Shunta Hashiguchi
YOU?
Author Swipe
View article: Photocrosslinked films composed of polydimethylsiloxane bearing alicyclic epoxy units and their CO₂-selective permeation properties
Photocrosslinked films composed of polydimethylsiloxane bearing alicyclic epoxy units and their CO₂-selective permeation properties Open
Various crosslinked PDMS films incorporating cyclic epoxy groups were prepared by UV-induced acid generation and thermal curation and evaluated as CO₂-selective permeable membranes. These free-standing, ultrathin PDMS films (~100 nm thick)…
View article: Siponimod inhibits microglial inflammasome activation
Siponimod inhibits microglial inflammasome activation Open
Siponimod is the first oral drug approved for active secondary progressive multiple sclerosis. It acts as a functional antagonist of sphingosine-1-phosphate (S1P) receptor 1 (S1P1) through S1P1 internalization, and al…
View article: Brain biopsy and metagenomic sequencing enhance aetiological diagnosis of encephalitis
Brain biopsy and metagenomic sequencing enhance aetiological diagnosis of encephalitis Open
Identifying the aetiology of CNS diseases, regardless of their infectious or non-infectious nature, is often intricate. Next-generation sequencing (NGS) has emerged as a powerful tool for sensitive and unbiased screening of tissue or body …
View article: A case report of an individual with Creutzfeldt–Jakob disease characterized by prolonged isolated thalamic lesions and rare MM2-cortical-type pathology
A case report of an individual with Creutzfeldt–Jakob disease characterized by prolonged isolated thalamic lesions and rare MM2-cortical-type pathology Open
View article: Totally Implantable Central Venous Access Port-Associated Bloodstream Infection Caused by Corynebacterium provencense: The First Case Report
Totally Implantable Central Venous Access Port-Associated Bloodstream Infection Caused by Corynebacterium provencense: The First Case Report Open
View article: Lateral olfactory tract usher substance (LOTUS), an endogenous Nogo receptor antagonist, ameliorates disease progression in amyotrophic lateral sclerosis model mice
Lateral olfactory tract usher substance (LOTUS), an endogenous Nogo receptor antagonist, ameliorates disease progression in amyotrophic lateral sclerosis model mice Open
View article: Phosphorylated CRMP1, axon guidance protein, is a component of spheroids and is involved in axonal pathology in amyotrophic lateral sclerosis
Phosphorylated CRMP1, axon guidance protein, is a component of spheroids and is involved in axonal pathology in amyotrophic lateral sclerosis Open
In amyotrophic lateral sclerosis (ALS), neurodegeneration is characterized by distal axonopathy that begins at the distal axons, including the neuromuscular junctions, and progresses proximally in a “dying back” manner prior to the degener…
View article: Inhibition of Crmp1 Phosphorylation at Ser522 Ameliorates Motor Function and Neuronal Pathology in Amyotrophic Lateral Sclerosis Model Mice
Inhibition of Crmp1 Phosphorylation at Ser522 Ameliorates Motor Function and Neuronal Pathology in Amyotrophic Lateral Sclerosis Model Mice Open
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal neurodegenerative disorder that affects upper and lower motor neurons; however, its pathomechanism has not been fully elucidated. Using a comprehensive phosphoproteomic…
View article: Porous Gold Nanomesh Films Electrodeposited in Toluene-Based Dynamic Soft Template
Porous Gold Nanomesh Films Electrodeposited in Toluene-Based Dynamic Soft Template Open
View article: Case Report: Takotsubo Cardiomyopathy in Bickerstaff Brainstem Encephalitis Triggered by COVID-19
Case Report: Takotsubo Cardiomyopathy in Bickerstaff Brainstem Encephalitis Triggered by COVID-19 Open
Takotsubo cardiomyopathy (TCM) is a stress-induced cardiomyopathy triggered by critical illness including severe neurological disorders. However, an association between TCM and Bickerstaff brainstem encephalitis (BBE) has rarely been descr…
View article: “COVID arm” detected by MR neurography
“COVID arm” detected by MR neurography Open
View article: SGTA associates with intracellular aggregates in neurodegenerative diseases
SGTA associates with intracellular aggregates in neurodegenerative diseases Open
View article: SGTA associates with intracellular aggregates in neurodegenerative diseases.
SGTA associates with intracellular aggregates in neurodegenerative diseases. Open
Intracellular aggregates are a common pathological hallmark of neurodegenerative diseases such as polyglutamine (polyQ) diseases, amyotrophic lateral sclerosis (ALS), Parkinson’s disease (PD), and multiple system atrophy (MSA). Aggregates …
View article: Ataxic phenotype with altered CaV3.1 channel property in a mouse model for spinocerebellar ataxia 42
Ataxic phenotype with altered CaV3.1 channel property in a mouse model for spinocerebellar ataxia 42 Open
View article: Matrin 3 Is a Component of Neuronal Cytoplasmic Inclusions of Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis
Matrin 3 Is a Component of Neuronal Cytoplasmic Inclusions of Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis Open
View article: A case of cerebral venous thrombosis caused by idiopathic hypertrophic pachymeningitis
A case of cerebral venous thrombosis caused by idiopathic hypertrophic pachymeningitis Open
症例は41 歳男性．亜急性に進行した頭痛と行動異常が認められ緊急入院となった．入院時は，意識清明だが高揚感があり，軽度認知機能障害と項部硬直を認めた．脳MRI で硬膜が肥厚しており，上矢状静脈洞にdelta sign も認めていたため，MRV を追加したところ上矢状静脈洞と右横静脈洞が描出不良であった．肥厚性硬膜炎に脳静脈洞血栓症を合併した病態と考え，ヘパリンを併用しながら大量ステロイド療法を施行した．臨床症状が改善したため，ステロイド剤と抗凝固薬の内服に切り替え，自宅退院…
View article: Interleukin 10 Level in the Cerebrospinal Fluid as a Possible Biomarker for Lymphomatosis Cerebri
Interleukin 10 Level in the Cerebrospinal Fluid as a Possible Biomarker for Lymphomatosis Cerebri Open
A 71-year-old immunocompetent man developed cognitive decline and gait disturbance. Brain magnetic resonance imaging (MRI) revealed bilateral diffuse leukoencephalopathy without a mass lesion. An analysis of the cerebrospinal fluid (CSF) s…