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View article: Association between different dimensions of C-reactive protein-triglyceride-glucose index and the incidence of frailty in middle-aged and elderly adults in China: A nationwide prospective cohort study
Association between different dimensions of C-reactive protein-triglyceride-glucose index and the incidence of frailty in middle-aged and elderly adults in China: A nationwide prospective cohort study Open
Background: Inflammation and metabolic disorders significantly contribute to frailty development. The C-reactive protein-triglyceride-glucose index (CTI) indicates both inflammation and insulin resistance (IR). This study delves into the c…
View article: Insights into the synergistic mechanisms of citric acid in detoxifying cadmium in tall fescue
Insights into the synergistic mechanisms of citric acid in detoxifying cadmium in tall fescue Open
Tall fescue (Festuca arundinacea) can potentially be utilized as an accumulator species for cadmium (Cd) phytoremediation, whereas Cd toxicity can be alleviated by citric acid (CA). This study systematically explored the mechanisms of CA i…
View article: MDMX enhances radiosensitivity in lung adenocarcinoma and squamous cell carcinoma by inhibiting P53-mediated autophagy
MDMX enhances radiosensitivity in lung adenocarcinoma and squamous cell carcinoma by inhibiting P53-mediated autophagy Open
View article: Effect of emergency department triage model on door-to-needle time in patients with acute ischemic stroke: a retrospective study
Effect of emergency department triage model on door-to-needle time in patients with acute ischemic stroke: a retrospective study Open
Objective This retrospective study aims to investigate the impact of the emergency department triage model on door-to-needle (DTN) time in patients with acute ischemic stroke (AIS). Methods 641 patients with AIS who used the emergency medi…
View article: Trabeculectomy versus stepwise treatment for breaking the attack of acute primary angle closure in patients with long attack duration: study design and protocol for a multicentre randomised controlled trial (LAAAC)
Trabeculectomy versus stepwise treatment for breaking the attack of acute primary angle closure in patients with long attack duration: study design and protocol for a multicentre randomised controlled trial (LAAAC) Open
Introduction Acute primary angle closure (APAC) is a common ophthalmic emergency for Chinese patients causing potential visual disabilities. According to current guidelines published by developed countries, a stepwise protocol (medication …
View article: Insights into the Synergistic Mechanisms of Citric Acid in Detoxifying Cadmium in Tall Fescue
Insights into the Synergistic Mechanisms of Citric Acid in Detoxifying Cadmium in Tall Fescue Open
View article: Corrigendum to "Single high-frequency repetitive transcranial magnetic stimulation and intermittent theta pulse stimulation promote working memory behavior in participants: An event-related potential study" [Brain Res. Bull. 220 (2025) 111147]
Corrigendum to "Single high-frequency repetitive transcranial magnetic stimulation and intermittent theta pulse stimulation promote working memory behavior in participants: An event-related potential study" [Brain Res. Bull. 220 (2025) 111147] Open
View article: Linking Iris <i>Cis</i>-Regulatory Variants to Primary Angle-Closure Glaucoma Via Clinical Imaging and Multiomics
Linking Iris <i>Cis</i>-Regulatory Variants to Primary Angle-Closure Glaucoma Via Clinical Imaging and Multiomics Open
Our findings underscore the importance of the iris in the pathogenesis of PACG and identified iris-specific, enhancer-modulating variants that may influence disease risk. Our approach also provides a generalizable framework for studying oc…
View article: Loncastuximab in high-risk and heavily pretreated relapsed / refractory diffuse large B-cell lymphoma: a real-world analysis from 21 US centers.
Loncastuximab in high-risk and heavily pretreated relapsed / refractory diffuse large B-cell lymphoma: a real-world analysis from 21 US centers. Open
Outcomes in patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) are poor. Loncastuximab-teserine (Lonca) is an antibody drug conjugate (ADC) which was FDA approved for R/R DLBCL patients who have received at least…
View article: Loncastuximab in high-risk and heavily pretreated relapsed / refractory diffuse large B-cell lymphoma: a real-world analysis from 21 US centers
Loncastuximab in high-risk and heavily pretreated relapsed / refractory diffuse large B-cell lymphoma: a real-world analysis from 21 US centers Open
Outcomes in patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) are poor. Loncastuximab-teserine (Lonca) is an antibody drug conjugate (ADC) which was FDA approved for R/R DLBCL patients who have received at least…
View article: Weekly dynamic tumor regression in a nasopharyngeal carcinoma patient receiving MR-guided radiation therapy
Weekly dynamic tumor regression in a nasopharyngeal carcinoma patient receiving MR-guided radiation therapy Open
Background Although radiation therapy for nasopharyngeal carcinoma is quite effective, the dynamic changes of tumors during radiation therapy have rarely been reported. Initial case studies have shown promising effects of MR-guided radiati…
View article: Comparing 24-hour IOP fluctuation slope curve between newly diagnosed ocular hypertension and primary open-angle glaucoma
Comparing 24-hour IOP fluctuation slope curve between newly diagnosed ocular hypertension and primary open-angle glaucoma Open
Objective To compare the 24-hour intraocular pressure (IOP) fluctuation slope curve between newly diagnosed patients with ocular hypertension (OHT) and primary open-angle glaucoma (POAG). Methods and analysis Newly diagnosed and untreated …
View article: Retinal ganglion cell complex thickness in subjects with diabetes mellitus and uncontrolled hypertension in China
Retinal ganglion cell complex thickness in subjects with diabetes mellitus and uncontrolled hypertension in China Open
View article: Correlation between choroidal parameters and primary angle-closure suspect in different age groups
Correlation between choroidal parameters and primary angle-closure suspect in different age groups Open
Objective To investigate the correlations between choroidal parameters and primary angle-closure suspect (PACS) in different age subgroups. Methods and analysis Participants aged 50 years or older in a rural area of Daxing District, Beijin…
View article: Matching maximum power point of gaas solar cells for a photo-rechargeable system with >26% overall efficiency
Matching maximum power point of gaas solar cells for a photo-rechargeable system with >26% overall efficiency Open
The rapid development of the Internet of Things and portable/wearable electronic devices has posed increasing demands for handy and efficient off-grid powers. Solar self-powered systems are one of the emerging options, yet their performanc…
View article: Characteristics of beta parapapillary atrophy in primary angle-closure suspect
Characteristics of beta parapapillary atrophy in primary angle-closure suspect Open
Objective To investigate the characteristics of beta parapapillary atrophy (β-PPA) in patients with primary angle-closure suspect (PACS). Methods and analysis In total, 215 and 259 eyes with PACS and non-PACS (NPACS), respectively, were en…
View article: Efficacy of Morning Versus Evening Latanoprost/Timolol Fixed Combination for Open-Angle Glaucoma and Ocular Hypertension: A Randomized Clinical Trial
Efficacy of Morning Versus Evening Latanoprost/Timolol Fixed Combination for Open-Angle Glaucoma and Ocular Hypertension: A Randomized Clinical Trial Open
This multicenter, double-blind, randomized clinical trial generates robust evidence on the optimal LTFC dosing regimen to help clinical decision-making in the treatment of raised IOP.
View article: Brentuximab vedotin plus AVD for Hodgkin lymphoma: incidence and management of peripheral neuropathy in a multisite cohort
Brentuximab vedotin plus AVD for Hodgkin lymphoma: incidence and management of peripheral neuropathy in a multisite cohort Open
Brentuximab vedotin (BV) in combination with doxorubicin, vinblastine, and dacarbazine (AVD) is increasingly used for frontline treatment of stage III/IV classical Hodgkin lymphoma (cHL). Peripheral neuropathy (PN) was the most common and …
View article: Parotid tumors and their postoperative complications: A 5-year experience
Parotid tumors and their postoperative complications: A 5-year experience Open
Introduction: Understanding the pathophysiology, clinical characteristics, and postoperative complications of parotid tumors is crucial in light of the growing emphasis on the occurrence and development of parotid tumor disease. Materials …
View article: Factors associated with severe corneal endothelial damage following acute primary angle closure in Chinese subjects
Factors associated with severe corneal endothelial damage following acute primary angle closure in Chinese subjects Open
Purpose To investigate the corneal endothelial damage caused by acute primary angle closure (APAC) and related risk factors for severe corneal endothelial cell damage in Chinese subjects. Methods In this multicentre retrospective study, 16…
View article: Variation in Retinal Nerve Fiber Layer and Ganglion Cell Complex Associated With Optic Nerve Head Size in Healthy Eyes
Variation in Retinal Nerve Fiber Layer and Ganglion Cell Complex Associated With Optic Nerve Head Size in Healthy Eyes Open
GCC may be a better index than RNFL for early glaucoma evaluation in patients with large or small ONH.
View article: Proteomic profiles of the retina in an experimental unilateral optic nerve transection: Roles of Müller cell activation
Proteomic profiles of the retina in an experimental unilateral optic nerve transection: Roles of Müller cell activation Open
Retinal ganglion cell (RGC) degeneration is a common pathogenesis in multiple ocular disorders and was studied in animal reproducible models of optic nerve transection (ONT) for the neuronal apoptosis in the adult central nervous system.1-…
View article: Predictors of angle widening after laser iridotomy in Chinese patients with primary angle-closure suspect using ultrasound biomicroscopy
Predictors of angle widening after laser iridotomy in Chinese patients with primary angle-closure suspect using ultrasound biomicroscopy Open
AIM: To assess the predictive value of baseline parameters of ultrasound biomicroscopy (UBM) for angle widening after prophylactic laser peripheral iridotomy (LPI) in patients with primary angle-closure suspect (PACS). METHODS: Angle-openi…
View article: Retina Vascular Structures near the Optic Disc and in the Macula in Primary Angle-Closure Suspects
Retina Vascular Structures near the Optic Disc and in the Macula in Primary Angle-Closure Suspects Open
Introduction: The main aim of this article was to study the retinal peripapillary and macular vascular structures in eyes with primary angle-closure suspects (PACS) using optical coherence tomography angiography (OCTA).
View article: Repeatability and Reproducibility of Anterior Chamber Angle Measurement with Swept-Source Optical Coherence Tomography in Patients with Primary Angle Closure Suspect
Repeatability and Reproducibility of Anterior Chamber Angle Measurement with Swept-Source Optical Coherence Tomography in Patients with Primary Angle Closure Suspect Open
Purpose: To evaluate the inter- and intra-observer reliability of anterior chamber (AC) angle measurements obtained by swept-source optical coherence tomography (SS-OCT). Methods: Forty-eight consecutive patients diagnosed wi…
View article: Summary of Target Detection Algorithms
Summary of Target Detection Algorithms Open
In recent years, the soaring development of CNN has facilitated the maturity of the Computer Vision Algorithm. This paper will briefly introduce some representative Target Detection Algorithm, and systematically analyze the underlying prob…
View article: Effect of Segmented Thermal Aging on Defect Location Accuracy in XLPE Distribution Cables
Effect of Segmented Thermal Aging on Defect Location Accuracy in XLPE Distribution Cables Open
Frequency domain reflectometry (FDR) technologies could be applied to locate defects in cables effectively. Owing to the large space span and complex operating environment of the actual XLPE distribution cables, segmented thermal aging phe…
View article: Repeatability and Reproducibility of Anterior Chamber Angle Measurement with Swept-Source Optical Coherence Tomography in Patients with Primary Angle Closure Suspect
Repeatability and Reproducibility of Anterior Chamber Angle Measurement with Swept-Source Optical Coherence Tomography in Patients with Primary Angle Closure Suspect Open
Purpose: To evaluate the inter- and intra-observer reliability of anterior chamber (AC) angle measurements obtained by swept-source optical coherence tomography (SS-OCT). Methods: Forty-eight consecutive patients diagnosed wi…
View article: Ganglion Cell Complex Parameters in Primary Angle Closure Suspects
Ganglion Cell Complex Parameters in Primary Angle Closure Suspects Open
Introduction: This study aimed to investigate the ganglion cell complex (GCC) parameters in primary angle closure suspects (PACS) and identify the related factors. Methods: A total of 731 subjects, including 289…
View article: Quantitative determination of D4-cystine in mice using LC-MS/MS and its application to the assessment of pharmacokinetics and bioavailability
Quantitative determination of D4-cystine in mice using LC-MS/MS and its application to the assessment of pharmacokinetics and bioavailability Open