Shaobo Zhou
YOU?
Author Swipe
View article: Effects of Functional Foods and Dietary Bioactives on Human Health
Effects of Functional Foods and Dietary Bioactives on Human Health Open
Functional foods and dietary bioactives are moving from discovery to translation because we can now engineer structure and exposure together—the two levers that largely determine real-world efficacy [...]
View article: Association of lifestyle, dietary pattern, and liver function with cognition in older adults: findings from a cross-sectional study
Association of lifestyle, dietary pattern, and liver function with cognition in older adults: findings from a cross-sectional study Open
Background Single lifestyle, dietary pattern, and liver function are closely associated with cognitive ability, yet their combined influences on cognition remain unclear. This study aimed to investigate the effects of lifestyle, dietary pa…
View article: Calcium Overload and Apoptosis in Mitochondrial Pathways under Ischemia, Hypoxia, and Epilepsy-Like Conditions in an In Vitro Study
Calcium Overload and Apoptosis in Mitochondrial Pathways under Ischemia, Hypoxia, and Epilepsy-Like Conditions in an In Vitro Study Open
Objective Ischemia and hypoxia are frequently associated with epileptic characteristics, and irregular calcium metabolism can exacerbate neuronal damage. To investigate calcium homeostasis and its effect on neuronal injury, hippocampal HT2…
View article: Gender-, Age-, and Region-Specific Associations Between Obesity and Nutrition/Health Knowledge, Dietary Diversity, and Physical Activity in Chinese School-Age Students: A Cross-Sectional Study
Gender-, Age-, and Region-Specific Associations Between Obesity and Nutrition/Health Knowledge, Dietary Diversity, and Physical Activity in Chinese School-Age Students: A Cross-Sectional Study Open
Background: Chinese school-age students are at a high risk of developing obesity. However, few studies have reported individualized ways to prevent obesity by age, gender, and living regions. Methods: A total of 11,285 students aged 6–18 y…
View article: Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview
Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview Open
Astragalus polysaccharides (APS), bioactive compounds derived from Astragalus membranaceus, have emerged as promising natural agents in the treatment of hepatocellular carcinoma, a leading cause of cancer-related mortality. Preclinical stu…
View article: Risk factors for developing hypertension in patients with type 2 diabetes: A cross-sectional study
Risk factors for developing hypertension in patients with type 2 diabetes: A cross-sectional study Open
This study explores the prevalence of hypertension in patients with type 2 diabetes mellitus (T2DM) and identifies the potential risk factors associated with the development of hypertension. A cross-sectional study was conducted among 699 …
View article: PTX3 as a diagnostic and prognostic biomarker in lung adenocarcinoma: a comprehensive analysis
PTX3 as a diagnostic and prognostic biomarker in lung adenocarcinoma: a comprehensive analysis Open
PTX3 emerges as a dual biomarker for LUAD diagnosis and prognosis, with mechanistic ties to TME remodeling and therapeutic resistance, highlighting its potential for clinical translation.
View article: Relationship between breastfeeding duration, lifestyle and obesity in children aged 3–16 years: a cross-sectional study
Relationship between breastfeeding duration, lifestyle and obesity in children aged 3–16 years: a cross-sectional study Open
Introduction Childhood obesity is emerging as an increasingly severe public health problem. Effective lifestyle and dietary interventions are urgently needed to prevent childhood obesity. The study explored the association of breastfeeding…
View article: Dietary n-3 polyunsaturated fatty acids intervention ameliorates cognitive dysfunction in db/db mice by mitigating cortical insulin resistance, mitochondrial dysfunction, and energy metabolism impairment
Dietary n-3 polyunsaturated fatty acids intervention ameliorates cognitive dysfunction in db/db mice by mitigating cortical insulin resistance, mitochondrial dysfunction, and energy metabolism impairment Open
n-3 PUFA facilitated the recovery of cognitive function in T2DM mice by regulating cortical mitochondrial energy metabolism and enhancing the glutamate-glutamine cycle.
View article: Impact of vitamin A on aged people’s cognition and Alzheimer’s disease progression in an animal model
Impact of vitamin A on aged people’s cognition and Alzheimer’s disease progression in an animal model Open
The relation between vitamin A (VA) level and cognitive function and the underlying mechanisms have not been thoroughly investigated. Population-based cross-sectional and animal diet intervention studies were conducted to analyze the assoc…
View article: Vitamin D3 Treatment Reduces Epileptic Neuronal Damage by Inhibiting Apoptosis and Increasing Vitamin D Receptor Expression in an In Vivo Epileptic Model
Vitamin D3 Treatment Reduces Epileptic Neuronal Damage by Inhibiting Apoptosis and Increasing Vitamin D Receptor Expression in an In Vivo Epileptic Model Open
Background: Vitamin D (VitD) deficiency is prevalent in more than half of patients treated with antiepileptic drugs. The number of seizures decreases by more than 40% after vitamin D3 supplementation. This study aimed to investigate the an…
View article: Relation between plasma retinol level with different types of dyslipidemia in the middle-aged and the elderly: a cross-sectional study
Relation between plasma retinol level with different types of dyslipidemia in the middle-aged and the elderly: a cross-sectional study Open
View article: Preparations of Mytilus edulis protein hydrolysate-iron complexes and their ameliorative effects on mice with iron deficiency anemia
Preparations of Mytilus edulis protein hydrolysate-iron complexes and their ameliorative effects on mice with iron deficiency anemia Open
View article: Sex-specific association of blood triglyceride and uric acid with body shapes in Chinese adults
Sex-specific association of blood triglyceride and uric acid with body shapes in Chinese adults Open
Background: Abnormal metabolic syndrome, adipose distribution and different body shapes caused by obesity are associated with the levels of blood biochemical indexes. However, the sex-specific relationship between body shapes and blood bio…
View article: Gender, Age and Region-Specific Association between Nutrition and Health Knowledge, Dietary Diversity and Physical Activity with Obesity in Chinese School-Age Students: A Cross-Sectional Study
Gender, Age and Region-Specific Association between Nutrition and Health Knowledge, Dietary Diversity and Physical Activity with Obesity in Chinese School-Age Students: A Cross-Sectional Study Open
View article: Associations of risk factors and the number of risk factors with the classification, GMFCS level and comorbidities with cerebral palsy: a retrospective study
Associations of risk factors and the number of risk factors with the classification, GMFCS level and comorbidities with cerebral palsy: a retrospective study Open
View article: Impact of vitamin A on the risk of mild cognitive impairment and Alzheimer's disease pathology in high‐fat‐diet–treated APP/PS1 mice
Impact of vitamin A on the risk of mild cognitive impairment and Alzheimer's disease pathology in high‐fat‐diet–treated APP/PS1 mice Open
Abnormal glucose metabolism and vitamin A (VA) nutritional status promote the occurrence of cognitive impairment and Alzheimer's disease (AD). However, the effects of low VA intake, insulin resistance, and their interaction on the promotin…
View article: A study of the difference in biochemical metabolism between patients with unilateral and bilateral upper urinary tract stones
A study of the difference in biochemical metabolism between patients with unilateral and bilateral upper urinary tract stones Open
Bilateral upper urinary tract stones are more likely to lead to impairment of renal function, but few biochemical metabolic studies of bilateral upper urinary tract stones have been reported. We collected clinical data from 555 patients wi…
View article: Phenolics‐Rich Extract from Agarwood Leaf‐Tea Alleviate Dextran Sulfate Sodium (DSS)‐Induced Ulcerative Colitis Via Modulating Intestinal Barrier Function, Liver Inflammation, and Gut Microbiota
Phenolics‐Rich Extract from Agarwood Leaf‐Tea Alleviate Dextran Sulfate Sodium (DSS)‐Induced Ulcerative Colitis Via Modulating Intestinal Barrier Function, Liver Inflammation, and Gut Microbiota Open
Scope At present, the incidence rate of ulcerative colitis (UC) continues to increase, causing a global burden. In addition, therapeutic drugs have great side effects. According to modern pharmacology, agarwood leaves have anti‐inflammator…
View article: Physical Activity, Exercise, and Mental Disorders of Older Adults
Physical Activity, Exercise, and Mental Disorders of Older Adults Open
Editorial - No Abstract available.
View article: Developing a risk model for early diagnosis of metabolic syndrome in Chinese adults aged 40 years and above based on BMI/HDL-C: a cross-sectional study
Developing a risk model for early diagnosis of metabolic syndrome in Chinese adults aged 40 years and above based on BMI/HDL-C: a cross-sectional study Open
BMI/HDL-C ratio was an independent risk factor for MS in Chinese adults. BMI/HDL-C was significantly correlated with MS and its components. BMI/HDL-C was the most powerful diagnostic indicator compared to other indicators, including TG/HDL…
View article: Editorial: Food-derived bioactive peptides: preparation, identification, and structure-activity relationship
Editorial: Food-derived bioactive peptides: preparation, identification, and structure-activity relationship Open
Bioactive peptides form a significant group of low molecular weight protein fragments derived from a wide range of foods, including beans, vegetables, meats, dairy, eggs, seafood, and algae. These peptides exist inactive within the structu…
View article: Association of risk factor and the number of risk factors with classification, GMFCS and comorbidity of CP
Association of risk factor and the number of risk factors with classification, GMFCS and comorbidity of CP Open
Objective: To explore the characteristics of risk factors in children with CP, focusing on the effects of single risk factors and the number of risk factors on the classification, GMFCS, and comorbidities of CP. Methods: The medical record…
View article: Prevalence of cerebral palsy comorbidities in China: a systematic review and meta-analysis
Prevalence of cerebral palsy comorbidities in China: a systematic review and meta-analysis Open
Objectives This systematic review aimed to comprehensively understand the comorbidity of cerebral palsy (CP) in China. Methods We searched through databases in both Chinese and English until December 2022 to gather cross-sectional studies …
View article: Association of plasma vitamin A level with type 2 diabetes mellitus: a community aging population-based cross-sectional study
Association of plasma vitamin A level with type 2 diabetes mellitus: a community aging population-based cross-sectional study Open
Recent studies indicated that vitamin A (VA) might be involved in the pathology of type 2 diabetes mellitus (T2DM). This cross-sectional study was conducted to explore the association between circulating VA level and T2DM. A total of 1818 …
View article: Molecular typing and characterization of Staphylococcus aureus isolates from burn wound infections in Fujian, China
Molecular typing and characterization of Staphylococcus aureus isolates from burn wound infections in Fujian, China Open
Background Staphylococcus aureus ( S. aureus ) is the most common causative agent of burn wound infection, that often leads to high morbidity and mortality. However, there is not enough knowledge about the molecular epidemiology and antimi…
View article: Prevalence and related factors of epilepsy in children and adolescents with cerebral palsy: a systematic review and meta-analysis
Prevalence and related factors of epilepsy in children and adolescents with cerebral palsy: a systematic review and meta-analysis Open
Objective To study the worldwide prevalence and associated factors of epilepsy in children and adolescents with Cerebral Palsy (CP) and to analyze the differences between various subgroups. Method We identified all potential studies on the…
View article: Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults
Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults Open
There was association between folate pathway gene polymorphism of Solute Carrier Family 19 Member 1 (SLC19A1) and Methylenetetrahydrofolate Reductase (MTHFR) with erythrocyte SOD and GSH-PX activities, and folate levels in male but not in …
View article: Association of cluster determinant 36, scavenger receptor class B type 1, and major facilitator superfamily domain containing the 2a genetic polymorphism with serum lipid profile in aging population with type 2 diabetes mellitus
Association of cluster determinant 36, scavenger receptor class B type 1, and major facilitator superfamily domain containing the 2a genetic polymorphism with serum lipid profile in aging population with type 2 diabetes mellitus Open
Background Lipid metabolism disorder commonly happens in subjects with Type 2 diabetes mellitus (T2DM) which may be linked to genetic variants of lipid metabolism-related genes. However, few studies have explored the relationship between l…
View article: Preparation, purification, and identification of novel antioxidant peptides derived from Gracilariopsis lemaneiformis protein hydrolysates
Preparation, purification, and identification of novel antioxidant peptides derived from Gracilariopsis lemaneiformis protein hydrolysates Open
Gracilariopsis lemaneiformis ( G. lemaneiformis ) protein was hydrolyzed with alkaline protease to obtain antioxidant peptides. The enzymatic hydrolysis conditions were optimized through single-factor and orthogonal experiments. The result…