancer-related deaths. Molecular targeted therapies and immunotherapies for non-small-cell lung cancer (NSCLC) have improved outcomes markedly over the past two decades. However…
View article: Bidirectional Mendelian randomization and immune cell mediation analysis: A STROBE-MR study unveiling the causal link between non-small cell and small cell lung cancers
Bidirectional Mendelian randomization and immune cell mediation analysis: A STROBE-MR study unveiling the causal link between non-small cell and small cell lung cancers Open
A certain number of non-small cell lung cancer (NSCLC) transform into small cell lung cancer (SCLC) during treatment, presenting a poorer prognosis compared to the original tumor. However, the causal association between NSCLC and SCLC rema…
View article: Evolutionary Dynamics of Glycoside Hydrolase Family 1 Provide Insights into Insect–Plant Interactions in Lepidoptera
Evolutionary Dynamics of Glycoside Hydrolase Family 1 Provide Insights into Insect–Plant Interactions in Lepidoptera Open
Glycoside hydrolase family 1 (GH1) enzymes are essential for plant cell wall digestion and the detoxification of plant metabolites in insects, yet their evolutionary history in Lepidoptera remains unresolved. This study systematically iden…
View article: Comprehensive identification of cotton EPF/EPFL receptors and functional characterization of the GhEPFL1-1-GhER1 module in drought tolerance
Comprehensive identification of cotton EPF/EPFL receptors and functional characterization of the GhEPFL1-1-GhER1 module in drought tolerance Open
The development of stomatal lineage cells in terrestrial plants is tightly regulated by epidermal patterning factors (EPFs/EPFLs) and their downstream receptors, including ERECTA, TOO MANY MOUTHS (TMM), and SOMATIC EMBRYOGENESIS RECEPTOR K…
View article: An Integrative Phylogenetic Analysis of the Genus Rhynchium Spinola (Hymenoptera: Vespidae: Eumeninae) from China Based on Morphology, Genomic Data and Geographical Distribution
An Integrative Phylogenetic Analysis of the Genus Rhynchium Spinola (Hymenoptera: Vespidae: Eumeninae) from China Based on Morphology, Genomic Data and Geographical Distribution Open
The species of the genus Rhynchium Spinola are important natural insect control resources and widespread in the Old World. Due to the various color patterns of several species in China, it is difficulty to accurately classify and identify …
View article: <i>Cryptocercus</i> genomes expand knowledge of adaptations to xylophagy and termite sociality
<i>Cryptocercus</i> genomes expand knowledge of adaptations to xylophagy and termite sociality Open
Subsociality and wood-eating or xylophagy are understood as key drivers in the evolution of eusociality in Blattodea (cockroaches and termites), two features observed in the cockroach genus Cryptocercus , the sister group of all termites. …
View article: Unravelling termite evolution with 47 high-resolution genome assemblies
Unravelling termite evolution with 47 high-resolution genome assemblies Open
Termites are a lineage of social cockroaches abundant in tropical ecosystems where they are key decomposers of organic matter from wood to soil. Despite their ecological significance, only a handful of reference-quality termite genomes hav…
View article: Study of Mitogenomes Provides Implications for the Phylogenetics and Evolution of the Infraorder Muscomorpha in Diptera
Study of Mitogenomes Provides Implications for the Phylogenetics and Evolution of the Infraorder Muscomorpha in Diptera Open
The Muscomorpha is one of the most species‐rich brachyceran groups in Diptera, with many species serving as important disease vectors; however, its high‐level phylogenetic relationships have long been controversial and unsolved. This study…
View article: Effect of pre-strain on dynamic mechanical properties of Ti-6Cr-5Mo-5V-4Al titanium alloy
Effect of pre-strain on dynamic mechanical properties of Ti-6Cr-5Mo-5V-4Al titanium alloy Open
The effect of quasi-static pre-deformation on the dynamic properties of Ti-6Cr-5Mo-5V-4Al titanium alloy was studied. The results revealed that as the pre-tension deformation increased, the average dynamic flow stress was slightly decrease…
View article: Structures and genetic information of control region in mitogenomes of Odonata
Structures and genetic information of control region in mitogenomes of Odonata Open
Mitogenome data of Odonata is accumulating and widely used in phylogenetic analysis. However, noncoding regions, especially control region, were usually omitted from the phylogenetic reconstruction. In an effort to uncover the phylogenetic…
View article: Duplications and Losses of the Detoxification Enzyme Glycosyltransferase 1 Are Related to Insect Adaptations to Plant Feeding
Duplications and Losses of the Detoxification Enzyme Glycosyltransferase 1 Are Related to Insect Adaptations to Plant Feeding Open
Insects have developed sophisticated detoxification systems to protect them from plant secondary metabolites while feeding on plants to obtain necessary nutrients. As an important enzyme in the system, glycosyltransferase 1 (GT1) conjugate…
View article: Genome-wide identification reveals conserved carbohydrate-active enzyme repertoire in termites
Genome-wide identification reveals conserved carbohydrate-active enzyme repertoire in termites Open
Termites play an important role as decomposers of organic matter in forests by utilizing their gut symbionts and associated carbohydrate-active enzymes (CAZymes) to digest wood materials. However, there is a limited understanding of the en…
View article: Phylogeny of Rhynchium and Its Related Genera (Hymenoptera: Eumeninae) Based on Universal Single-Copy Orthologs and Ultraconserved Elements
Phylogeny of Rhynchium and Its Related Genera (Hymenoptera: Eumeninae) Based on Universal Single-Copy Orthologs and Ultraconserved Elements Open
The subfamily Eumeninae is a large group of fierce predatory insects that prey mainly on the larvae of Lepidoptera pests. Because of the highly similar morphologies of the genus Rhynchium and its related genera in the subfamily, including …
View article: High-efficiency gene editing in<i>Anopheles sinensis</i>using ReMOT control
High-efficiency gene editing in<i>Anopheles sinensis</i>using ReMOT control Open
CRISPR/Cas9-mediated gene editing provides an effective method for deciphering the molecular mechanisms underlying mosquito development and mosquito-borne disease transmission, as well as for exploring genetic control strategies. However, …
View article: Comparative analysis of adipokinetic hormones and their receptors in Blattodea reveals novel patterns of gene evolution
Comparative analysis of adipokinetic hormones and their receptors in Blattodea reveals novel patterns of gene evolution Open
Adipokinetic hormone (AKH) is a neuropeptide produced in the insect corpora cardiaca that plays an essential role in mobilising carbohydrates and lipids from the fat body to the haemolymph. AKH acts by binding to a rhodopsin‐like G protein…
View article: Mitogenomes of Eight Nymphalidae Butterfly Species and Reconstructed Phylogeny of Nymphalidae (Nymphalidae: Lepidoptera)
Mitogenomes of Eight Nymphalidae Butterfly Species and Reconstructed Phylogeny of Nymphalidae (Nymphalidae: Lepidoptera) Open
The Nymphalidae family of cosmopolitan butterflies (Lepidoptera) comprises approximately 7200 species found on all continents and in all habitats. However, debate persists regarding the phylogenetic relationships within this family. In thi…
View article: Ginseng-containing traditional medicine preparations in combination with fluoropyrimidine-based chemotherapy for advanced gastric cancer: A systematic review and meta-analysis
Ginseng-containing traditional medicine preparations in combination with fluoropyrimidine-based chemotherapy for advanced gastric cancer: A systematic review and meta-analysis Open
Background Ginseng-containing traditional medicine preparations (G-TMPs) in combination with fluoropyrimidine-based chemotherapy (FBC) are well-known treatments for advanced gastric cancer (AGC), with a superior efficacy to FBC alone. Howe…
View article: Advances in the understanding of Blattodea evolution: Insights from phylotranscriptomics and spermathecae
Advances in the understanding of Blattodea evolution: Insights from phylotranscriptomics and spermathecae Open
Cockroaches, an ancient and diverse group of insects on earth that originated in the Carboniferous, displays a wide array of morphology or biology diversity. The spermatheca is an organ of the insect reproductive system; the diversity of s…
View article: AsOBP1 is required for host seeking in the malaria vector mosquito, Anopheles sinensis
AsOBP1 is required for host seeking in the malaria vector mosquito, Anopheles sinensis Open
Female adult anautogenous mosquitoes rely heavily on diverse chemical stimuli to locate and discriminate hosts for feeding through their olfactory system. Odorant binding proteins are believed to be the first proteins to interact with semi…
View article: The <i>Drosophila</i>‐parasitizing wasp <i>Leptopilina heterotoma</i>: A comprehensive model system in ecology and evolution
The <i>Drosophila</i>‐parasitizing wasp <i>Leptopilina heterotoma</i>: A comprehensive model system in ecology and evolution Open
The parasitoid Leptopilina heterotoma has been used as a model system for more than 70 years, contributing greatly to diverse research areas in ecology and evolution. Here, we synthesized the large body of work on L. heterotoma with the ai…
View article: Efficacy and Safety of Chinese Herbal Injection Thoracic Perfusion combined with Cisplatin chemotherapy for Lung Cancer Malignant Pleural Effusion: A Systematic Review and Meta-Analysis
Efficacy and Safety of Chinese Herbal Injection Thoracic Perfusion combined with Cisplatin chemotherapy for Lung Cancer Malignant Pleural Effusion: A Systematic Review and Meta-Analysis Open
Purpose To evaluate the efficacy and safety of Chinese herbal injection thoracic perfusion combined with cisplatin chemotherapy for lung cancer patients with MPE. Method Eight databases were searched for articles published from inception t…
View article: The Evolution of Glycoside Hydrolase Family 1 in Insects Related to Their Adaptation to Plant Utilization
The Evolution of Glycoside Hydrolase Family 1 in Insects Related to Their Adaptation to Plant Utilization Open
Insects closely interact with plants with multiple genes involved in their interactions. β-glucosidase, constituted mainly by glycoside hydrolase family 1 (GH1), is a crucial enzyme in insects to digest plant cell walls and defend against …
View article: Complete mitochondrial genomes of <i>Papilio nephelus chaon</i> and <i>Papilio epycides</i> (Lepidoptera: Papilionidae: Papilioninae) and phylogenetic analysis
Complete mitochondrial genomes of <i>Papilio nephelus chaon</i> and <i>Papilio epycides</i> (Lepidoptera: Papilionidae: Papilioninae) and phylogenetic analysis Open
The complete mitochondrial genome (mitogenome) sequences of Papilio nephelus chaon and Papilio epycides were sequenced by Illumina and analyzed in this study. They are 15,287 bp and 15,012 bp in size, respectively, and contains 13 protein-…
View article: Additional file 11 of Eating in a losing cause: limited benefit of modified macronutrient consumption following infection in the oriental cockroach Blatta orientalis
Additional file 11 of Eating in a losing cause: limited benefit of modified macronutrient consumption following infection in the oriental cockroach Blatta orientalis Open
Additional file 11. README.