Explanipedia

Molecular insights into ligand recognition and receptor activation of GPR15 Open

Shutian Chen, Xu Han, Yiming Zhang, Limin Ma, Cuiying Yi , et al. · 2025

Benchmarking cell type and gene set annotation by large language models with AnnDictionary Open

George Crowley, Robert C. Jones, Mark A. Krasnow, Angela Oliveira Pisco, Julia Salzman , et al. · 2025

IGF2BP2 Mediated the Positive Effects of the NAD + in the Decidualization of the Human Endometrial Stromal Cells Open

Minghui Liu, Yao Fu, Shuo Han · 2025

Background The successful decidualization of the endometrium is crucial for human embryo implantation. Impaired decidualization leads to reduced endometrial receptivity and implantation failure. Nicotinamide adenine dinucleotide (NAD+), bo…

Therapeutic <i>Salmonella</i> induces long-term protective trained immunity in NK cells against cancer metastasis Open

Rong Li, Jingchu Hu, Wei Jin, Renhao Li, Yangfan Wu , et al. · 2025

Trained immunity, a form of innate immune memory initially recognized in pathogen defense, has recently been reported to aid in combating cancer. Although trained immunity has been well-characterized in myeloid lineage cells, its presence …

YOLOv5s-TC: An Improved Intelligent Model for Insulator Fault Detection Based on YOLOv5s Open

Yingying Yin, Yunpeng Duan, Xin Wang, Shuo Han, Chengyang Zhou · 2025

Insulators play a pivotal role in power grid infrastructure, offering indispensable electrical insulation and mechanical support. Precise and efficient detection of insulator faults is of paramount importance for safeguarding grid reliabil…

Investigation of hadronic cross sections of cosmic ray carbon and oxygen on BGO from 200 GeV to 10 TeV energy at the DAMPE experiment Open

NULL AUTHOR_ID, Q. An, P. Azzarello, Felicia Barbato, P. Bernardini , et al. · 2025

The Dark Matter Particle Explorer (DAMPE) has made significant progress in measuring the fluxes of cosmic rays. These new measurements are pivotal in advancing our understanding of the origins and propagation mechanisms of cosmic rays. The…

Co-Retention FeaturePyramid Network for Low-dose CTDenoising via Spatialand and Frequency Domain Learning Open

Li Zhou, Bahareh Morovati, Dayang Wang, Yongshun Xu, Shuo Han , et al. · 2025

AGING AND THE MICROBIOME Open

Shuo Han · 2024

This 90-minute session will explore key interactions between aging and the microbiome leveraging studies in animal models and humans. The three invited talks will discuss the following diverse topics in microbe-aging interactions: 1) funct…

Selenium interaction with iron minerals: Quantitative comparison of sorption and coprecipitation impacts on mobility Open

Enrica Balboni, Shuo Han, Mavrik Zavarin · 2024

Characterization of the Bax Inhibitor-1 Family in Cauliflower and Functional Analysis of BobBIL4 Open

Xin Liu, Ning Guo, Shasha Li, Mengmeng Duan, Guixiang Wang , et al. · 2024

The Bax inhibitor-1 (BI-1) gene family, which is important for plant growth, development, and stress tolerance, remains largely unexplored in cauliflower. In this study, we identified and characterized cauliflower BI-1 family genes. Based …

Mapping subcellular RNA localization with proximity labeling Open

Jiapeng Liu, Binglin Zhong, Shuojun Li, Shuo Han · 2024

The subcellular localization of RNA is critical to a variety of physiological and pathological processes. Dissecting the spatiotemporal regulation of the transcriptome is key to understanding cell function and fate. However, it remains cha…

Characterization of the Bax inhibitor-1 Family in Cauliflower and Functional Analysis of BobBIL4 Open

Xin Liu, Ning Guo, Shasha Li, Mengmeng Duan, Guixiang Wang , et al. · 2024

The Bax inhibitor-1 (BI-1) gene family, which is required for plant growth, development, and stress tolerance, remains largely unexplored in cauliflower. In this study, we identified and characterized cauliflower BI-1 family genes. On the …

Molecular and cellular mechanisms of teneurin signaling in synaptic partner matching Open

Chuanyun Xu, Zhuoran Li, Cheng Lyu, Yixin Hu, Colleen N. McLaughlin , et al. · 2024

Molecular and Cellular Mechanisms of Teneurin Signaling in Synaptic Partner Matching Open

Chuanyun Xu, Zhuoran Li, Cheng Lyu, Yixin Hu, Colleen N. McLaughlin , et al. · 2024

SUMMARY In developing brains, axons exhibit remarkable precision in selecting synaptic partners among many non-partner cells. Evolutionally conserved teneurins were the first identified transmembrane proteins that instruct synaptic partner…

Genome-Wide Identification of DUF668 Gene Family and Expression Analysis under F. solani, Chilling, and Waterlogging Stresses in Zingiber officinale Open

Shuo Han, Xiaowen Han, Chuandong Qi, Fengling Guo, Junliang Yin , et al. · 2024

The domains of unknown function (DUF) superfamilies contain proteins with conserved amino acid sequences without known functions. Among them, DUF668 was indicated widely involving the stress response of plants. However, understanding ZoDUF…

Molecular and Cellular Mechanisms of Teneurin Signaling in Synaptic Partner Matching Open

Chuanyun Xu, Zhuoran Li, Cheng Lyu, Yixin Hu, Colleen N. McLaughlin , et al. · 2024

Genome-Wide Identification and Expression Analysis of the SWEET Gene Family in Capsicum annuum L. Open

Xiaowen Han, Shuo Han, Yongxing Zhu, Yiqing Liu, Shenghua Gao , et al. · 2023

Sugars will eventually be exported transporters (SWEETs) are a novel class of sugar transport proteins that play a crucial role in plant growth, development, and response to stress. However, there is a lack of systematic research on SWEETs…

Comprehensive Genome-Wide Identification of the RNA-Binding Glycine-Rich Gene Family and Expression Profiling under Abiotic Stress in Brassica oleracea Open

Mengmeng Duan, Mei Zong, Ning Guo, Shuo Han, Guixiang Wang , et al. · 2023

The RNA-binding glycine-rich proteins (RBGs) of the glycine-rich protein family play vital roles in regulating gene expression both at the transcriptional and post-transcriptional levels. However, the members and functions in response to a…

Genome-Wide Identification, Characterization and Expression Analysis of the TaDUF724 Gene Family in Wheat (Triticum aestivum) Open

Yi Yuan, Xiaohui Yin, Xiaowen Han, Shuo Han, Yiting Li , et al. · 2023

Unknown functional domain (DUF) proteins constitute a large number of functionally uncharacterized protein families in eukaryotes. DUF724s play crucial roles in plants. However, the insight understanding of wheat TaDUF724s is currently lac…

Modeling and experimental investigation of spent fuel disposal in crystalline rocks: FY23 progress report Open

Yifeng Wang, Yongliang Xiong, Teklu Hadgu, Carlos López, Melissa Mills , et al. · 2023

The objective of the crystalline disposal work packages is to advance our understanding of long-term disposal of used fuel in crystalline rocks and to develop necessary experimental and computational capabilities to evaluate various dispos…

Genome-Wide Identification, Characterization, and Expression Profiling of TaDUF668 Gene Family in Triticum aestivum Open

Xiaohui Yin, Yuan Yi, Xiaowen Han, Shuo Han, Yiting Li , et al. · 2023

DUF668s, a plant-specific gene family, encode proteins containing domain of unknown function (DUF) domains. Despite their essential functions, there is a lack of insight into Triticum aestivum TaDUF668s. Here, 31 TaDUF668s were identified …

THE SLEEP THIEF: NOCTURIA, A PERIPHERAL CIRCADIAN DYSFUNCTION Open

Abdallah Al‐Mohammad, Sean Berquist, Shuo Han, Bernardita M. Ljubetic, Butool Durrani , et al. · 2023

PEELing: an integrated and user-centric platform for spatially-resolved proteomics data analysis Open

Xi Peng, Jody Clements, Zuzhi Jiang, Shuo Han, Stephan Preibisch , et al. · 2023

Summary Molecular compartmentalization is vital for cellular physiology. Spatially-resolved proteomics allows biologists to survey protein composition and dynamics with subcellular resolution. Here we present PEELing, an integrated package…

Silica nanoparticles promote wheat growth by mediating hormones and sugar metabolism Open

Yiting Li, Keyong Xi, Xi Liu, Shuo Han, Xiaowen Han , et al. · 2023

Background Silica nanoparticles (SiNPs) have been demonstrated to have beneficial effects on plant growth and development, especially under biotic and abiotic stresses. However, the mechanisms of SiNPs-mediated plant growth strengthening a…

Additional file 1 of Silica nanoparticles promote wheat growth by mediating hormones and sugar metabolism Open

Yiting Li, Keyong Xi, Xi Liu, Shuo Han, Xiaowen Han , et al. · 2023

Additional file 1: Table S1. The primer sequences for qRT-PCR.

Self-supervised E-Swin based transmission line fittings detection Open

Ke Zhang, Ruiheng Zhou, Chaojun Shi, Shuo Han, Mingkun Du , et al. · 2023

目的输电线路金具种类繁多、用处多样，与导线和杆塔安全密切相关。评估金具运行状态并实现故障诊断，需对输电线路金具目标进行精确定位和识别，然而随着无人机巡检采集的数据逐渐增多，将全部数据进行人工标注愈发困难。针对无标注数据无法有效利用的问题，提出一种基于自监督E-Swin Transformer （efficient shifted windows Transformer）的输电线路金具检测模型，充分利用无标注数据提高检测精度。方法首先，为了减少自注意力的计算量、提高模型计…

Preparing potassium fulvic acid based on lignite from different regions of China Open

Qi Gong, Lele Wang, Kexin Tang, Shuo Han, Guochao Wu , et al. · 2022

China is the world’s biggest coal producer and is rich in coal resources. But lignite is one of the coal resources with a lower utilization rate and added value. How to improve its utilization rate and added value has drawn great interest …

Masked Autoencoders for Low dose CT denoising Open

Dayang Wang, Yongshun Xu, Shuo Han, Hengyong Yu · 2022

Low-dose computed tomography (LDCT) reduces the X-ray radiation but compromises image quality with more noises and artifacts. A plethora of transformer models have been developed recently to improve LDCT image quality. However, the success…

In situ cell-type-specific cell-surface proteomic profiling in mice Open

S. Andrew Shuster, Jun Li, Uree Chon, Miley C. Sinantha-Hu, David J. Luginbuhl , et al. · 2022

Cell-surface proteins (CSPs) mediate intercellular communication throughout the lives of multicellular organisms. However, there are no generalizable methods for quantitative CSP profiling in specific cell types in vertebrate tissues. Here…

Search for relativistic fractionally charged particles in space Open

Francesco Alemanno, Corrado Altomare, Q. An, P. Azzarello, Felicia Barbato , et al. · 2022

More than a century after the performance of the oil drop experiment, the possible existence of fractionally charged particles (FCPs) still remains unsettled. The search for FCPs is crucial for some extensions of the Standard Model in part…

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